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  • Eye disorders in golden retrievers linked to novel mutation in TTC8

    The authors use whole genome scanning to identify an association between the gene TTC8 and inherited eye disorders in golden retrievers. A single mutation in TTC8 was found by DNA sequencing, and then confirmed by screening a larger number of dogs.

    Canine Genetics and Epidemiology 2014, 1:4
  • Genetics of eye disorders in the dog

    Cathryn Mellersh looks at the mutations that have been associated with inherited eye disorders in the dog. Similarities between eye structure and disease in humans and dogs point to an increased role for dogs in helping us to understand and treat eye disorders in both species.

    Canine Genetics and Epidemiology 2014, 1:3
  • Approaches to canine health surveillance

    Authors at the Royal Veterinary College and the University of Sydney review the history and development of health surveillance systems in canine medicine. These systems each have their own strengths and weaknesses when it comes to monitoring dog health.

    Canine Genetics and Epidemiology 2014, 1:2
  • Every dog has its day: a new journal for canine genetics and epidemiology

    We are delighted to announce the launch of Canine Genetics and Epidemiology, an open access journal published by BioMed Central with the support and backing of the UK Kennel Club.

    Canine Genetics and Epidemiology 2014, 1:1
  • Image attributed to: From Rico et al.

    Gene expression in patient-derived xenografts

    Transcriptomic analysis shows for the first time that patient-derived xenografts in mice are more closely related to primary tumors than cell lines are for pancreatic tumors.

    Genome Medicine 2014, 6:27
  • Image attributed to: NASA, Wikimedia Commons

    African microbiome research

    Leading researchers present their recommendations for harnessing microbiome and probiotic research in Sub-Saharan Africa.

    Microbiome 2014, 2:12
  • VMCL vaccination for metastatic melanoma

    Prolonged, repeated Vaccinia Melanoma Cell Lysate vaccination immunotherapy appears to be a clinically effective means of generating high Complete Response rates and long-term survivals, which could be explained by successive immunomodulation

    Journal for ImmunoTherapy of Cancer 2014, 2:9
  • Performance on a pattern separation task

    A pattern separation test in mild to moderate Alzheimer’s disease patients suggests a possible genetic link to poor hippocampal neurogenesis, with performance related to apolipoprotein ϵ4 status and cerebrospinal fluid amyloid-β42 levels.

    Alzheimer's Research & Therapy 2014, 6:20
  • Image attributed to: istock

    Orthogeriatric care improves mobility

    In a randomized trial, perioperative orthogeriatric care does not reduce delirium and cognitive decline in hip fracture patients, but has a positive effect on mobility, highlighting a need for integration of orthopedic and geriatric services.

    BMC Medicine 2014, 12:63
  • HDAC inhibitors in tumor control

    The histone deacetylase inhibitor,  LBH589 increases the in vivo antitumor response of adoptive T cell therapy by creating a favourable cytokine response and increased expansion of polyfunctional T cells

    Journal for ImmunoTherapy of Cancer 2014, 2:8
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    BioMed Central is pleased to announce that Nuclear Receptor Signaling is now open for submissions. The journal has published reviews and commentaries with the Nuclear Receptor Signaling Atlas (NURSA) since 2004, but will now also consider primary research articles following its transfer.  The goal of NURSA is to accrue, develop, and communicate information that advances our understanding of the roles of nuclear receptors in human diseases and conditions in which they play an integral role. for further information please visit the journal.

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    Canadian Journal of Kidney Health and Disease

    BioMed Central is proud to announce that Canadian Journal of Kidney Health and Disease is now accepting submissions. This new title is the official journal of the Canadian Society of Nephrology, and aims to publish the highest quality publications focused on clinical, translational and health services delivery research in the field of chronic kidney disease, dialysis, and kidney transplantation. For further information please visit the journal.

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    BPDED affiliates with NEA.BPD

    We are pleased to announce that Borderline Personality Disorder and Emotion Dysregulation is now the official journal of NEA.BPD; an organisation dedicated to raising public awareness, providing education and promoting research on borderline personality disorder.

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    Celebrating one year of success for Infectious Diseases of Poverty journal

    One year on and BioMed Central’s journal Infectious Diseases of Poverty, launched at the 2nd Symposium on Health Systems Research, has successfully published four thematic series and 41 articles with submissions ranging across 39 countries.  These submissions include papers from countries with low and middle income economic  status. For further information please visit the blog.

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