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76.

2841
Accesses

Research   Open Access Highly Accessed

Long-term effects of low-fat diets either low or high in protein on cardiovascular and metabolic risk factors: a systematic review and meta-analysis

Lukas Schwingshackl, Georg Hoffmann Nutrition Journal 2013, 12:48 (15 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

77.

2810
Accesses

Research   Open Access Highly Accessed

Improvement in coronary heart disease risk factors during an intermittent fasting/calorie restriction regimen: Relationship to adipokine modulations

Cynthia M Kroeger, Monica C Klempel, Surabhi Bhutani, John F Trepanowski, Christine C Tangney, Krista A Varady Nutrition & Metabolism 2012, 9:98 (31 October 2012)

Abstract | Full text | PDF | PubMed

78.

2807
Accesses

Research   Open Access Highly Accessed

Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group

Rinaldo Bellomo, Claudio Ronco, John A Kellum, Ravindra L Mehta, Paul Palevsky, the ADQI workgroup Critical Care 2004, 8:R204-R212 (24 May 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment | F1000

79.

2801
Accesses

Research   Open Access Highly Accessed

The health impacts of globalisation: a conceptual framework

Maud MTE Huynen, Pim Martens, Henk BM Hilderink Globalization and Health 2005, 1:14 (3 August 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

80.

2788
Accesses

Research   Open Access

Continuous on-line glucose measurement by microdialysis in a central vein. A pilot study

Christina Blixt, Olav Rooyackers, Bengt Isaksson, Jan Wernerman Critical Care 2013, 17:R87 (11 May 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

A potential new tool for intravascular continuous glucose monitoring in intensive care patients could prevent hypoglycaemia or high glucose variability. 

81.

2784
Accesses

Research   Open Access Highly Accessed

How to interpret the transmissibility of novel influenza A(H7N9): an analysis of initial epidemiological data of human cases from China

Hiroshi Nishiura, Kenji Mizumoto, Keisuke Ejima Theoretical Biology and Medical Modelling 2013, 10:30 (4 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

82.

2719
Accesses

Research   Open Access Highly Accessed

Noninvasive ventilation immediately after extubation improves weaning outcome after acute respiratory failure: a randomized controlled trial

Susana R Ornico, Suzana M Lobo, Helder S Sanches, Maristela Deberaldini, Luciane T Tófoli, Ana M Vidal, Guilherme P Schettino, Marcelo B Amato, Carlos R Carvalho, Carmen S Barbas Critical Care 2013, 17:R39 (4 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A randomized controlled trial shows that non-invasive ventilation applied immediately after extubation prevents re-intubation and decreases hospital mortality when compared to oxygen mask therapy.

83.

2713
Accesses

Case Report   Open Access Highly Accessed

Torsion of ovarian cyst during pregnancy: a case report

Vasavi Kolluru, Rekha Gurumurthy, Venkatasujatha Vellanki, Deshpande Gururaj Cases Journal 2009, 2:9405 (31 December 2009)

Abstract | Full text | PDF | PubMed

84.

2697
Accesses

Research article   Open Access Highly Accessed

Effect of an electronic nicotine delivery device (e-Cigarette) on smoking reduction and cessation: a prospective 6-month pilot study

Riccardo Polosa, Pasquale Caponnetto, Jaymin B Morjaria, Gabriella Papale, Davide Campagna, Cristina Russo BMC Public Health 2011, 11:786 (11 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

85.

2683
Accesses

Method   Open Access Highly Accessed

jMOSAiCS: joint analysis of multiple ChIP-seq datasets

Xin Zeng, Rajendran Sanalkumar, Emery H Bresnick, Hongda Li, Qiang Chang, Sunduz Keles Genome Biology 2013, 14:R38 (29 April 2013)

Abstract | Provisional PDF |  Editor’s summary

A novel probabilistic method for jointly analyzing multiple ChIP-seq datasets offers an improvement over chromHMM

86.

2685
Accesses

Review   Open Access Highly Accessed

Weight Science: Evaluating the Evidence for a Paradigm Shift

Linda Bacon, Lucy Aphramor Nutrition Journal 2011, 10:9 (24 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

87.

2659
Accesses

Review   Subscription Highly Accessed

Clinical review: Does it matter which hemodynamic monitoring system is used?

Davinder Ramsingh, Brenton Alexander, Maxime Cannesson Critical Care 2012, 17:208 (5 March 2013)

Abstract | Full text | PDF

88.

2600
Accesses

Research   Open Access Highly Accessed

Systematic biases in DNA copy number originate from isolation procedures

Sebastiaan van Heesch, Michal Mokry, Veronika Boskova, Wade Junker, Rajdeep Mehon, Pim Toonen, Ewart de Bruijn, James D Shull, Timothy J Aitman, Edwin Cuppen, Victor Guryev Genome Biology 2013, 14:R33 (24 April 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

A new study pinpoints the sources of copy number variation biases, highlighting the important issue of sample preparation

89.

2593
Accesses

Review   Open Access Highly Accessed

Toxic epidermal necrolysis and Stevens-Johnson syndrome

Thomas Harr, Lars E French Orphanet Journal of Rare Diseases 2010, 5:39 (16 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

90.

2575
Accesses

Review   Open Access Highly Accessed

Nutrition and cancer: A review of the evidence for an anti-cancer diet

Michael S Donaldson Nutrition Journal 2004, 3:19 (20 October 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

91.

2569
Accesses

Research article   Open Access Highly Accessed

Effects of supplemental fish oil on resting metabolic rate, body composition, and salivary cortisol in healthy adults

Eric E Noreen, Michael J Sass, Megan L Crowe, Vanessa A Pabon, Josef Brandauer, Lindsay K Averill Journal of the International Society of Sports Nutrition 2010, 7:31 (8 October 2010)

Abstract | Full text | PDF | PubMed

92.

2546
Accesses

Research   Open Access Highly Accessed

Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing

Jason O'Rawe, Tao Jiang, Guangqing Sun, Yiyang Wu, Wei Wang, Jingchu Hu, Paul Bodily, Lifeng Tian, Hakon Hakonarson, W Evan Johnson, Zhi Wei, Kai Wang, Gholson J Lyon Genome Medicine 2013, 5:28 (27 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Head-to-head comparison of widely used variant calling pipelines including SOAP, GATK and Complete Genomics using default parameters reveals discrepancies between the pipelines.

93.

2537
Accesses

Research article   Open Access Highly Accessed

Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium

Fabienne Meier-Abt, Emanuela Milani, Tim Roloff, Heike Brinkhaus, Stephan Duss, Dominique S Meyer, Ina Klebba, Piotr J Balwierz, Erik van Nimwegen, Mohamed Bentires-Alj Breast Cancer Research 2013, 15:R36 (29 April 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Early parity in mice alters the genomic signature of a distinct subset of mammary epithelial cells by inducing differentiation and reducing proliferation, ultimately protecting against breast cancer.

94.

2530
Accesses

Research   Open Access Highly Accessed

Volumetric three-dimensional intravascular ultrasound visualization using shape-based nonlinear interpolation

Yonghoon Rim, David D McPherson, Hyunggun Kim BioMedical Engineering OnLine 2013, 12:39 (7 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

95.

2529
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Commentary   Open Access Highly Accessed

Somatic and visceral nervous systems - an ancient duality

Paola Bertucci, Detlev Arendt BMC Biology 2013, 11:54 (30 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The idea that vertebrates are composed of a ‘visceral’ and ‘somatic’ self, responding to internal and external stimuli, respectively, was first put forward in the 19th century. Now, molecular fingerprinting indicates a duality between the somatic and visceral nervous systems that appears to predate Bilataria.

96.

2511
Accesses

Research   Open Access Highly Accessed

Consumption of low-fat dairy foods for 6 months improves insulin resistance without adversely affecting lipids or bodyweight in healthy adults: a randomized free-living cross-over study

Todd C Rideout, Christopher P F Marinangeli, Heather Martin, Richard W Browne, Curtis B Rempel Nutrition Journal 2013, 12:56 (2 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

97.

2486
Accesses

Research   Open Access Highly Accessed

Renaissance of base deficit for the initial assessment of trauma patients: a base deficit-based classification for hypovolemic shock developed on data from 16,305 patients derived from the TraumaRegister DGU®

Manuel Mutschler, Ulrike Nienaber, Thomas Brockamp, Arasch Wafaisade, Tobias Fabian, Thomas Paffrath, Bertil Bouillon, Marc Maegele, the TraumaRegister DGU Critical Care 2013, 17:R42 (6 March 2013)

Abstract | Full text | PDF | PubMed | 1 comment |  Editor’s summary

Base deficit (BD)-based shock classification better discriminates the need for early blood transfusion and mortality in severely injured patients than the current Advanced Trauma Life Support (ATLS) protocol.

98.

2488
Accesses

Technical advance   Open Access Highly Accessed

A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants

Tanis R Fenton, Jae H Kim BMC Pediatrics 2013, 13:59 (20 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

The Fenton growth chart for preterm infants has been revised to accommodate the World Health Organization Growth Standard and reflect actual age instead of completed weeks, in order to improve preterm infant growth monitoring.

99.

2482
Accesses

Research   Open Access Highly Accessed

Modeling of electric field distribution in tissues during electroporation

Selma Corovic, Igor Lackovic, Primoz Sustaric, Tomaz Sustar, Tomaz Rodic, Damijan Miklavcic BioMedical Engineering OnLine 2013, 12:16 (21 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

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