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  • miRNAs in DLBCL

    miRNA sequencing in diffuse large B-cell lymphoma reveals many novel miRNAs, as well as some that are associated with survival

    Genome Biology 2015, 16:18
  • Image attributed to: Flickr; suparna sinha

    Fetal liver affected by exposure to cigarettes

    Exposure to cigarette smoke leads to sex-specific epigenetic changes and disruption to key metabolic pathways in human fetal liver tissue (from 11-21 weeks of gestation), highlighting the impact of maternal smoking in early pregnancy.

    BMC Medicine 2015, 13:18
  • Image attributed to: From Fig 2 Valencia and colleagues

    CLL and gene expression variability

    A relationship between disease subtype in chronic lymphocytic leukemia and variation in gene expression suggests that variability has an effect on tumor adaptability and aggressiveness.

    Genome Medicine 2015, 7:8
  • Image attributed to: Flickr CC European Commission DG ECHO

    Nutrition supplement improves CD4 count

    A lipid-based nutritional supplement (LNS) with added micronutrients does not decrease mortality in malnourished HIV-infected adults compared with LNS alone, but improves the CD4 count, suggesting this intervention may provide clinical benefits.

    BMC Medicine 2015, 13:17
  • Image attributed to: From Fig 1 Ruklisa et al.

    APPRAISE variant pathogenicity

    Disease-specific Bayesian models provide a robust, accurate and transparent framework to integrate multiple sources of evidence for the interpretation of novel variants from gene sequencing.

    Genome Medicine 2015, 7:5
  • Image attributed to: istock photo

    Low Hb linked to mortality in preterm infants

    Low levels of haemoglobin (Hb) at birth are associated with greater risk of mortality and requirement for blood transfusion in preterm infants, providing support for delayed cord clamping to improve Hb levels and reduce the complications of prematurity.

    BMC Medicine 2015, 13:16
  • DMRcate

    A new method for de novo identification of differentially methylated regions in the human genome.

    Epigenetics & Chromatin 2015, 8:6
  • Image attributed to: Flickr CC (DFID)

    Surveys can estimate NCD prevalence

    Diagnosis of non-communicable diseases (NCDs) using household surveys is accurate in estimating NCD prevalence, which could provide higher resolution estimates and more flexible data collection in areas of low health information infrastructure.

    BMC Medicine 2015, 13:15
  • Image attributed to: Image in public domain

    Certain dog breeds may be predisposed to mast cell tumours

    Data from the VetCompass animal surveillance project suggests that the Boxer, Golden Retriever, and Weimeraner breeds are predisposed to mast cell tumours, relative to other breeds.

    Canine Genetics and Epidemiology 2015, 2:1
  • Adipose tissue methylation

    A global DNA methylation analysis of obesity genes in adipose tissue before and after gastric bypass and weight loss

    Genome Biology 2015, 16:8
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