Aravind, L
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA

Articles published by BioMed Central

Discovery notes    
Novel eukaryotic enzymes modifying cell-surface biopolymers
Anantharaman V, Aravind L
Biology Direct 2010, 5:1 (7 January 2010)
[Abstract] [Provisional PDF]

Discovery notes    
The Anabaena sensory rhodopsin transducer defines a novel superfamily of prokaryotic small-molecule binding domains
De Souza RF, Iyer LM, Aravind L
Biology Direct 2009, 4:25 (14 August 2009)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles] [2 comments]

Research    
Reconstructing the ubiquitin network - cross-talk with other systems and identification of novel functions
Venancio TM, Balaji S, Iyer LM, Aravind L
Genome Biology 2009, 10:R33 (30 March 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Discovery notes    
A new family of polymerases related to superfamily A DNA polymerases and T7-like DNA-dependent RNA polymerases
Iyer LM, Abhiman S, Aravind L
Biology Direct 2008, 3:39 (4 October 2008)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research article    
Differences in evolutionary pressure acting within highly conserved ortholog groups
Przytycka TM, Jothi R, Aravind L, Lipman DJ
BMC Evolutionary Biology 2008, 8:208 (17 July 2008)
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Editorial    
Opening Pandora's Box: making biological discoveries through computational data exploration
Aravind L
Biology Direct 2007, 2:29 (20 November 2007)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research    
Small but versatile: the extraordinary functional and structural diversity of the -grasp fold
Burroughs AM, Balaji S, Iyer LM, Aravind L
Biology Direct 2007, 2:18 (2 July 2007)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research article    
Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive assessment
Jothi R, Przytycka TM, Aravind L
BMC Bioinformatics 2007, 8:173 (23 May 2007)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research    
A novel superfamily containing the -grasp fold involved in binding diverse soluble ligands
Burroughs AM, Balaji S, Iyer LM, Aravind L
Biology Direct 2007, 2:4 (24 January 2007)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research    
The signaling helix: a common functional theme in diverse signaling proteins
Anantharaman V, Balaji S, Aravind L
Biology Direct 2006, 1:25 (5 September 2006)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research    
The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like -grasp domains
Iyer LM, Burroughs AM, Aravind L
Genome Biology 2006, 7:R60 (19 July 2006)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research    
Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels
Tasneem A, Iyer LM, Jakobsson E, Aravind L
Genome Biology 2004, 6:R4 (20 December 2004)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Novel conserved domains in proteins with predicted roles in eukaryotic cell-cycle regulation, decapping and RNA stability
Anantharaman V, Aravind L
BMC Genomics 2004, 5:45 (16 July 2004)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research    
A novel family of P-loop NTPases with an unusual phyletic distribution and transmembrane segments inserted within the NTPase domain
Aravind L, Iyer LM, Leipe DD, Koonin EV
Genome Biology 2004, 5:R30 (16 April 2004)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research    
New connections in the prokaryotic toxin-antitoxin network: relationship with the eukaryotic nonsense-mediated RNA decay system
Anantharaman V, Aravind L
Genome Biology 2003, 4:R81 (26 November 2003)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research    
The two faces of Alba: the evolutionary connection between proteins participating in chromatin structure and RNA metabolism
Aravind L, Iyer LM, Anantharaman V
Genome Biology 2003, 4:R64 (8 September 2003)
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Research article    
Application of comparative genomics in the identification and analysis of novel families of membrane-associated receptors in bacteria
Anantharaman V, Aravind L
BMC Genomics 2003, 4:34 (12 August 2003)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Ancient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteins
Iyer LM, Anantharaman V, Aravind L
BMC Genomics 2003, 4:5 (3 February 2003)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research    
Evolutionary history, structural features and biochemical diversity of the NlpC/P60 superfamily of enzymes
Anantharaman V, Aravind L
Genome Biology 2003, 4:R11 (3 February 2003)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases
Iyer LM, Koonin EV, Aravind L
BMC Structural Biology 2003, 3:1 (28 January 2003)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
The catalytic domains of thiamine triphosphatase and CyaB-like adenylyl cyclase define a novel superfamily of domains that bind organic phosphates
Iyer LM, Aravind L
BMC Genomics 2002, 3:33 (27 November 2002)
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Research    
The PRC-barrel: a widespread, conserved domain shared by photosynthetic reaction center subunits and proteins of RNA metabolism
Anantharaman V, Aravind L
Genome Biology 2002, 3:research0061.1-research0061.9 (14 October 2002)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research    
The SWIRM domain: a conserved module found in chromosomal proteins points to novel chromatin-modifying activities
Aravind L, Iyer LM
Genome Biology 2002, 3:research0039.1-research0039.7 (24 July 2002)
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Research    
The GOLD domain, a novel protein module involved in Golgi function and secretion
Anantharaman V, Aravind L
Genome Biology 2002, 3:research0023.1-research0023.7 (24 April 2002)
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Research article    
Classification and evolutionary history of the single-strand annealing proteins, RecT, Red, ERF and RAD52
Iyer LM, Koonin EV, Aravind L
BMC Genomics 2002, 3:8 (21 March 2002)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research    
Extensive domain shuffling in transcription regulators of DNA viruses and implications for the origin of fungal APSES transcription factors
Iyer LM, Koonin EV, Aravind L
Genome Biology 2002, 3:research0012.1-research0012.11 (13 February 2002)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research    
The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases
Aravind L, Koonin EV
Genome Biology 2001, 2:research0007.1-research0007.8 (19 February 2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research    
The alpha/beta fold uracil DNA glycosylases: a common origin with diverse fates
Aravind L, Koonin EV
Genome Biology 2000, 1:research0007.1-research0007.8 (13 October 2000)
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