No lizard lives at higher altitudes than P.erythrurus, which makes it home high on the Tibetan plateau; new research provides insights into the genetic changes this species has undergone to adapt to life in such a challenging environment.
DNMT1-dependent and –independent methylation patterns play distinct roles in mouse embryonic stem cell genome stability and transcriptional regulation
In an analysis of pregnant women undergoing non-invasive prenatal screening (NIPS), the positive predictive value for fetal chromosomal disorders is 77.4%, highlighting that abnormal results cannot be considered diagnostic and genetic testing should be offered.
In a systematic review of self-management interventions for asthma, effective strategies utilize a combination of patient engagement and training of healthcare professionals, indicating that self-management support should be implemented in clinical practice.
Patients with sepsis-associated acute respiratory distress syndrome (ARDS) on continuous statin therapy have lower 28-day mortality risk than those not taking statins, suggesting a survival benefit of statin therapy in this patient group.
The authors introduce two non-invasive methods for acquiring viable cells with primary cilia from ciliopathy patients, deriving cells from urine and milk teeth.
Roles for ZFP57-mediated regulation of genomic imprinting and a novel mechanism for genetically determined mono-allelic gene expression.
The Illumina MiSeq and MinION nanopore sequencer yield actionable clinical information on a Salmonella outbreak in less than half a day
Dexmedetomidine sedation during the nighttime can reduce the incidence of postoperative atrial fibrillation in cardiovascular surgery patients after tracheal extubation in ICU.
Parental smoking exacerbates poverty for a large proportion of children in the UK, suggesting tobacco control interventions which effectively enable low income smokers to quit can play an important role in reducing the financial burden of child poverty.
- Editor's picks in my subject areas
- Information for authors
- OA and developing world
- Information for librarians
- BioMed Central Members
- Information for advertisers
- Open Repository
- Publishing services
- Additional services
- Reasons to publish
- Press centre
- Social networks
- BioMed Central events
- Reprints and permissions
- Biome magazine