It is a challenge to assess whether rare and patient-specific mutations are cancer drivers. The algorithm DawnRank prioritizes altered genes on a single patient level.
A self-reported lack of physical activity was associated with shortened telomere length in early stage breast cancer survivors, suggesting a mechanism by which exercise can reduce cellular aging.
In a randomized trial, a community-based intervention aiming to prevent intimate partner violence (IPV) and HIV-risk behaviors in Uganda successfully reduced acceptance and incidence of IPV, and is now being delivered in other communities.
An integrated approach to predict and validate novel anti-cancer drug targets, with demonstration of strong anti-proliferative effects of predicted targets.
Jigisha Patel suggests current flaws within peer review systems in medical journals can be tackled by defining aims of peer review, offering training and recognition for reviewers, and providing readers with a way of identifying individual published articles that have been assessed by ‘trained’ reviewers.
Induced hypothermia after cardiac arrest does not alter immune response when compared with patients with a body temperature regulated at 36°C, contradicting fears that induced hypothermia may increase the risk of infection.
High throughput sequencing (HTS) for microbial forensics has the potential to solve crimes and enhance public safety, however, interpretation of the results relies on understanding the performance and limitations of HTS methods. Bruce Budowle and colleagues present new criteria to be considered for HTS validation for microbial forensics.
An analysis of the novel common TF binding site motif – zinger motif – reveals the need for careful analysis of ChIP-seq data
HIV-infected adults who have been using antiretroviral therapy for over two years have a higher incidence of hypertension compared with adults without HIV, indicating that screening measures should be targeted towards these patients.
The authors identified two significant risk factors associated with Chiari-like malformation/syringomyelia in the skull shape of the Cavalier King Charles Spaniel: extent of brachycephaly and distribution of doming of the cranium.
- Editor's picks in my subject areas
- Information for authors
- OA and developing world
- Information for librarians
- BioMed Central Members
- Information for advertisers
- Open Repository
- Publishing services
- Additional services
- Reasons to publish
- Press centre
- Social networks
- BioMed Central events
- Reprints and permissions
- Biome magazine