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    Wheat sensitivity linked to bone loss

    Patients with non-celiac wheat sensitivity (NCWS) have higher incidence of osteoporosis than those with irritable bowel syndrome, and bone mass loss is associated with low body mass index, highlighting the need for dietary support in NCWS patients.

    BMC Medicine 2014, 12:230
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    Conserved cis-elements for stress response

    Striking conservation across jawed vertebrates is seen at the cis-regulatory level in the homeodomain transcription factor orthopedia (Otp) gene, involved in the regulation of hypothalamic neurons that are responsible for the stress response.

    BMC Developmental Biology 2014, 14:41
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    Stillbirth risk higher in males

    Evidence from a systematic review and meta-analysis of over 30 million births indicates that the risk of stillbirth in males is around 10% higher than in females, suggesting further research is required to understand the cause of excess male risk.

    BMC Medicine 2014, 12:220
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    Oral testosterone leads to CV risk

    Oral testosterone replacement therapy (TRT) leads to significant cardiovascular (CV) risk, whereas injected or transdermal TRT do not, which could be due to the different routes of administration, which might affect serum dihydrotestosterone.

    BMC Medicine 2014, 12:211
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    Protein unreliable to detect iron status

    Zinc protoporphyrin (ZPP) measured in blood has limited ability to identify iron deficiency in Kenyan pregnant women, and cannot reliably rule out the condition, suggesting that guidelines on the use of ZPP to assess iron status require revision.

    BMC Medicine 2014, 12:229
  • Image attributed to: Detail of Figure 3_from Tsalik et al.

    Expressed variants and sepsis outcomes

    Blood transcriptional profiling of patients with sepsis, including survivors and non-survivors, reveals survival is associated with a strong immune response and with missense variants in VPS9D1.

    Genome Medicine 2014, 6:111
  • Survival analysis tools in genomics research

    Survival analysis methodologies have been adapted to genomic analysis to link molecular information with clinical outcomes. Chen et al. provide an overview of currently available software, web applications and databases specifically developed for survival analysis in genomics research.

    Human Genomics 2014, 8:21
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    Going deep into the mitochondrial genome

    A new database, the most comprehensive and thorough analysis of mitochondrial gene content to date, has implications for the deep phylogeny of eukaryotes and provides an important resource for researchers in genome evolution.

    BMC Evolutionary Biology 2014, 14:237
  • How does our genome fold?

    Job Dekker proposes two ways the mammalian genome folds during the cell cycle, through insights obtained with chromosome conformation capture technology.

    Epigenetics & Chromatin 2014, 7:25
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    Yogurt linked to lower type 2 diabetes risk

    In a study of three large cohorts and a meta-analysis, total dairy intake is not associated with type 2 diabetes (T2D) incidence, but increased yogurt consumption is linked to reduced risk of T2D, suggesting that yogurt could have a protective effect.

    BMC Medicine 2014, 12:215
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    Climate Change Responses has now fully launched and has published its first articles

    An interdisciplinary journal dedicated to publishing exceptional research on ecological and evolutionary responses to climate change. The journal is especially interested in publishing ground-breaking work linking responses to environmental change across levels of biological organization, from individuals to ecosystems, and with an emphasis on species interactions.

    Read the interview with co-Editor-in-Chief, Frank Seebacher, to discover the aims and scope of Climate Change Responses and about Frank's own background as a research scientist. Find out more about the importance of studying the ecological impacts of climate change with co-Editor-in-Chief Eric Post interview with Biome

     

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    Journal of Compassionate Health Care (JCHC) has now fully launched

    This is the first open access journal that publishes leading research and perspectives in the growing field of compassionate health care. Read the Q+A with the Editors-in-Chief, Sue Shea and Christos Lionis, to find out more about the field and what they hope to achieve with the journal. 
    Click on the following links to dip into the first two research articles published and a case study by Robin Youngson, an international leader in compassionate healthcare.

     

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    Journal of Clinical Movement Disorders (JCMD) has now launched and published its first articles

    Edited by Dr Steven Frucht, JCMD focuses on scientific investigations into the diagnosis, evaluation and management of patients with involuntary movement disorders. The journal reviews, illustrates and emphasizes clinical phenomenology as an indispensable tool for the diagnosis and application of translational medicine to movement disorders. It also covers topics including Parkinson's disease, tremor, dystonia, myoclonus, Huntington's disease, tics, and pediatric movement disorders.

    For more information, please read the launch Editorial and an Editor Q&A with Dr Frucht published today in Biome.

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    Safety in Health is accepting submissions

    The journal encompasses global trends in healthcare affecting quality and safety. This includes patient safety, training and simulation, health economics, quality and process management, as well as critical incidents including the legal or regulatory aspects.

    For those wishing to submit a manuscript, click on the link for the instructions for authors and information about the journal's policies

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