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There is a log-linear relationship of caries to sugar intake from 0% of energy intake (E) to 10%E sugar at where a costly burden of caries is induced, suggesting public health goals should set sugar intakes ideally less than 3%.
Peter Carmeliet reviews how metabolic pathways in endothelial cells regulate angiogenesis during cancer development, providing a hugely useful resource for the cancer metabolism field
Bronchial epithelial cells (BECs) from patients with Z variant alpha-1 antitrypsin (Z-AAT) deficiency, express and secrete Z-AAT and its polymers, suggesting that these cells are involved in the pathogenesis of emphysema and BEC dysfunction.
The Y-chromosome can be used for paternal demographic and lineage dating, however owing to naturally occuring mutations, results can be incaccurate. Looking into a solution for one of the biggest problems in Y-chromosome phylogenetic studies.
Eileen White discusses how cancer cells use autophagy to survive in low nutrient conditions and how new drugs targeting this process can be used to treat cancer.
Whole exome and whole genome sequencing has revealed specific mutations for various cancers, and so Eleftherios Diamandis suggests that the combination of genomics and proteomics may help to identify and develop clinically useful biomarkers.
Repression of mobile genetic elements is essential for the survival of germ cells. A new pathway for silencing LINE-1 elements is described by Donal O'Carroll and colleagues.
George Weinstock and colleagues analyze the double-stranded DNA virus genomes lurking in the wealth of data generated by the Human Microbiome Project, across multiple body habitats, individuals and timepoints.
While existing sloth species have relatively small body sizes, a phylogenetic analysis that includes fossil species suggests this is unrepresentative of long-term evolutionary trends in this group which were towards larger and larger body sizes.
In a comparison of four non-alcoholic fatty-liver disease (NAFLD) prediction scores, liver fat score (LFS) is the most robust in identifying NAFLD in an American population, suggesting LFS could be used to predict liver-related mortality.
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From the blog
- 16 September 2014
- Top-predator control does not always initiate trophic cascades
- 16 September 2014
- We are all sweet enough; it’s time for less sugar now
- 12 September 2014
- A new angiogenesis inhibitor targeting multiple tyrosine kinases offers new hope for treating tumors
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BioMed Central news
Porcine Health Management (PHM) is now accepting submissions.
BioMed is pleased to announce that this new society journal is accepting submissions. It is the official publication of the European Association for Porcine Health Management (EAPHM) and European College for Porcine Health Management (ECPHM). Both societies have institutional memberships with BioMed Central and will cover all article processing charges for their members.
PHM aims to cover all aspects of swine health medicine and production. This will include research on swine health and production, including infectious and non-infectious diseases, reproduction, epidemiology, management, economics, genetics, housing, nutrition, animal welfare and ethics, legislation, food safety, drugs and surgery.
The Editors-in-Chief of PHM are Stanley Done (just retired after a long career at the Animal Health and Veterinary Laboratories Agency UK) and Guy-Pierre Martineau, an experienced veterinarian at the French National Veterinary School in Toulouse, and the journal is supported by an international editorial board of swine experts.
Zoological Letters is now open for submissions.
Zoological Letters will publish important and valuable discoveries in various fields of zoology. The journal welcomes submissions of both basic and comparative zoology of broad interest to zoologists worldwide. As a sister journal to Zoological Science, Zoological Letters covers a wide range of basic fields of zoology, from taxonomy to bioinformatics.
Led by Editor-in-Chief Shigeru Kuratani, Center for Developmental Biology, RIKEN, the journal hopes to mirror and even surpass the success of its sister journal Zoological Science.
Journal of Animal Science and Technology has published its first articles with BioMed Central
The Journal of Animal Science and Technology publishes original research, review articles and notes in all fields of animal science. All article processing charges are covered by the journal, so authors don’t need to pay any APC.
Journal of Biological Research-Thessaloniki has now launched
We are pleased to announce that the Journal of Biological Research-Thessaloniki has now fully launched and has published its first articles. It is an international journal that publishes articles providing novel insights into the major fields of biology. Topics covered include molecular biology, cytology, genetics, evolutionary biology, morphology, development & differentiation, taxonomy, bioinformatics, physiology, marine biology, behaviour, ecology and conservation.