A tetrodotoxin-producing Vibrio strain, LM-1, from...[Appl Environ Microbiol. 2000]

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1: Appl Environ Microbiol. 2000 Apr;66(4):1698-701. Links

Comment in:: Appl Environ Microbiol. 2001 May;67(5):2393-4.

A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus.

Lee MJ, Jeong DY, Kim WS, Kim HD, Kim CH, Park WW, Park YH, Kim KS, Kim HM, Kim DS.

Department of Diagnosis, Biochemistry and Molecular Biology, College of Oriental Medicine, Dongguk University, Kyung-Ju 780-714, Korea.

Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced TTX, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the toxification of the puffer fish.

PMID: 10742263 [PubMed - indexed for MEDLINE]

PMCID: PMC92044

Toxicity and distribution of tetrodotoxin-producing bacteria in puffer fish Fugu rubripes collected from the Bohai Sea of China. [Toxicon. 2005]
A new tetrodotoxin-producing actinomycete, Nocardiopsis dassonvillei, isolated from the ovaries of puffer fish Fugu rubripes. [Toxicon. 2005]
Reexamination of tetrodotoxin production by bacteria. [Appl Environ Microbiol. 1995]
Review[Recent advances in tetrodotoxin research] [Yakugaku Zasshi. 2000]
ReviewPuffer fish poisoning. [Am Fam Physician. 1990]

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A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus.

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