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  • Image attributed to: flickr, cc EtanSivad

    Finding the needle in the haystack?

    Bruce Budowle discusses a new approach to differentiate identical twins in paternity testing and forensics.

    Investigative Genetics 2014, 5:11
  • Image attributed to: From de Bekker et al 2014

    Mind control in zombie ants

    Parasitic Ophiocordyceps fungi, who turn their ant hosts into ‘zombies’, can infect and kill multiple ant species but only manipulate behaviour in their specific host species; this could be related to the metabolites they secrete.

    BMC Evolutionary Biology 2014, 14:166
  • Colorectal cancer mutations

    An analysis of the deep targeted sequencing and WGS of matched primary and metastatic colorectal cancer shows high mutations concordance

    Genome Biology 2014, 15:454
  • Metformin as a cancer therapeutic

    Metformin, a diabetes drug, altered mitochondrial activity by acting on Complex I, with a particularly strong effect on cancer cells, supporting its use as a cancer therapeutic.

    Cancer & Metabolism 2014, 2:12
  • Breast cancer classification

    IntClust is a genome-driven breast cancer classifier which subtypes these cancers based on gene expression alone

    Genome Biology 2014, 15:431
  • Image attributed to: Polymeros et al., BMC Medicine

    No molecular link between measles and IBD

    Homology exists between measles antigens and intestinal proteins, but antibody reactivity is not significantly greater in inflammatory bowel disease (IBD) patients than healthy controls, providing further evidence against a link between measles and IBD.

    BMC Medicine 2014, 12:139
  • Tumor heterogeneity

    Charles Swanton and colleagues review the ins and outs of intratumor heterogeneity and how does it affect personalized medicine

    Genome Biology 2014, 15:453
  • N-of-1 studies

    Obi Griffith, Andrew Su and colleagues discuss the challenges of combining the genomic knowledge and N-of-1 studies to improve personalized medicine

    Genome Biology 2014, 15:438
  • Gastric cancer N-of-1

    David Adams and colleagues discuss the elegant approach for the cancer evolution studies, combining sequencing with the clever choice of cancer models

    Genome Biology 2014, 15:444
  • Gastric cancer evolution

    Tumor evolution in a diffuse gastric cancer patient and cancer modeling reveals the metastatic contribution of Tgfbr2 loss-of-function

    Genome Biology 2014, 15:428
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