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  • SMRT sequencing in plants

    Combination of SMRT and Illumina reads provide comprehensive gene sets for newly sequenced genomes of non-model organisms sugar beet and spinach

    Genome Biology 2015, 16:184
  • Retinopathy phenotype severity

    Phenotype severity in mouse models of CRX-associated retinopathies correlates with graded gene expression changes

    Genome Biology 2015, 16:171
  • Image attributed to: istock

    Joint healthcare management

    Glyn Elwyn et al. discuss the relationship between clinical practice guidelines for clinicians and decision support for patients, stressing that decision making in healthcare requires collaboration, and trustworthy evidence is needed for success.

    BMC Medicine 2015, 13:199
  • Image attributed to: iStock photos

    Is EBM biased against patients?

    Although patient and carer consultation in evidence-based medicine (EBM) has improved, Trish Greenhalgh et al. argue that biases, including power imbalances between patient and physician can hinder progress of EBM, and suggest ways in which these biases can be minimized.

    BMC Medicine 2015, 13:200
  • 3Dome editorial

    Special issue guest editors Peter Fraser and David Gilbert discuss the state of the field and the articles in the issue

    Genome Biology 2015, 16:181
  • Predicting nuclear organization

    Oliver Cuvier discusses two recent Genome Biology articles which present methods for predicting aspects of nuclear organization from epigenetic data

    Genome Biology 2015, 16:182
  • Seizures in an immunocompromised youth

    Immunocompromised patients are at higher risk of contracting tuberculosis with atypical presentations. A 17 year-old man presented with focal fits progressing to epilepsia partialis continua. Mycobacterium tuberculosis was detected in the cerebrospinal fluid and successfully treated.

    Journal of Medical Case Reports 2015, 9:184
  • Predicting chromatin compartments

    A method for predicting a sequence’s localization in the A or B compartment of the nucleus based on chromatin data

    Genome Biology 2015, 16:180
  • Towards personalised radiation therapy

    Part of a series on bioinformatics and systems biology in radiation oncology, this review looks at the promise of next-generation sequencing for developing personalised cancer treatment strategies.

    Radiation Oncology 2015, 10:183
  • Image attributed to: flickr; doviende

    ADHD linked to mathematical ability

    In a systematic review, the inattentive component of attention deficit/hyperactivity disorder (ADHD) has a stronger negative association with mathematical ability than the hyperactive component, highlighting that ADHD domains could have differential etiology.

    BMC Medicine 2015, 13:204
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