In resource-limited settings, having multiple conditions is associated with limitations in daily living, depression and poor health, especially among those with lower socioeconomic status, highlighting the need for interventions to reduce multimorbidity.
HiCap is a high resolution method, combining sequence capture and Hi-C, for identifying enhancer-promoter interactions
Estrogen receptor is linked to long-range changes in higher-order chromatin organisation and epigenetic dysregulation in breast cancer
Expression of a phosphorylated STAT3 (pSTAT3)-associated gene signature is linked to trastuzumab resistance in HER2-positive breast cancer, suggesting that agents targeting the STAT3 pathway could help overcome resistance in the clinical setting.
hiBA-FISH is a high-throughput method for automatically detecting DNA breaks and translocations in FISH images
English Cocker spaniels in Denmark risk inheriting distichiasis, an uncomfortable additional row of cilia on the eyelid margin. Could selective breeding benefit the breed?
The involvement of BRCA1 and BRCA2 in breast and ovarian cancers is widely recognised; Helen Cavanagh and Katherine Rogers review the evidence for the role of BRCA1/2 in other cancer types.
A score derived from the Fluid As Expansive Supportive Therapy (FEAST) trial can be used for emergency triage in a low-income pediatric setting, which could increase the number of hospitals in such settings that successfully implement the triage process.
A combination of low birth weight and unhealthy lifestyle is more strongly associated with hypertension risk than either variable alone, indicating that prenatal and postnatal factors could influence hypertension risk.
Regional citrate anticoagulation is being increasingly used during CRRT as an alternative to systemic heparin anticoagulation. Our results suggest that the implementation of regional citrate anticoagulation was safe and effective on a surgical and trauma ICU.
- Editor's picks in my subject areas
- Information for authors
- OA and developing world
- Information for librarians
- BioMed Central Members
- Information for advertisers
- Open Repository
- Publishing services
- Additional services
- Reasons to publish
- Press centre
- Social networks
- BioMed Central events
- Reprints and permissions
- Biome magazine