BioMed Central publishes 286 peer-reviewed open access journals.
Larger brain size in males is a pattern persisting throughout primate and human evolution; new experiments suggest a major role for estrogen in down-regulating genes linked to brain size, resulting in the smaller female brain size.
An exquisitely preserved fossil rhizome from a Jurassic era species of royal fern adds new morphological evidence to the controversial question of these plants evolutionary origins.
Steven LeVine and colleagues review the possible risks and benefits of using aspirin to reduce cardiovascular risk for multiple sclerosis (MS) patients, concluding that population-based studies are needed to establish guidance for aspirin use in MS.
A lipidomic study links lipodystrophy to relative increases in triglycerides associated with de novo lipogenesis, and suggests lipodomics as a useful biomarker of insulin resistance.
In an analysis of two randomized controlled trials evaluating the addition of local anesthetic wound infiltration (LAI) to standard analgesia after hip and knee replacement, LAI is cheaper than standard care, so could be a cost-effective treatment option.
The last ice age substantially shaped distributions of the spotted snow skink, a reptile found only in Tasmania, but in differing ways between north-western and south-eastern populations, patterns which could be replicated in other species.
Treating cancer in patients with learning disabilities can be challenging; Robert Huddart and colleagues discuss the management of testicular cancer in those with Down syndrome, concluding that a high cure rate can be achieved with appropriate therapy.
A bloom of cytochrome P450 encoding genes in the parsley family, resulting from a proliferation of gene duplications, gives insights into the evolution of chemicals crucial to plants in protecting themselves against insects.
Advantages over clinical exome sequencing can be achieved by using an NGS-based multiplexing assay involving comprehensive gene panels.
Abigail Caudle and Henry Kuerer review the management of lymph node metastases in breast cancer, highlighting that axillary lymph node dissection is no longer necessary in all patients, and discussing ways in which surgery could be reduced in the future.
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Big Data Analytics is now accepting submissions.
The journal aims to publish cutting-edge articles describing original basic and applied work involving biologically-inspired computational accounts of all aspects of big data science analytics.
The journal invites high-quality original research articles and timely reviews on current developments in the field, covering all aspects of big data analytics. Visit the journal website to find out why you should publish your article in Big Data Analytics.
Research Involvement and Engagement has published its first articles.
The new co-produced journal is both innovative and interdisciplinary. It is a health and social care journal that focuses on patient and wider involvement and engagement in research, at all stages.
All articles within the journal will be reviewed by both academics and patients, with both reports carrying equal weight in the editorial decision. The journal is led by two Editors-in-Chief –Sophie Staniszewska, PPI lead at RCN Research Institute, University of Warwick, UK, and Richard Stephens, an involved and engaged patient from the UK.
Read a fantastic piece on patient’s and clinicians’ priorities for research by Iain Chalmers and Sally Crowe.
Hereditas is now accepting submissions.
The journal was founded in 1920, hence it is one of the oldest journals in the field. It is the official publication of The Mendelian Society of Lund and transferred to BioMed Central this year.
Genes and Environment has published its first articles.