Ottawa Hospital Research Institute, Canada
Skeletal Muscle is a peer-reviewed, open access, online journal that publishes articles investigating molecular mechanisms underlying the biology of skeletal muscle. A wide range of skeletal muscle biology is included: development, metabolism, the regulation of mass and function, aging, degeneration, dystrophy and regeneration. The emphasis is on understanding adult skeletal muscle, its maintenance, and its interactions with non-muscle cell types and regulatory modulators.
Skeletal Muscle is an exciting new journal that will provide a home for our field and facilitate better dissemination of our research.
After receiving his PhD from the University of Ottawa in 1988, Dr Rudnicki undertook post-doc work at Massachusetts Institute of Technology in the Whitehead Institute with Dr Rudolf Jaenisck. In 1992 he was appointed Assistant Professor at McMaster University, before joining the Ottawa Hospital Research Institute in 2000, where he is currently Senior Scientist and Director of the Regenerative Medicine Program and the Sprott Centre for Stem Cell Research. He is a Professor in the Department of Medicine at the University of Ottawa and is the Scientific Director of the Canadian Stem Cell Network.
Dr Rudnicki has published over 200 articles and has been awarded many honors, including the Canada Research Chair in Molecular Genetics (2001-current), and is an International Research Scholar of the Howard Hughes Medical Institute. He has been a Fellow of the Royal Society of Canada since 2006.
Dr Rudnicki's laboratory works to understand the molecular mechanisms that regulate the determination, proliferation, and differentiation of stem cells during embryonic development and during tissue regeneration. They identified Pax7 as a transcription factor required for the specification of satellite cells, and identified Wnt signaling as playing an important role in muscle stem cell function.