Combination of SMRT and Illumina reads provide comprehensive gene sets for newly sequenced genomes of non-model organisms sugar beet and spinach
Phenotype severity in mouse models of CRX-associated retinopathies correlates with graded gene expression changes
Glyn Elwyn et al. discuss the relationship between clinical practice guidelines for clinicians and decision support for patients, stressing that decision making in healthcare requires collaboration, and trustworthy evidence is needed for success.
Although patient and carer consultation in evidence-based medicine (EBM) has improved, Trish Greenhalgh et al. argue that biases, including power imbalances between patient and physician can hinder progress of EBM, and suggest ways in which these biases can be minimized.
Special issue guest editors Peter Fraser and David Gilbert discuss the state of the field and the articles in the issue
Oliver Cuvier discusses two recent Genome Biology articles which present methods for predicting aspects of nuclear organization from epigenetic data
Immunocompromised patients are at higher risk of contracting tuberculosis with atypical presentations. A 17 year-old man presented with focal fits progressing to epilepsia partialis continua. Mycobacterium tuberculosis was detected in the cerebrospinal fluid and successfully treated.
A method for predicting a sequence’s localization in the A or B compartment of the nucleus based on chromatin data
Part of a series on bioinformatics and systems biology in radiation oncology, this review looks at the promise of next-generation sequencing for developing personalised cancer treatment strategies.
In a systematic review, the inattentive component of attention deficit/hyperactivity disorder (ADHD) has a stronger negative association with mathematical ability than the hyperactive component, highlighting that ADHD domains could have differential etiology.
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