Evidence from a systematic review and meta-analysis of over 30 million births indicates that the risk of stillbirth in males is around 10% higher than in females, suggesting further research is required to understand the cause of excess male risk.
Oral testosterone replacement therapy (TRT) leads to significant cardiovascular (CV) risk, whereas injected or transdermal TRT do not, which could be due to the different routes of administration, which might affect serum dihydrotestosterone.
Zinc protoporphyrin (ZPP) measured in blood has limited ability to identify iron deficiency in Kenyan pregnant women, and cannot reliably rule out the condition, suggesting that guidelines on the use of ZPP to assess iron status require revision.
Blood transcriptional profiling of patients with sepsis, including survivors and non-survivors, reveals survival is associated with a strong immune response and with missense variants in VPS9D1.
Survival analysis methodologies have been adapted to genomic analysis to link molecular information with clinical outcomes. Chen et al. provide an overview of currently available software, web applications and databases specifically developed for survival analysis in genomics research.
Estimating growth rates from fossil bones is difficult, depending on counting lines of arrested growth or measuring density; a comparison of dinosaur bones suggests that, due to variation between bones and individuals, both methods can be unreliable.
The wings of Kallima butterflies mimic the patterns of leaves to a remarkable degree; this adaptation seems to have evolved not through large evolutionary leaps, as some suspected, but gradually over millions of years.
A new database, the most comprehensive and thorough analysis of mitochondrial gene content to date, has implications for the deep phylogeny of eukaryotes and provides an important resource for researchers in genome evolution.
Job Dekker proposes two ways the mammalian genome folds during the cell cycle, through insights obtained with chromosome conformation capture technology.
In a study of three large cohorts and a meta-analysis, total dairy intake is not associated with type 2 diabetes (T2D) incidence, but increased yogurt consumption is linked to reduced risk of T2D, suggesting that yogurt could have a protective effect.
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