Guojun Bu

 Guojun Bu

Mayo Clinic, United States of America

Find publications in PubMed

Molecular Neurodegeneration is an open access, peer-reviewed online journal that encompasses all aspects of neurodegeneration research at the molecular and cellular levels.

Dr. Bu is a Professor at Washington University School of Medicine. He is an acknowledged leader in the field of apoE receptor biology. Dr. Bu has made major contributions to the understanding of LRP1 function in the CNS and his seminal work has defined the role of LRP1 in APP trafficking and abeta/apoE metabolism. Work from his lab published in 2007 in Neuron discovered a role of APP in apoE and cholesterol metabolism, and for the first time linking genetic determinants of early and late-onset AD. Dr. Bu obtained his undergraduate degree from the Beijing Normal University in China. He then studied biochemistry and molecular biology in the Department of Biochemistry at Virginia Tech as a CUSBEA fellow where he received his Ph.D