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  • Intra-tumor heterogeneity evaluation

    A new method for the estimation of intra-tumor heterogeneity from single sample SNP array and sequencing data

    Genome Biology 2014, 15:470
  • Image attributed to: Abramsky et al. (2014)

    Preventing violence against women

    Angela Taft and Rhonda Small comment on the recently published SASA! trial, which successfully reduced acceptance and incidence of partner violence in Uganda, and discuss the importance of community based interventions to address this problem.

    BMC Medicine 2014, 12:155
  • Rat Genome Database Pathway Portal

    A new resource offering a range of pathway data and visualization, including disease pathways and related pathway suites.

    Human Genomics 2014, 8:17
  • Image attributed to:

    Dasatinib drug combination in uterine LMS

    Dasatinib inhibits the SRC pathway in uterine leiomyosarcoma (uLMS) cell lines and yields a synergistic effect with the two-drug combination of either gemcitabine or docetaxel.

    Gynecologic Oncology Research and Practice 2014, 1:2
  • Influenza susceptibility increased in the lung epithelium of elderly

    The mechanisms of aging increase susceptibility of the distal lung epithelium to influenza infection and delay the lung repair process contributing to the severity of the infection in the elderly.

    Respiratory Research 2014, 15:116
  • Image attributed to: http://commons.wikimedia.org/wiki/File:Simvastatin_3D.png

    Predicting statin response

    Using transcriptomic and other genomic data it is possible to predict a subject’s reduction in cholesterol levels in response to statins

    Genome Biology 2014, 15:460
  • Image attributed to: istock

    Delirium diagnosis varies with criteria

    Strict adherence to the DSM-5 criteria results in fewer delirium diagnoses than when DSM-IV are used, whereas applying ‘relaxed’ DSM-5 criteria identifies a comparable number of cases, supporting a more relaxed approach for delirium diagnosis.

    BMC Medicine 2014, 12:164
  • Image attributed to: iStock

    Apps to detect atrial fibrillation

    Hans-Christoph Diener and colleagues discuss screening methods for atrial fibrillation (AF) and call for immediate research into self-administered AF screening techniques using mobile technology which may aid the detection of pulse irregularities.

    BMC Medicine 2014, 12:180
  • Image attributed to: iStock

    Abortion refusal linked to IPV

    Women who have an abortion experience less intimate partner violence (IPV) than women who are denied abortions, indicating that policies to restrict abortion provision may put both women and children at increased risk of violence.

    BMC Medicine 2014, 12:144
  • Methclone

    A new method for studying cancer heterogeneity and subclonality through identification of epigenetic loci affected by the clonal evolution

    Genome Biology 2014, 15:472
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