Articles

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  • Image attributed to: Public Domain

    How one lizard thrives on top of the world

    No lizard lives at higher altitudes than P.erythrurus, which makes it home high on the Tibetan plateau; new research provides insights into the genetic changes this species has undergone to adapt to life in such a challenging environment.

    BMC Evolutionary Biology 2015, 15:101
  • DNMT1-related methylation patterns

    DNMT1-dependent and –independent methylation patterns play distinct roles in mouse embryonic stem cell genome stability and transcriptional regulation

    Genome Biology 2015, 16:115
  • Image attributed to: pixabay

    Non-invasive prenatal screening not always accurate 

    In an analysis of pregnant women undergoing non-invasive prenatal screening (NIPS), the positive predictive value for fetal chromosomal disorders is 77.4%, highlighting that abnormal results cannot be considered diagnostic and genetic testing should be offered. 

    BMC Medicine 2015, 13:129
  • Image attributed to: istock photo

    Engagement improves asthma self-management

    In a systematic review of self-management interventions for asthma, effective strategies utilize a combination of patient engagement and training of healthcare professionals, indicating that self-management support should be implemented in clinical practice.

    BMC Medicine 2015, 13:127
  • Image attributed to: istock photo

    Statins linked to better survival in ARDS

    Patients with sepsis-associated acute respiratory distress syndrome (ARDS) on continuous statin therapy have lower 28-day mortality risk than those not taking statins, suggesting a survival benefit of statin therapy in this patient group.

    BMC Medicine 2015, 13:128
  • Non-invasive sources of cells with primary cilia

    The authors introduce two non-invasive methods for acquiring viable cells with primary cilia from ciliopathy patients, deriving cells from urine and milk teeth.

    Cilia 2015, 4:8
  • ZFP57 in imprinting

    Roles for ZFP57-mediated regulation of genomic imprinting and a novel mechanism for genetically determined mono-allelic gene expression.

    Genome Biology 2015, 16:112
  • Clinical nanopore sequencing

    The Illumina MiSeq and MinION nanopore sequencer yield actionable clinical information on a Salmonella outbreak in less than half a day

    Genome Biology 2015, 16:114
  • Dexmedetomidine reduces the incidence of AF

    Dexmedetomidine sedation during the nighttime can reduce the incidence of postoperative atrial fibrillation in cardiovascular surgery patients after tracheal extubation in ICU.

    Journal of Intensive Care 2015, 3:26
  • Image attributed to: Flickr:  Nikolai Vassiliev

    Smoking exacerbates child poverty

    Parental smoking exacerbates poverty for a large proportion of children in the UK, suggesting tobacco control interventions which effectively enable low income smokers to quit can play an important role in reducing the financial burden of child poverty.

    BMC Public Health 2015, 15:507
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