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  • Image attributed to: TheeErin on Flickr

    Support needed during HCV therapy

    Hepatitis C virus (HCV) patients undergoing outpatient protease-inhibitor-based triple therapy can find the treatment physically, emotionally and socially draining, and need systematic support from specially trained professionals in symptom management.

    BMC Infectious Diseases 2014, 14:507
  • Image attributed to: Detail from Figure 1

    Cancer therapy leads from yeast conservation

    Screens in yeast can be used to identify conserved interactions with the mismatch repair pathway to provide new avenues for cancer therapy based on synthetic lethality.

    Genome Medicine 2014, 6:68
  • Image attributed to: Authors' figure of a pie chart

    Informed consent in childhood cancer sequencing

    Consent for clinical tumor sequencing in children is more dependent on emotional aspects than race or ethnicity, while genomic privacy concerns are low.

    Genome Medicine 2014, 6:69
  • Inter-hospital transfer and mortality in AKI patients

    Inter-hospital transfer of critically ill patients with acute kidney injury (AKI) does not increase risk of death or dialysis dependence 30 days after the initiation of acute renal replacement therapy.

    Critical Care 2014, 18:513
  • Image attributed to: Flickr: Caro Wallis

    Goals for sugar intake should be revised

    There is a log-linear relationship of caries to sugar intake from 0% of energy intake (E) to 10%E sugar at where a costly burden of caries is induced, suggesting public health goals should set sugar intakes ideally less than 3%.

    BMC Public Health 2014, 14:863
  • Image attributed to: MDougM, Wikimedia Commons

    Metabolism and angiogenesis

    Peter Carmeliet reviews how metabolic pathways in endothelial cells regulate angiogenesis during cancer development, providing a hugely useful resource for the cancer metabolism field

    Cancer & Metabolism 2014, 2:19
  • Bronchial epithelial cells in Z-AATD COPD

    Bronchial epithelial cells (BECs) from patients with Z variant alpha-1 antitrypsin (Z-AAT) deficiency, express and secrete Z-AAT and its polymers, suggesting that these cells are involved in the pathogenesis of emphysema and BEC dysfunction.

    Respiratory Research 2014, 15:112
  • Evaluating the Y chromosomal timescale

    The Y-chromosome can be used for paternal demographic and lineage dating, however owing to naturally occuring mutations, results can be incaccurate. Looking into a solution for one of the biggest problems in Y-chromosome phylogenetic studies.

    Investigative Genetics 2014, 5:12
  • Image attributed to: Mitou et al. International Journal of Plant Genomics (CC-BY)

    Targeting autophagy in cancer

    Eileen White discusses how cancer cells use autophagy to survive in low nutrient conditions and how new drugs targeting this process can be used to treat cancer.

    Cancer & Metabolism 2014, 2:14
  • Histone marks: an alternative form of protection for sperm

    Repression of mobile genetic elements is essential for the survival of germ cells. A new pathway for silencing LINE-1 elements is described by Donal O'Carroll and colleagues.

    Epigenetics & Chromatin 2014, 7:24
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BioMed Central news

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    Cerebellum & Ataxias has now fully launched

    We are delighted to announce that Cerebellum & Ataxias has now fully launched with BioMed Central and published its first articles. It is the sister journal to The Cerebellum (published by Springer), and is devoted to cerebellar research and cerebellar disorders, including scientific reports and clinical cases of the numerous forms of ataxias.

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    Neurovascular Imaging is now accepting submissions

    Neurovascular Imaging will provide a venue for researchers and clinicians interested in neurovascular imaging techniques in health and disease, allowing for the comparison and juxtaposition of different imaging modalities, and research into the use of imaging techniques in the study, diagnosis and long-term clinical assessment of neurovascular disorders and their pathological mechanisms.

    Led by Editor-in-Chief Dr Luca Saba (University of Cagliari), Neurovascular Imaging is supported by an expert Editorial Board, and is the latest addition to our portfolio of neurology journals.

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    Porcine Health Management (PHM) is now accepting submissions.

    BioMed is pleased to announce that this new society journal is accepting submissions. It is the official publication of the European Association for Porcine Health Management (EAPHM) and European College for Porcine Health Management (ECPHM). Both societies have institutional memberships with BioMed Central and will cover all article processing charges for their members.

    PHM aims to cover all aspects of swine health medicine and production. This will include research on swine health and production, including infectious and non-infectious diseases, reproduction, epidemiology, management, economics, genetics, housing, nutrition, animal welfare and ethics, legislation, food safety, drugs and surgery.

    The Editors-in-Chief of PHM are Stanley Done (just retired after a long career at the Animal Health and Veterinary Laboratories Agency UK) and Guy-Pierre Martineau, an experienced veterinarian at the French National Veterinary School in Toulouse, and the journal is supported by an international editorial board of swine experts.

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    Zoological Letters is now open for submissions.

    Zoological Letters will publish important and valuable discoveries in various fields of zoology. The journal welcomes submissions of both basic and comparative zoology of broad interest to zoologists worldwide. As a sister journal to Zoological Science, Zoological Letters covers a wide range of basic fields of zoology, from taxonomy to bioinformatics.

    Led by Editor-in-Chief Shigeru Kuratani, Center for Developmental Biology, RIKEN, the journal hopes to mirror and even surpass the success of its sister journal Zoological Science

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