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	1. 13226 Accesses	Research article scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs Gregory R Leong, Karen R Goulding, Nancy Amin, Helena E Richardson, Anthony M Brumby BMC Biology 2009, 7:62 (24 September 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary Scribble, a cell polarity regulator in Drosophila, represses tumorigenesis by inhibiting atypical protein kinase C and Jun N-terminal kinase-dependent pathways, and this might be relevant for how human Scrib restrains oncogene-mediated transformation.
	2. 13205 Accesses	Research article Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes Mari Palgi, Dario Greco, Riitta Lindström, Petri Auvinen, Tapio I Heino BMC Genomics 2012, 13:134 (11 April 2012) Abstract \| Full text \| PDF \| PubMed
	3. 9441 Accesses	Method TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions Daehwan Kim, Geo Pertea, Cole Trapnell, Harold Pimentel, Ryan Kelley, Steven L Salzberg Genome Biology 2013, 14:R36 (25 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A major update to TopHat, the popular Bowtie-based spliced aligner
	4. 9065 Accesses	Review Nutrient timing revisited: is there a post-exercise anabolic window? Alan Albert Aragon, Brad Jon Schoenfeld Journal of the International Society of Sports Nutrition 2013, 10:5 (29 January 2013) Abstract \| Full text \| PDF \| PubMed
	5. 8930 Accesses	Research article Love thy neighbour: facilitation through an alternative signalling modality in plants Monica Gagliano, Michael Renton BMC Ecology 2013, 13:19 (7 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Chilli seedlings germinate better when grown in the presence of ‘good neighbour’ plants like basil even when all forms of chemical and visual signals are blocked, suggesting that an as-yet unidentified system of communication exists between plants.
	6. 7848 Accesses	Research article A phylogeny and revised classification of Squamata, including 4161 species of lizards and snakes Robert Alexander Pyron, Frank T Burbrink, John J Wiens BMC Evolutionary Biology 2013, 13:93 (29 April 2013) Abstract \| Provisional PDF \| PubMed
	7. 7429 Accesses	Research article Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition Sabine Rohrmann, Kim Overvad, H Bueno-de-Mesquita, Marianne U Jakobsen, Rikke Egeberg, Anne Tjønneland, Laura Nailler, Marie-Christine Boutron-Ruault, Françoise Clavel-Chapelon, Vittorio Krogh, Domenico Palli, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Manuela M Bergmann, Heiner Boeing, Kuanrong Li, Rudolf Kaaks, Kay-Tee Khaw, Nicholas J Wareham, Francesca L Crowe, Timothy J Key, Androniki Naska, Antonia Trichopoulou, Dimitirios Trichopoulos, Max Leenders, Petra HM Peeters, Dagrun Engeset, Christine L Parr, Guri Skeie et al. BMC Medicine 2013, 11:63 (7 March 2013) Abstract \| Full text \| PDF \| PubMed \| 2 comments \| Editor’s summary A large study finds a positive association between processed meat consumption and mortality due to cardiovascular disease and cancer, indicating that reducing the amount of processed meat in the diet could reduce mortality risk.
	8. 7164 Accesses	Editorial Raymond Gosling: the man who crystallized genes Naomi Attar Genome Biology 2013, 14:402 (25 April 2013) Abstract \| Full text \| PDF \| PubMed \| 1 comment \| Editor’s summary "The most wonderful thing!" - Genome Biology meets Raymond Gosling, a key player in the discovery of the double helix
	9. 6961 Accesses	Comment After the gold rush Neil Hall Genome Biology 2013, 14:115 (7 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Neil Hall wonders whether genomics is ready for a plateau in sequencing costs
	10. 6720 Accesses	Research Management of bleeding and coagulopathy following major trauma: an updated European guideline Donat R Spahn, Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Daniela Filipescu, Beverley J Hunt, Radko Komadina, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Jean-Louis Vincent, Rolf Rossaint Critical Care 2013, 17:R76 (19 April 2013) Abstract \| Provisional PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The Task Force for Advanced Bleeding Care in Trauma have updated their guidelines on the management of bleeding following traumatic injury, with new recommendations addressing changes made in clinical care.
	11. 6343 Accesses	Research Article Inferring the potential risks of H7N9 infection by spatiotemporally characterizing bird migration and poultry distribution in eastern China Benyun Shi, Shang Xia, Guo-Jing Yang, Xiao-Nong Zhou, Jiming Liu Infectious Diseases of Poverty 2013, 2:8 (3 May 2013) Abstract \| Full text \| PDF \| Editor’s summary In view of the rapid geographic spread and increased number of confirmed cases of novel influenza A(H7N9) virus infections in eastern China, this study develops a model to characterize the impacts of bird migration and poultry distribution on the geographic spread of the infection.
	12. 6268 Accesses	Research article Depression, antidepressant medications, and risk of Clostridium difficile infection Mary A M Rogers, M Todd Greene, Vincent B Young, Sanjay Saint, Kenneth M Langa, John Y Kao, David M Aronoff BMC Medicine 2013, 11:121 (7 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The risk of Clostridium difficile infection is increased in adults with depression and in those taking antidepressants during hospitalization, indicating that physicians should be aware of the elevated infection risk in these patients.
	13. 6154 Accesses	Review Childhood obesity, prevalence and prevention Mahshid Dehghan, Noori Akhtar-Danesh, Anwar T Merchant Nutrition Journal 2005, 4:24 (2 September 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments
	14. 5578 Accesses	Opinion Sixty years of genome biology W Doolittle, Peter Fraser, Mark B Gerstein, Brenton R Graveley, Steven Henikoff, Curtis Huttenhower, Alicia Oshlack, Chris P Ponting, John L Rinn, Michael C Schatz, Jernej Ule, Detlef Weigel, George M Weinstock Genome Biology 2013, 14:113 (25 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Members of Genome Biology's Editorial Board select their highlights from the 60 years of genome biology that followed the double helix
	15. 5654 Accesses	Research Efficacy of a meal replacement diet plan compared to a food-based diet plan after a period of weight loss and weight maintenance: a randomized controlled trial Lisa M Davis, Christopher Coleman, Jessica Kiel, Joni Rampolla, Tammy Hutchisen, Laura Ford, Wayne S Andersen, Andrea Hanlon-Mitola Nutrition Journal 2010, 9:11 (11 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	16. 5616 Accesses	Research article A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers Michael A Quail, Miriam Smith, Paul Coupland, Thomas D Otto, Simon R Harris, Thomas R Connor, Anna Bertoni, Harold P Swerdlow, Yong Gu BMC Genomics 2012, 13:341 (24 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Sequencing of four microbial genomes with widely differing GC content is compared on performance using three major new platforms: Ion Torrent PGM, Pacific Biosciences RS, and illumina MiSeq versus Illumina HiSeq system.
	17. 5596 Accesses	Comment How to evaluate a graduate studentship, or choosing the right doctoral advisor Duncan T Odom Genome Biology 2013, 14:114 (29 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Duncan Odom has some sage advice for those considering PhD options
	18. 5592 Accesses	Research Genome of the long-living sacred lotus (Nelumbo nucifera Gaertn.) Ray Ming, Robert VanBuren, Yanling Liu, Mei Yang, Yuepeng Han, Lei-Ting Li, Qiong Zhang, Min-Jeong Kim, Michael C Schatz, Michael Campbell, Jingping Li, John E Bowers, Haibao Tang, Eric Lyons, Ann A Ferguson, Giuseppe Narzisi, David R Nelson, Crysten E Blaby-Haas, Andrea R Gschwend, Yuannian Jiao, Joshua P Der, Fanchang Zeng, Jennifer Han, Xiang Jia Min, Karen A Hudson, Ratnesh Singh, Aleel K Grennan, Steven J Karpowicz, Jennifer R Watling, Kikukatsu Ito et al. Genome Biology 2013, 14:R41 (10 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary The genome of the long-living, slowly evolving sacred lotus reveals the genetic mechanisms underlying its adaptation to limited nutrient availability
	19. 5392 Accesses	Review Food Advertising and Marketing Directed at Children and Adolescents in the US Mary Story, Simone French International Journal of Behavioral Nutrition and Physical Activity 2004, 1:3 (10 February 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	20. 5339 Accesses	Review Physical education, school physical activity, school sports and academic performance François Trudeau, Roy J Shephard International Journal of Behavioral Nutrition and Physical Activity 2008, 5:10 (25 February 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	21. 5273 Accesses	Research The importance of human resources management in health care: a global context Stefane M Kabene, Carole Orchard, John M Howard, Mark A Soriano, Raymond Leduc Human Resources for Health 2006, 4:20 (27 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	22. 5196 Accesses	Research A novel virus genome discovered in an extreme environment suggests recombination between unrelated groups of RNA and DNA viruses Geoffrey S Diemer, Kenneth M Stedman Biology Direct 2012, 7:13 (19 April 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The discovery of a previously unknown viral genome, the apparent result of a recombination event between unrelated RNA and DNA viruses, has implications for theories of viral evolution.
	23. 4797 Accesses	Review Dietary protein intake and renal function William F Martin, Lawrence E Armstrong, Nancy R Rodriguez Nutrition & Metabolism 2005, 2:25 (20 September 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	24. 4613 Accesses	Opinion Spectrum of gluten-related disorders: consensus on new nomenclature and classification Anna Sapone, Julio C Bai, Carolina Ciacci, Jernej Dolinsek, Peter HR Green, Marios Hadjivassiliou, Katri Kaukinen, Kamran Rostami, David S Sanders, Michael Schumann, Reiner Ullrich, Danilo Villalta, Umberto Volta, Carlo Catassi, Alessio Fasano BMC Medicine 2012, 10:13 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Fasano and colleagues propose new nomenclature and classifications within the spectrum of gluten-related disorders (GRDs), prompted by indications from the past decade that reactions to gluten may be caused by conditions other than celiac disease.
	25. 4597 Accesses	Debate A theory of organizational readiness for change Bryan J Weiner Implementation Science 2009, 4:67 (19 October 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	26. 4587 Accesses	Research article Does long-term creatine supplementation impair kidney function in resistance-trained individuals consuming a high-protein diet? Rebeca Lugaresi, Marco Leme, Vítor de Salles Painelli, Igor Murai, Hamilton Roschel, Marcelo Sapienza, Antonio Lancha Junior, Bruno Gualano Journal of the International Society of Sports Nutrition 2013, 10:26 (16 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary More evidence to show that creatine is safe.
	27. 4520 Accesses	Review Ketogenic diets and physical performance Stephen D Phinney Nutrition & Metabolism 2004, 1:2 (17 August 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	28. 4468 Accesses	Research The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage John Abramyan, Daleen Badenhorst, Kyle K Biggar, Glen M Borchert, Christopher W Botka, Rachel M Bowden, Edward L Braun, Anne M Bronikowski, Benoit G Bruneau, Leslie T Buck, Blanche Capel, Todd A Castoe, Mike Czerwinski, Kim D Delehaunty, Scott V Edwards, Catrina C Fronick, Matthew K Fujita, Lucinda Fulton, Tina A Graves, Richard E Green, Wilfried Haerty, Ramkumar Hariharan, LaDeana H Hillier, Alisha K Holloway, Daniel Janes, Fredric J Janzen, Cyriac Kandoth, Lesheng Kong, Jason de Koning, Yang Li et al. Genome Biology 2013, 14:R28 (28 March 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary The genome of the western painted turtle, Chrysemys picta bellii, reveals insights into its extreme tolerance to anoxia and freezing
	29. 4354 Accesses	Research Prenatal and perinatal analgesic exposure and autism: an ecological link Ann Z Bauer, David Kriebel Environmental Health 2013, 12:41 (9 May 2013) Abstract \| Provisional PDF \| PubMed
	30. 4271 Accesses	Research Nuclear war between Israel and Iran: lethality beyond the pale Cham E Dallas, William C Bell, David J Stewart, Antonio Caruso, Frederick M Burkle, Jr Conflict and Health 2013, 7:10 (10 May 2013) Abstract \| Provisional PDF \| PubMed
	31. 4189 Accesses	Method Quartz-Seq: a highly reproducible and sensitive single-cell RNA-Seq reveals non-genetic gene expression heterogeneity Yohei Sasagawa, Itoshi Nikaido, Tetsutaro Hayashi, Hiroki Danno, Kenichiro D Uno, Takeshi Imai, Hiroki R Ueda Genome Biology 2013, 14:R31 (17 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Quartz-Seq is a method for performing single cell RNA-seq which displays high reproducibility
	32. 3973 Accesses	Research Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels Yanning Zheng, Qiang Liu, Lingling Li, Wen Qin, Jianming Yang, Haibo Zhang, Xinglin Jiang, Tao Cheng, Wei Liu, Xin Xu, Mo Xian Biotechnology for Biofuels 2013, 6:57 (24 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	33. 3991 Accesses	Research The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice Marguerite Prior, Richard Dargusch, Jennifer L Ehren, Chandramouli Chiruta, David Schubert Alzheimer's Research & Therapy 2013, 5:25 (14 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Novel drug candidate J147 is able to arrest and reverse memory deficits and improve several aspects of brain function in aged mice with advanced symptoms of Alzheimer's disease (AD).
	34. 3888 Accesses	Review ISSN exercise & sport nutrition review: research & recommendations Richard B Kreider, Colin D Wilborn, Lem Taylor, Bill Campbell, Anthony L Almada, Rick Collins, Mathew Cooke, Conrad P Earnest, Mike Greenwood, Douglas S Kalman, Chad M Kerksick, Susan M Kleiner, Brian Leutholtz, Hector Lopez, Lonnie M Lowery, Ron Mendel, Abbie Smith, Marie Spano, Robert Wildman, Darryn S Willoughby, Tim N Ziegenfuss, Jose Antonio Journal of the International Society of Sports Nutrition 2010, 7:7 (2 February 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	35. 3883 Accesses	Research The burden of non communicable diseases in developing countries Abdesslam Boutayeb, Saber Boutayeb International Journal for Equity in Health 2005, 4:2 (14 January 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	36. 3702 Accesses	Research Slower immune system aging in women versus men in the Japanese population Katsuiku Hirokawa, Masanori Utsuyama, Yoshio Hayashi, Masanobu Kitagawa, Takashi Makinodan, Tamas Fulop Immunity & Ageing 2013, 10:19 (15 May 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The female's immune system declines at a slower rate than the male's during ageing, contributing (in part) to the significantly longer life expectancy found in women, compared to men.
	37. 3638 Accesses	Research article Amniotic fluid embolism incidence, risk factors and outcomes: a review and recommendations Marian Knight, Cynthia Berg, Peter Brocklehurst, Michael Kramer, Gwyneth Lewis, Jeremy Oats, Christine L Roberts, Catherine Spong, Elizabeth Sullivan, Jos van Roosmalen, Joost Zwart BMC Pregnancy and Childbirth 2012, 12:7 (10 February 2012) Abstract \| Full text \| PDF \| PubMed
	38. 3496 Accesses	Review Critical care management of severe traumatic brain injury in adults Samir H Haddad, Yaseen M Arabi Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012, 20:12 (3 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	39. 3483 Accesses	Research article A comparison of methods for differential expression analysis of RNA-seq data Charlotte Soneson, Mauro Delorenzi BMC Bioinformatics 2013, 14:91 (9 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	40. 3460 Accesses	Research Body weight status and cardiovascular risk factors in adults by frequency of candy consumption Mary M Murphy, Leila M Barraj, Xiaoyu Bi, Nicolas Stettler Nutrition Journal 2013, 12:53 (30 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	41. 3445 Accesses	Correspondence Mistaken Identifiers: Gene name errors can be introduced inadvertently when using Excel in bioinformatics Barry R Zeeberg, Joseph Riss, David W Kane, Kimberly J Bussey, Edward Uchio, W Marston Linehan, J Carl Barrett, John N Weinstein BMC Bioinformatics 2004, 5:80 (23 June 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 7 comments
	42. 3436 Accesses	Commentary International Society of Sports Nutrition position stand: protein and exercise Bill Campbell, Richard B Kreider, Tim Ziegenfuss, Paul La Bounty, Mike Roberts, Darren Burke, Jamie Landis, Hector Lopez, Jose Antonio Journal of the International Society of Sports Nutrition 2007, 4:8 (26 September 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	43. 3424 Accesses	Research A survey of energy drink consumption patterns among college students Brenda M Malinauskas, Victor G Aeby, Reginald F Overton, Tracy Carpenter-Aeby, Kimberly Barber-Heidal Nutrition Journal 2007, 6:35 (31 October 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	44. 3414 Accesses	Commentary The Hospital Anxiety And Depression Scale R Philip Snaith Health and Quality of Life Outcomes 2003, 1:29 (1 August 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	45. 3397 Accesses	Research CRISPR-Cas systems target a diverse collection of invasive mobile genetic elements in human microbiomes Quan Zhang, Mina Rho, Haixu Tang, Thomas G Doak, Yuzhen Ye Genome Biology 2013, 14:R40 (29 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Analysis of CRISPR sequences contained in human metagenomic datasets reveals a variety of different targeted mobile genetic elements
	46. 3383 Accesses	Technical advance A new growth chart for preterm babies: Babson and Benda's chart updated with recent data and a new format Tanis R Fenton BMC Pediatrics 2003, 3:13 (16 December 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	47. 3299 Accesses	Review A novel coronavirus capable of lethal human infections: an emerging picture Gulfaraz Khan Virology Journal 2013, 10:66 (28 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary This timely review summarises the ongoing outbreak of a novel coronavirus (HCoV-EMC), which has caused a number of fatal cases in the UK and Middle East.
	48. 3192 Accesses	Research article Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women Hector L Lopez, Tim N Ziegenfuss, Jennifer E Hofheins, Scott M Habowski, Shawn M Arent, Joseph P Weir, Arny A Ferrando Journal of the International Society of Sports Nutrition 2013, 10:22 (19 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	49. 3247 Accesses	Research Detection of the valvular split within the second heart sound using the reassigned smoothed pseudo Wigner-Ville distribution Abdelghani Djebbari, Fethi Bereksi-Reguig BioMedical Engineering OnLine 2013, 12:37 (30 April 2013) Abstract \| Provisional PDF \| PubMed
	50. 3246 Accesses	Research article Ancient origin of somatic and visceral neurons Marc Nomaksteinsky, Stefan Kassabov, Zoubida Chettouh, Henri-Corto Stoeklé, Laure Bonnaud, Gilles Fortin, Eric R Kandel, Jean-François Brunet BMC Biology 2013, 11:53 (30 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The great American palaeontologist and anatomist Alfred Romer speculated that early in animal life, an emerging somatic nervous system, focused on the outside world, struggled to dominate the visceral nervous system that takes care of the internal systems that keep us alive. Jean-François Brunet and colleagues identify the molecular signatures that tell the evolutionary tale of this duality.