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  • Adipose tissue methylation

    A global DNA methylation analysis of obesity genes in adipose tissue before and after gastric bypass and weight loss

    Genome Biology 2015, 16:8
  • Image attributed to: Flickr: henry

    Limiting SBMU to 2 hours a day no longer feasible

    Current pediatric recommendations of less than 2 hours per day pertaining to screen based media use (SBMU) may no longer be tenable as SBM are central in the everyday lives of children and adolescents.

    BMC Public Health 2015, 15:5
  • How to study methylation throughout the genome?

    John Greally and Netha Ulahannan assess genome-wide assays to identify and quantify modified cytosines in human disease studies.

    Epigenetics & Chromatin 2015, 8:5
  • Image attributed to: iStock photos

    Is bacterial infection linked to back pain?

    Evidence from a systematic review suggests the presence of bacteria in spinal discs could be associated with low back pain and disc herniation, but more research is needed to determine whether low-grade infection contributes to chronic pain.

    BMC Medicine 2015, 13:13
  • Image attributed to: Rennett Stowe, CC2.0

    Chimps threatened by climate change

    Climate modelling projects that chimpanzee populations in central Cameroon will experience drastic reductions in suitable habitat over the course of this century; habitat for other West African populations is predicted to remain largely unchanged.

    BMC Evolutionary Biology 2015, 15:2
  • Image attributed to: istock

    Lithium therapy affects kidney function

    Duration of lithium therapy is associated with reduced kidney function regardless of subsequent discontinuation once kidneys are already damaged, suggesting that kidney risk should be weighed against lithium’s beneficial effects for mood disorders. 

    BMC Medicine 2015, 13:12
  • Changing views on morphogens

    James Briscoe discusses the role of Hedgehog as a graded morphogen signal in activating gene regulatory networks in the early patterning of the central nervous system, explaining how modeling can help.

    BMC Biology 2015, 13:5
  • Image attributed to: From Fig 1 Lettre and colleagues

    DNA methylation map in blood cell progenitors

    Comprehensive DNA methylome maps of human erythroblasts differentiated ex vivo from CD34+ progenitor cells purified from fetal liver or bone marrow reveal widespread dynamic changes during erythropoiesis.

    Genome Medicine 2015, 7:1
  • Image attributed to: istock

    Dietary patterns predict frailty risk

    In older adults, a prudent diet containing olive oil and vegetables is linked to lower risk of frailty whereas a Western diet is associated with frailty components, highlighting the need for trials to determine whether diet can protect against frailty.

    BMC Medicine 2015, 13:11
  • Image attributed to: istock photo

    MRA treatment beneficial for heart failure

    In a meta-analysis, treatment with mineralocorticoid receptor antagonists (MRAs) is linked to lower hospitalization rates for heart failure in patients with preserved systolic function, confirming the benefits of MRAs in these patients.

    BMC Medicine 2015, 13:10
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