Sanford-Burnham Medical Research Institute, United States of America
Molecular Neurodegeneration is an open access, peer-reviewed online journal that encompasses all aspects of neurodegeneration research at the molecular and cellular levels.
Huaxi Xu, Ph.D., is Professor and Acting Director of the Degenerative Disease Program at Sanford-Burnham Medical Research Institute. His research focuses on molecular events underlying the pathogenesis of Alzheimer’s disease (AD) and Down Syndrome (DS) integrating genetic, neurobiological, molecular and cellular information to clarify the biology of beta-amyloid precursor protein and other important genes/proteins, as well as the mechanisms by which mutant genes alter these proteins’ abilities in regulating neuronal functions and cause AD and DS.
Dr. Xu received his Ph.D. in 1993 with Dr. Dennis Shields in the areas of prohormone processing, vesicle biogenesis and sorting in the secretory pathway, from Albert Einstein College of Medicine. He conducted his postdoctoral research in the area of neural signal transduction in the laboratory of Paul Greengard at The Rockefeller University. In 1998, Dr. Xu was appointed Assistant Professor at The Rockefeller University, followed by Associate Professor in 2003. He was then appointed as Professor in 2008 at the Sanford-Burnham Medical Research Institute.