BioMed Central publishes 294 peer-reviewed open access journals.


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  • B. mandrillaris clinical metagenomics

    Sequencing and assembly of the Balamuthia mandrillaris genome allows metagenomic diagnosis in a case of encephalitis and underlines the importance of reference sequences.

    Genome Medicine 2015, 7:113
  • Treating sexually transmitted infections

    This Editorial sets the scene for the series in which we encounter the difficulties of treating antibiotic-resistant gonorrhoea and Mycoplasma genitalium; the continuing spread of chlamydia, syphilis and trichomoniasis, as well as management of non-gonococcal urethritis and bacterial vaginosis.

    BMC Infectious Diseases 2015, 15:337
  • Image attributed to: Detail of Figure 1 from Brown et al.

    Extracting TCR repertoires from RNA-seq data

    A novel analytical approach that allows extraction of T cell receptor sequence information directly from RNA sequencing data and that can be used to characterize tumor-associated T cell repertoires.

    Genome Medicine 2015, 7:125
  • Microbiome profiling from biopsies

    Doron Betel and colleagues describe methodology for the identification of pathogens from low bacterial abundance human WGS datasets

    Genome Biology 2015, 16:265
  • Image attributed to: iStock Photo

    PSA screening for prostate cancer

    Who and when to screen for prostate cancer using prostate-specific antigen (PSA) testing is highly controversial; in this forum article, Sigrid Carlsson and Andrew Vickers ask some of the world’s experts to discuss which men might benefit from screening.

    BMC Medicine 2015, 13:288
  • Supporting systematic reviews using LDA-based document representations

    Text mining methods to identify relevant studies during the screening stage of a systematic review are becoming more popular. During automatic citation screening, the LDA topic modelling approach results in a more informative representation of studies than the BOW model.

    Systematic Reviews 2015, 4:172
  • Image attributed to: Flickr cc European Commission/Martin Karimi

    Intervention measures reduce Ebola spread

    Transmission chain reconstruction modeling of an Ebola outbreak suggests containment of the disease depends on its natural history and intervention measures, arguing population awareness and strict compliance can strongly reduce widespread infection.

    BMC Medicine 2015, 13:281
  • Image attributed to: Flickr CC (DFID UK)

    NBC useful for defining cause of death

    The classic naive Bayes classifier (NBC) outperforms other automated classifiers for verbal autopsy when defining cause of death (COD), but further research is needed as no automated classifier adequately replicates physician classification of COD.

    BMC Medicine 2015, 13:286
  • Image attributed to: Influenza virus_from iStockPhoto

    B cell Rep-seq sheds light on Influenza immunity

    Longitudinal analysis of the B cell receptor repertoire after immunization with a new influenza virus strain reveals unique features in clonal structure, IGHV segment use and low somatic hypermutation levels.

    Genome Medicine 2015, 7:124
  • Down syndrome methylation

    Novel biological mechanisms are implicated in the development of Down syndrome by studying methylation patterns in humans and mice

    Genome Biology 2015, 16:263
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    Neurovascular Imaging has fully launched

    The journalfocuses on a wide range of topics within neurology and neuroscience, including imaging in stroke, cranial vascular anatomy, and spine circulation. Read the latest articles and find out more about the journal, via this address http://www.nvijournal.com/

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    Tropical Medicine and Health is now open for submissions

    This is the official journal of the Japanese Society of Tropical Medicine. It publishes original research reviews on all aspects of tropical medicine and global health. If you've worked on clinical, epidemiological, laboratory or policy research, submit your article now.

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    European Review of Aging and Physical Activity (EURAPA) has launched

    This journal transferred to BioMed Central from Springer, having published as a subscription title since 2006. The relaunch was led by joint Editors-in-Chief Yael Netz (Israel), and Wiebren Zijlstra (Germany), and is published on behalf of the European Group for Research into Elderly and Physical Activity. EURAPA covers research on issues related to physical activity and aging across both biomedical and behavioral sciences. Visit the journal website to find out more.

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    Reproducibility: what are we going to do about it?

    As an increasing number of studies reveal that much of science is not able to be reproduced or replicated, BioMed Central launched the pilot of a new Minimum Standards of Reporting Checklist.

    The checklist addresses three areas of reporting: experimental design and statistics, resources, and availability of data and materials.

    As well as posting a blog to summarize the main features, a launch editorial was published, where BioMed Central staff and the Editors of GigaScience and Genome Biology stressed the need for ensuring the reproducibility of scientific work.


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