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    Verbal autopsy can quantify SCD burden

    Verbal autopsy tools have strong agreement with hospital diagnoses in identifying sickle cell disease (SCD) as a cause of death in children, suggesting they will be useful to quantify the contribution of SCD to childhood mortality in Africa.

    BMC Medicine 2014, 12:65
  • TNF alpha inhibitor therapy can decrease erosion

    Axial spondyloarthritis patients receiving tumor necrosis factor (TNF) alpha inhibitor therapy experience greater fat metaplasia and less erosion in the sacroiliac joints in comparison to standard therapy.

    Arthritis Research & Therapy 2014, 16:R100
  • Surveillance leads to rabies reduction

    Introduction of a national surveillance programme for rabies has led to a reduction in incidence of the disease with regulation of post-exposure prophylaxis quality together with improved management and vaccination of domesticated animals key for its success.

    BMC Infectious Diseases 2014, 14:212
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    Impact of obesity on healthcare

    Andrew Renehan and Iain Buchan comment on a recent large scale study showing that elevated body mass index is linked to increased hospital admission rates in England, and discuss the direct impact of obesity on the healthcare system.

    BMC Medicine 2014, 12:64
  • Regulators of TRAIL in breast cancer

    Novel molecular regulators of the tumor necrosis factor-related apoptosis inducing ligand (TRAIL) pathway in breast cancer cells were identified, suggesting their role in combination with TRAIL as potential therapeutic targets for breast cancer.

    Breast Cancer Research 2014, 16:R41
  • Image attributed to: Katia Del Rio-Tsonis - a chick eye at E4 (BrdU staining)

    Understanding retinal regeneration

    Following injury of the retinal pigmented epithelium (RPE), dedifferentiation and increased FGF2 expression initiate repair, but Del Rio-Tsonis and colleagues identify the importance of the RNA binding factor Lin28, which can direct the complete reprogramming of the RPE in this regeneration process in the chick eye.

    BMC Biology 2014, 12:28
  • Genetics of eye disorders in the dog

    Cathryn Mellersh looks at the mutations that have been associated with inherited eye disorders in the dog. Similarities between eye structure and disease in humans and dogs point to an increased role for dogs in helping us to understand and treat eye disorders in both species.

    Canine Genetics and Epidemiology 2014, 1:3
  • Every dog has its day: a new journal for canine genetics and epidemiology

    We are delighted to announce the launch of Canine Genetics and Epidemiology, an open access journal published by BioMed Central with the support and backing of the UK Kennel Club.

    Canine Genetics and Epidemiology 2014, 1:1
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    African microbiome research

    Leading researchers present their recommendations for harnessing microbiome and probiotic research in Sub-Saharan Africa.

    Microbiome 2014, 2:12
  • Image attributed to: From Rico et al.

    Gene expression in patient-derived xenografts

    Transcriptomic analysis shows for the first time that patient-derived xenografts in mice are more closely related to primary tumors than cell lines are for pancreatic tumors.

    Genome Medicine 2014, 6:27
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    We are pleased to announce that Women's Midlife Health is now accepting submissions.

    Women's Midlife Health is the first Open Access journal in the field of Menopause. The journal will publish original research and reviews on Menopause. It will cover other areas related to the physical and mental health of women during midlife, including aging, reproductive aging and their inter-relationship.

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    Cancer Imaging publishes its first articles with BioMed Central

    Cancer Imaging is the official journal of the International Cancer Imaging Society and publishes original articles, reviews and editorials written by expert international radiologists working in oncology.  The journal encompasses CT, MR, PET, ultrasound, radionuclide and multimodal imaging in all kinds of malignant tumours, plus new developments, techniques and innovations. 

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    Canine Genetics and Epidemiology has now launched

    BioMed Central is delighted to announce the lauch of Canine Genetics and Epidemiology. The journal will publish research and review articles on all aspects of canine genetics and epidemiology, with the support and backing of the Kennel Club, the UK’s largest organisation dedicated to the health and welfare of dogs.

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    Nuclear Receptor Signaling is now open for submissions

    BioMed Central is pleased to announce that Nuclear Receptor Signaling is now open for submissions. The journal has published reviews and commentaries with the Nuclear Receptor Signaling Atlas (NURSA) since 2004, but will now also consider primary research articles following its transfer.  The goal of NURSA is to accrue, develop, and communicate information that advances our understanding of the roles of nuclear receptors in human diseases and conditions in which they play an integral role. for further information please visit the journal.

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