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  • Image attributed to: Santosa et al.

    Reduced burden of NCDs met by Sweden

    Sweden, a country at a late stage of epidemiological transition, has exceeded the  target of 25% reduction in premature mortality due to non-communicable diseases (NCDs), suggesting other countries at earlier stages of development may achieve this goal.

    BMC Medicine 2015, 13:65
  • Effects of study design and allocation on self-reported alcohol consumption: randomized trial

    The design and allocation of participants in a study could affect behavior and bias findings. However, the study design and allocation of participants in a self-reported alcohol consumption study did not affect drinking behavior.

    Trials 2015, 16:127
  • Time to rethink the systematic review catechism? Moving from ‘what works’ to ‘what happens’

    As the methodological aspects to a systematic review develop, the key principles behind them may need to be reevaluated to address more complex questions and interventions; for example, future research should focus on publication bias in qualitative research and the incorporation of a systems perspective.

    Systematic Reviews 2015, 4:36
  • Germline epigenome reprogramming

    Epigenetic effects of endocrine disrupting chemicals in germ cells are corrected by germline reprogramming events in the next generation

    Genome Biology 2015, 16:59
  • Diagnosing and managing PCOS

    In this podcast, Richard Legro, an obstetrician and gynecologist, answers our questions on the diagnosis and treatment of polycystic ovary syndrome (PCOS) and highlights the controversies associated with therapies for infertility in PCOS.

    BMC Medicine 2015, 13:64
  • Image attributed to: wikimedia commons-Jeff Weiss

    Host immunity determines influenza virus infection

    Diverse clinical response to two strains of influenza virus in ferrets demonstrated that host immunity, not the virus strain, was the determinant in the outcome of influenza virus infection. 

    Virology Journal 2015, 12:48
  • Image attributed to: istock photo

    Breast cancer chemoprevention

    Evidence from randomized trials suggests that taking selective estrogen receptor modulators could reduce breast cancer risk; Victor Vogel comments on the latest results, recommending that the risks and benefits should be considered for each individual.

    BMC Medicine 2015, 13:63
  • Making rare diseases visible

    Following revision of the International Classification of Diseases, the European Commission Expert Group on Rare Diseases recommends health care coding systems to use ORPHA codes in addition to ICD10 codes for rare diseases.

    Orphanet Journal of Rare Diseases 2015, 10:35
  • Image attributed to: Harten, BMC Biology 2015

    Genome-wide activity of an epigenetic modifier

    Emma Whitelaw and colleagues explore the genome-wide consequences of the absence of a recently-identified epigenetic modifier, reporting effects on methylation at thousands of loci in embryonic mice, with a bias towards activity at CpG island shores and enhancers.

    BMC Biology 2015, 13:21
  • Genome-to-phenome with FAANG

    The FAANG Consortium introduces a new project to produce comprehensive maps of functional elements in the genomes of domesticated animal species.

    Genome Biology 2015, 16:57
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