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  • THS-Seq

    A transposome hypersensitive sites sequencing assay enables highly sensitive characterization of chromatin accessibility

    Genome Biology 2016, 17:20
  • lncRNA analysis across mammals

    An analysis of lncRNAs across mammals indicates these RNAs are a mixture of multiple functional classes with distinct biological roles

    Genome Biology 2016, 17:19
  • Epigenetics and cell differentiation

    A new study shows how a single cytokine regulates hematopoietic lineage choice by activating a pathway, which causes dendritic-cell-specific DNA demethylation

    Genome Biology 2016, 17:18
  • Proteome diversification by Alu

    A new study examines the input of Alu transposons into human genes

    Genome Biology 2016, 17:17
  • Variability of lncRNAs

    Long non-coding RNAs display higher natural expression variability than protein-coding genes in healthy humans

    Genome Biology 2016, 17:14
  • Alu exons and human proteins

    This article suggests that Alu elements have contributed to the acquisition of novel protein sequences during primate and human evolution

    Genome Biology 2016, 17:15
  • Cancer super-enhancer methylation

    Whole genome bisulfite sequencing in human cancers shows specific aberrant DNA methylation patterns at super-enhancers

    Genome Biology 2016, 17:11
  • Predicting pathogenic mutations

    This article describes an approach to indicate intolerant regions in functionally distinct portions of genes: exons and protein domains

    Genome Biology 2016, 17:9
  • TRIMs in plant genomes

    A comprehensive analysis of TRIM transposons in plant genomes provides new insights in to their distribution and evolution

    Genome Biology 2016, 17:7
  • Cytokine-mediated demethylation

    A novel role of IL-4 and its downstream pathway is revealed in demethylation of specific genes during human monocyte differentiation

    Genome Biology 2016, 17:4
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    The journalfocuses on a wide range of topics within neurology and neuroscience, including imaging in stroke, cranial vascular anatomy, and spine circulation. Read the latest articles and find out more about the journal, via this address http://www.nvijournal.com/

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    Tropical Medicine and Health is now open for submissions

    This is the official journal of the Japanese Society of Tropical Medicine. It publishes original research reviews on all aspects of tropical medicine and global health. If you've worked on clinical, epidemiological, laboratory or policy research, submit your article now.

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    European Review of Aging and Physical Activity (EURAPA) has launched

    This journal transferred to BioMed Central from Springer, having published as a subscription title since 2006. The relaunch was led by joint Editors-in-Chief Yael Netz (Israel), and Wiebren Zijlstra (Germany), and is published on behalf of the European Group for Research into Elderly and Physical Activity. EURAPA covers research on issues related to physical activity and aging across both biomedical and behavioral sciences. Visit the journal website to find out more.

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    Reproducibility: what are we going to do about it?

    As an increasing number of studies reveal that much of science is not able to be reproduced or replicated, BioMed Central launched the pilot of a new Minimum Standards of Reporting Checklist.

    The checklist addresses three areas of reporting: experimental design and statistics, resources, and availability of data and materials.

    As well as posting a blog to summarize the main features, a launch editorial was published, where BioMed Central staff and the Editors of GigaScience and Genome Biology stressed the need for ensuring the reproducibility of scientific work.

     

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