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  • Head injury leads immune system to attack brain

    Traumatic brain injury causes selective, CD74-dependent peripheral lymphocyte activation that exacerbates neurodegeneration.

    Acta Neuropathologica Communications 2014, 2:143
  • Image attributed to: David, Wikimedia Commons

    Aging, metabolism and cancer

    David Gius and colleagues review the evidence that sirtiuns are tumor suppressor proteins that regulate mitochondrial metabolism, thereby linking aging mechanisms with carcinogenesis

    Cancer & Metabolism 2014, 2:15
  • Image attributed to: pixabay

    PDE5 inhibitors have cardioprotective effects

    Phosphodiesterase type 5 (PDE5) inhibitors are commonly used to treat erectile dysfunction; evidence from a meta-analysis suggests that these drugs also protect against cardiac remodelling, indicating that they could be used to treat heart disease.

    BMC Medicine 2014, 12:185
  • Image attributed to: Image credit: Alice Plane, BMC Biology

    Cancer cell signaling: What goes wrong?

    As the latest addition to our series of Open Questions, Steven Wiley focuses on the feedback controls on cell signaling and proliferation, and the need to understand how they are disrupted in cancer cells.

    BMC Biology 2014, 12:88
  • Image attributed to: Tietew, Wikimedia Commons

    Emerging picornaviruses in Hong Kong

    Human parechovirus, Aichi virus and salivirus were found in fecal samples from children in Hong Kong with gastroenteritis, providing the first information on the epidemiology of these emerging viruses in this region.

    Virology Journal 2014, 11:182
  • Image attributed to: iStock

    Visual impairment linked to comorbidities

    Patients over 65 years with visual impairment are more likely to have physical and mental comorbidities in comparison to their peers without visual impairment, indicating the need for specialized care to address individual needs in this patient group.

    BMC Medicine 2014, 12:181
  • Image attributed to: Wikipedia, CCMesserWoland

    Genes, environment & breast cancer

    Evidence suggests that gene-environment interactions could modify breast cancer risk; Olivia Fletcher and Frank Dudbridge discuss progress in elucidating these interactions, highlighting that further validation in large cohort studies is required.

    BMC Medicine 2014, 12:195
  • Not all cows are epidemiologically equal

    The authors investigated bovine viral diarrhoea virus (BVDV) transmission risk by combining statistical analysis of real serological data from surveyed beef and dairy herds with simulated data from a dynamic model.

    Veterinary Research 2014, 45:110
  • Image attributed to: wikimedia commons

    Limited diversity in AMA 1 malaria antigen

    Antigenic diversity of apical membrane antigen 1 (AMA1) in Plasmodium falciparum malaria is restricted to three alleles, suggesting that a multi-allele vaccine targeting limited AMA1 variants should confer protection against malaria.

    BMC Medicine 2014, 12:183
  • Image attributed to: Flickr CC (Tony Alter)

    Weight loss linked to HRQL in obese people

    In severely obese people, weight loss required for improvements in health-related quality of life (HRQL) is greater than conventional thresholds, and surgical treatment results in better HRQL, providing insights into effective weight loss strategies.

    BMC Medicine 2014, 12:175
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BioMed Central news

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    Eye and Vision has fully launched

    We are delighted to announce that Eye and Vision has now fully launched with BioMed Central and published its first articles.

    Eye and Vision, supported by Wenzhou Medical University, is an interdisciplinary journal which covers both ophthalmology and optometry. It aims to keep the ophthalmologists and visual science specialists up-to-date with the latest development in theoretical, experimental and clinical investigations in eye and vision. In doing so, it will promote the exchange of innovative ideas and advanced information worldwide.

    For more information please take a look at the launch editorial by Editor-in-Chief, Prof. Jia Qu. 

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    Fungal Biology and Biotechnology has launched

    We are pleased to announce that Fungal Biology and Biotechnology (FBB) has launched.

    FBB is our first dedicated fungal journal. It publishes articles on all aspects of fungal research from basic biology to applied science. Read the launch Editorial by the two Editors-in-Chief, Alexander Idnurm and Vera Meyer, a fantastic Review from Claudio Scazzocchio and the first published research articles.  

    Follow the social media campaign #fungalfortnight

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    Gynecologic Oncology Research and Practice has now launched

    We are pleased to announce that Gynecologic Oncology Research and Practice has published its first articles with BioMed Central.

    Edited by Robert L Coleman, Thomas J Herzog, and Bradley J Monk, Gynecologic Oncology Research and Practice is a new journal that publishes articles on the pathophysiology, prevention, diagnosis, and treatment of all cancers of the female reproductive system.

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    Tropical Diseases, Travel Medicine and Vaccines is now accepting submissions

    It is a pleasure to announce that Tropical Diseases, Travel Medicine and Vaccines is now accepting submissions.

    Tropical Diseases, Travel Medicine and Vaccines will publish basic, clinical and translational research and reviews related to the prevention and management of healthcare and diseases in international travelers. It is the first open access journal in the field of travel medicine and the first journal to focus on these three interrelated clinical specialties.

    The Editor in Chief is Mark Riddle, Commander in the Medical Corps of the United States Navy and board certified in General Public Health & Preventive Medicine. Cmdr. Riddle is also an Associate Editor of BMC Gastroenterology. He is joined by a distinguished editorial board of researchers and clinicians from all continents (except Antarctica).

    This journal is an excellent new addition to our infectious diseases portfolio.

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