Joseph Buxbaum, PhD

Molecular Autism is a peer-reviewed, online open access journal that publishes high-quality basic, translational and clinical research that has relevance to the etiology, pathobiology, or treatment of autism and related neurodevelopmental conditions. Research that includes integration across levels is encouraged. Molecular Autism publishes empirical studies, reviews, and brief communications.

Director, Seaver Autism Center for Research and Treatment, Professor of Psychiatry, Neuroscience, and Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, United States of America.

Joseph Buxbaum is a world-renowned molecular geneticist and Director of the Seaver Autism Center and Professor at Mount Sinai School of Medicine. He heads the Laboratory of Molecular Neuropsychiatry, which has identified genes in autism and taken the findings of the causes of autism and translated them into animal models where therapeutic approaches can be evaluated. In this context, Professor Buxbaum has established the Autism Model Systems Initiative, which makes use of multiple experimental systems, to ultimately develop and evaluate novel therapeutics in autism spectrum conditions. He is a lead investigator in the Autism Genetics Consortium, the Autism Genome Project, and the Autism Case Control Cohort, and is a part of the Psychiatric Genetics Consortium.

Professor Buxbaum has received numerous awards for his research including recognition from the New York University Child Study Center (2004), from the American College of Neuropsychopharmacology (2005), and from the Eden Institute Foundation for his "commitment and dedication to improving the quality of life in individuals with autism" (2008).

Seaver Autism Center for Research and Treatment at Mount Sinai School of Medicine
Committed to Research. Dedicated to Care.

The Seaver Autism Center leads progressive research studies while providing comprehensive, personalized care to children and adults with autism spectrum conditions. Working together with you, we will identify the causes of autism and advance effective treatments.

The Seaver Autism Center for Research and Treatment was founded through the generous support of the Beatrice and Samuel A. Seaver Foundation.

SHANK3 and Phelan-McDermid Syndrome

Phelan-McDermid Syndrome (PMS) is a rare genetic syndrome in which one copy of the q13 portion of chromosome 22 is missing. The neurological and psychiatric phenotypes are due to loss of the SHANK3 gene contained in the q13 portion of chromosome 22. Mutations in the SHANK3 gene also produce a syndrome with the neurological and behavioral aspects of PMS. For more information and the latest research findings related to the SHANK3 gene and Phelan-McDermid Syndrome, please visit www.shank3gene.org.

Co-Editor of The Neuroscience of Autism Spectrum Disorders.