Intrapleural mitoxantrone for the palliative treat...[Support Care Cancer. 1995]

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1: Support Care Cancer. 1995 Mar;3(2):147-9.Links

Intrapleural mitoxantrone for the palliative treatment of malignant pleural effusions.

Morales M, Expósito MC.

Department of Medicine, Hospital Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Canary Islands, Spain.

A group of 21 patients with malignant pleural effusions were treated with the instillation of 40 mg mitoxantrone intrapleurally, after complete fluid drainage. There was a 100% complete response rate with no toxic effects (0%). The mean survival of the patients was 57.1 weeks.

PMID: 7539702 [PubMed - indexed for MEDLINE]

Intrapericardial instillation of mitoxantrone in palliative therapy of malignant pericardial effusion. [Onkologie. 2003]
Prospective randomized trial of intrapleural bleomycin versus interferon alfa-2b via ultrasound-guided small-bore chest tube in the palliative treatment of malignant pleural effusions. [J Clin Oncol. 2004]
Intrapleurally instilled mitoxantrone in metastatic pleural effusions: a phase II study. [J Chemother. 1997]
Effects of intrapleural mitoxantrone and mepacrine on malignant pleural effusion--a randomised study. [Eur J Cancer. 1995]
Intrapleural and intraperitoneal palliative treatment of malignant effusions with mitoxantrone. [Anticancer Drugs. 1993]
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Intrapleural mitoxantrone for the palliative treatment of malignant pleural effusions.

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