Novel regulatory mechanisms of translational response to oxygen and glucose deprivation in mammalian cells
Carol Fabian et al. review early investigations into the use of omega-3 supplementation to prevent breast cancer and to improve outcomes following breast cancer diagnosis.
In a randomized trial, an equation based on procalcitonin and pyuria reduces prescription of antibiotics for urinary tract infections (UTIs) without affecting clinical outcome, suggesting that algorithms could reduce inappropriate antibiotic use.
As part of the "Human Evolutionary Genomics" thematic series, Michael Hofreiter and colleagues review how recent technological improvements have rapidly transformed ancient human DNA research to become a central component of modern anthropological research.
Wollstein and Lao discuss the most widely used methods in population genetics for evaluating individual genetic ancestry.
A multiplex assay for simultaneous detection of H7N9 and influenza A viruses was developed, enabling the laboratory surveillance and rapid diagnosis of these viruses in the future.
In an analysis of epidemiological and clinical data, recent outbreaks of Chikungunya virus in Brazil are caused by imported strains, suggesting surveillance and vector mitigation measures are required to avoid uncontrolled transmission in America.
Alfgeir Kristjansson and Inga Dora Sigfusdottir discuss the use of electronic cigarettes (ECs) in adolescents, concluding that ECs are likely to increase the risk of other harmful behaviours such as alcohol use, so their use should be restricted in minors.
Wei-Qi Wei and Joshua Denny review how the combination of data extracted from EHRs with high-throughput genotyping information can accelerate genomic discovery.
Treatment of NV-01, a monoclonal canine-specific antibody against nerve growth factor, decreased pain and improved mobility in dogs with degenerative joint disease-associated pain, with the magnitude of the effect appearing identical to that expected with an NSAID.
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