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1.

Research article   Open Access

Markers of thrombogenesis are activated in unmedicated patients with acute psychosis: a matched case control study

Jiří Masopust, Radovan Malý, Ctirad Andrýs, Martin Vališ, Jan Bažant, Ladislav Hosák BMC Psychiatry 2011, 11:2 (3 January 2011)

Abstract | Full text | PDF | PubMed | 1 comment

2.

Commentary   Open Access Highly Accessed

Language acquisition for deaf children: Reducing the harms of zero tolerance to the use of alternative approaches

Tom Humphries, Poorna Kushalnagar, Gaurav Mathur, Donna Napoli, Carol Padden, Christian Rathmann, Scott R Smith Harm Reduction Journal 2012, 9:16 (2 April 2012)

Abstract | Full text | PDF | PubMed

3.

Debate   Open Access Highly Accessed

Knowledge translation within a population health study: how do you do it?

Alison Kitson, Kathryn Powell, Elizabeth Hoon, Jonathan Newbury, Anne Wilson, Justin Beilby Implementation Science 2013, 8:54 (21 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

4.

Methodology   Open Access Highly Accessed

Stool substitute transplant therapy for the eradication of Clostridium difficile infection: ‘RePOOPulating’ the gut

Elaine O Petrof, Gregory B Gloor, Stephen J Vanner, Scott J Weese, David Carter, Michelle C Daigneault, Eric M Brown, Kathleen Schroeter, Emma Allen-Vercoe Microbiome 2013, 1:3 (9 January 2013)

Abstract | Full text | PDF |  Editor’s summary

A super-probiotic synthetic stool, composed of 33 different bacterial strains, was developed and used to treat two patients with severe C. difficile infection. The probiotic bacteria could still be detected up to six months after inoculation.

5.

Research   Open Access

Energy intakes of US children and adults by food purchase location and by specific food source

Adam Drewnowski, Colin D Rehm Nutrition Journal 2013, 12:59 (8 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

6.

Study protocol   Open Access

Barriers and facilitators of adherence to medical advice on skin self-examination during melanoma follow-up care

Annett Körner, Martin Drapeau, Brett D Thombs, Zeev Rosberger, Beatrice Wang, Manish Khanna, Alan Spatz, Adina Coroiu, Rosalind Garland, Gerald Batist BMC Dermatology 2013, 13:3 (1 March 2013)

Abstract | Full text | PDF | PubMed

7.

Review   Open Access Highly Accessed

Gene regulation by the act of long non-coding RNA transcription

Aleksandra E Kornienko, Philipp M Guenzl, Denise P Barlow, Florian M Pauler BMC Biology 2013, 11:59 (30 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Florian Pauler, Denise Barlow and colleagues review the evidence on long non-protein-coding RNAs for which the process of transcription itself functions in the regulation of nearby genes, but the RNA product may be irrelevant.

8.

Research article   Open Access Highly Accessed

Human milk metagenome: a functional capacity analysis

Tonya L Ward, Sergey Hosid, Ilya Ioshikhes, Illimar Altosaar BMC Microbiology 2013, 13:116 (25 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

9.

Research   Open Access Highly Accessed

Guideline adaptation and implementation planning: a prospective observational study

Margaret B Harrison, Ian D Graham, Joan van den Hoek, Elizabeth J Dogherty, Meg E Carley, Valerie Angus Implementation Science 2013, 8:49 (8 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

10.

Research article   Open Access Highly Accessed

N-acetylcysteine does not prevent contrast nephropathy in patients with renal impairment undergoing emergency CT: a randomized study

Pierre-Alexandre Poletti, Alexandra Platon, Sophie De Seigneux, Elise Dupuis-Lozeron, François Sarasin, Christoph D Becker, Thomas Perneger, Patrick Saudan, Pierre-Yves Martin BMC Nephrology 2013, 14:119 (3 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

11.

Research   Open Access Highly Accessed

Management of bleeding and coagulopathy following major trauma: an updated European guideline

Donat R Spahn, Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Daniela Filipescu, Beverley J Hunt, Radko Komadina, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Jean-Louis Vincent, Rolf Rossaint Critical Care 2013, 17:R76 (19 April 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The Task Force for Advanced Bleeding Care in Trauma have updated their guidelines on the management of bleeding following traumatic injury, with new recommendations addressing changes made in clinical care.

12.

Debate   Open Access Highly Accessed

Toward the future of psychiatric diagnosis: the seven pillars of RDoC

Bruce N Cuthbert, Thomas R Insel BMC Medicine 2013, 11:126 (14 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Bruce Cuthbert and Thomas Insel argue that future psychiatric nosologies will be informed by the Research Domain Criteria (RDoC) that is based on genetics, neuroscience and behavioural science, which will help achieve precision medicine for mental disorders.

13.

Research article   Open Access Highly Accessed

Depression, antidepressant medications, and risk of Clostridium difficile infection

Mary A M Rogers, M Todd Greene, Vincent B Young, Sanjay Saint, Kenneth M Langa, John Y Kao, David M Aronoff BMC Medicine 2013, 11:121 (7 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The risk of Clostridium difficile infection is increased in adults with depression and in those taking antidepressants during hospitalization, indicating that physicians should be aware of the elevated infection risk in these patients.

14.

Opinion   Open Access Highly Accessed

Spectrum of gluten-related disorders: consensus on new nomenclature and classification

Anna Sapone, Julio C Bai, Carolina Ciacci, Jernej Dolinsek, Peter HR Green, Marios Hadjivassiliou, Katri Kaukinen, Kamran Rostami, David S Sanders, Michael Schumann, Reiner Ullrich, Danilo Villalta, Umberto Volta, Carlo Catassi, Alessio Fasano BMC Medicine 2012, 10:13 (7 February 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Fasano and colleagues propose new nomenclature and classifications within the spectrum of gluten-related disorders (GRDs), prompted by indications from the past decade that reactions to gluten may be caused by conditions other than celiac disease.

15.

Research   Open Access

Evaluation of three industrial Escherichia coli strains in fed-batch cultivations during high-level SOD protein production

Karoline Marisch, Karl Bayer, Monika Cserjan-Puschmann, Markus Luchner, Gerald Striedner Microbial Cell Factories 2013, 12:58 (11 June 2013)

Abstract | Provisional PDF | PubMed

16.

Review   Open Access Highly Accessed

Management of imported malaria in Europe

Helena H Askling, Fabrice Bruneel, Gerd Burchard, Francesco Castelli, Peter L Chiodini, Martin P Grobusch, Rogelio Lopez-Vélez, Margaret Paul, Eskild Petersen, Corneliu Popescu, Michael Ramharter, Patricia Schlagenhauf, on behalf of the European Society for Clinical Microbiology and Infectious Diseases Study Group on Clinical Parasitology Malaria Journal 2012, 11:328 (17 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A very comprehensive review on imported malaria and recommendation for its management.

17.

Commentary   Open Access Highly Accessed

It is time to rethink tactics in the fight against malaria

Laurence Slutsker, S Kachur Malaria Journal 2013, 12:140 (24 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

On world malaria day, renowned malariologists from CDC discuss dangers and resilience, despite successful control in many areas, and how we may need to rethink our strategy in order to defeat the parasite.

18.

Database   Open Access Highly Accessed

PMTED: a plant microRNA target expression database

Xiuli Sun, Boquan Dong, Lingjie Yin, Rongzhi Zhang, Wei Du, Dongfeng Liu, Nan Shi, Aili Li, Yanchun Liang, Long Mao BMC Bioinformatics 2013, 14:174 (3 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

19.

Research article   Open Access Highly Accessed

Protein complex detection using interaction reliability assessment and weighted clustering coefficient

Nazar Zaki, Dmitry Efimov, Jose Berengueres BMC Bioinformatics 2013, 14:163 (20 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

20.

Short report   Open Access Highly Accessed

Carbohydrate mouth rinse: does it improve endurance exercise performance?

Vitor Painelli, Humberto Nicastro, Antonio H Lancha Nutrition Journal 2010, 9:33 (27 August 2010)

Abstract | Full text | PDF | PubMed

21.

Research   Open Access

pLDH level of clinically isolated Plasmodium vivax and detection limit of pLDH based malaria rapid diagnostic test

Jin Jang, Chi Cho, Eun Han, Seong Soo A An, Chae Lim Malaria Journal 2013, 12:181 (3 June 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

pLDH-detecting RDTs are widely used for diagnosing non-P. falciparum human Plasmodium infections and their performance vary. Factors such as genetic diversity of pLDH and antigen levels of pLDH could contribute to variations in sensitivities of pLDH RDTs. THis study adds to our knowledge on such issues.

22.

Research   Open Access Highly Accessed

Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men

Kjetil Berge, Fabiana Piscitelli, Nils Hoem, Cristoforo Silvestri, Ingo Meyer, Sebastiano Banni, Vincenzo Di Marzo Lipids in Health and Disease 2013, 12:78 (27 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

23.

Review   Open Access Highly Accessed

The "impact factor" revisited

Peng Dong, Marie Loh, Adrian Mondry Biomedical Digital Libraries 2005, 2:7 (5 December 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

Research article   Open Access Highly Accessed

Hypervariable antigen genes in malaria have ancient roots

Martine M Zilversmit, Ella K Chase, Donald S Chen, Philip Awadalla, Karen P Day, Gil McVean BMC Evolutionary Biology 2013, 13:110 (31 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

25.

Research article   Open Access

The two tryptophans of β2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure

Sara Raimondi, Nicola Barbarini, Palma Mangione, Gennaro Esposito, Stefano Ricagno, Martino Bolognesi, Irene Zorzoli, Loredana Marchese, Cristina Soria, Riccardo Bellazzi, Maria Monti, Monica Stoppini, Mario Stefanelli, Paolo Magni, Vittorio Bellotti BMC Evolutionary Biology 2011, 11:159 (10 June 2011)

Abstract | Full text | PDF | PubMed

26.

Analytic Perspective   Open Access Highly Accessed

The missed lessons of Sir Austin Bradford Hill

Carl V Phillips, Karen J Goodman Epidemiologic Perspectives & Innovations 2004, 1:3 (4 October 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

27.

Research   Open Access

Measured and perceived environmental characteristics are related to accelerometer defined physical activity in older adults

Scott J Strath, Michael J Greenwald, Raymond Isaacs, Teresa L Hart, Elizabeth K Lenz, Christopher J Dondzila, Ann M Swartz International Journal of Behavioral Nutrition and Physical Activity 2012, 9:40 (3 April 2012)

Abstract | Full text | PDF | PubMed

28.

Review   Open Access Highly Accessed

Food Advertising and Marketing Directed at Children and Adolescents in the US

Mary Story, Simone French International Journal of Behavioral Nutrition and Physical Activity 2004, 1:3 (10 February 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

29.

Research   Open Access

Ten principles of good interdisciplinary team work

Susan A Nancarrow, Andrew Booth, Steven Ariss, Tony Smith, Pam Enderby, Alison Roots Human Resources for Health 2013, 11:19 (10 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

30.

Review   Open Access Highly Accessed

The Quality of Life Scale (QOLS): Reliability, Validity, and Utilization

Carol S Burckhardt, Kathryn L Anderson Health and Quality of Life Outcomes 2003, 1:60 (23 October 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

31.

Research   Open Access

Reduced fractional shortening of right ventricular outflow tract is associated with adverse outcomes in patients with left ventricular dysfunction

Masashi Yamaguchi, Toshihiro Tsuruda, Yuki Watanabe, Hisamitsu Onitsuka, Kuniko Furukawa, Takeshi Ideguchi, Junji Kawagoe, Tetsunori Ishikawa, Johji Kato, Makoto Takenaga, Kazuo Kitamura Cardiovascular Ultrasound 2013, 11:19 (3 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

32.

Study protocol   Open Access

Evaluating the effectiveness of reasoning training in military and civilian chronic traumatic brain injury patients: study protocol

Daniel C Krawczyk, Carlos Marquez de la Plata, Guido F Schauer, Asha K Vas, Molly Keebler, Stephanie Tuthill, Claire Gardner, Tiffani Jantz, Weikei Yu, Sandra B Chapman Trials 2013, 14:29 (30 January 2013)

Abstract | Full text | PDF | PubMed

33.

Study protocol   Open Access

An oral health intervention for people with serious mental illness (Three Shires Early Intervention Dental Trial): study protocol for a randomised controlled trial

Hannah F Jones, Clive E Adams, Andrew Clifton, Jayne Simpson, Graeme Tosh, Peter F Liddle, Patrick Callaghan, Min Yang, Boliang Guo, Vivek Furtado Trials 2013, 14:158 (29 May 2013)

Abstract | Full text | PDF | PubMed

34.

Study protocol   Open Access Highly Accessed

Implementing the ten steps to successful breastfeeding in multiple hospitals serving low-wealth patients in the US: innovative research design and baseline findings

Miriam H Labbok, Emily C Taylor, Nathan C Nickel International Breastfeeding Journal 2013, 8:5 (20 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

35.

Review   Open Access Highly Accessed

Nanotechnology-based drug delivery systems

Sarabjeet Suri, Hicham Fenniri, Baljit Singh Journal of Occupational Medicine and Toxicology 2007, 2:16 (1 December 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

36.

Research article   Open Access Highly Accessed

The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild

Javier Prado-Martinez, Irene Hernando-Herraez, Belen Lorente-Galdos, Marc Dabad, Oscar Ramirez, Carlos Baeza-Delgado, Carlos Morcillo-Suarez, Can Alkan, Fereydoun Hormozdiari, Emanuele Raineri, Jordi Estellé, Marcos Fernandez-Callejo, Mònica Valles, Lars Ritscher, Torsten Schöneberg, Elisa de la Calle-Mustienes, Sònia Casillas, Raquel Rubio-Acero, Marta Melé, Johannes Engelken, Mario Caceres, Jose Gomez-Skarmeta, Marta Gut, Jaume Bertranpetit, Ivo G Gut, Teresa Abello, Evan E Eichler, Ismael Mingarro, Carles Lalueza-Fox, Arcadi Navarro, Tomas Marques-Bonet et al. BMC Genomics 2013, 14:363 (31 May 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

A phenotypically unique gorilla carries a private non-synonymous substitution in a transmembrane domain in SLC45A2, one of the candidate genes associated with the OCA4 class of albinism

37.

Short paper   Open Access Highly Accessed

Reduced orbitofrontal cortical thickness in male adolescents with internet addiction

Soon-Beom Hong, Jae-Won Kim, Eun-Jung Choi, Ho-Hyun Kim, Jeong-Eun Suh, Chang-Dai Kim, Paul Klauser, Sarah Whittle, Murat Yűcel, Christos Pantelis, Soon-Hyung Yi Behavioral and Brain Functions 2013, 9:11 (12 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

38.

Research   Open Access

Proteomic analysis of the cerebrospinal fluid of patients with restless legs syndrome/Willis-Ekbom disease

Stephanie M Patton, Yong Cho, Thomas W Clardy, Richard P Allen, Christopher J Earley, James R Connor Fluids and Barriers of the CNS 2013, 10:20 (7 June 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

A protein profile of people with restless leg syndrome identifies factors behind disrupted sleep, cardiovascular dysfunction and pain, giving insights into the disorder, which could prove useful in the development of new treatments.

39.

Review   Open Access Highly Accessed

Control of blood glucose in type 2 diabetes without weight loss by modification of diet composition

Mary C Gannon, Frank Q Nuttall Nutrition & Metabolism 2006, 3:16 (23 March 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 3 comments

40.

Research   Open Access

Inhibition of Hazara nairovirus replication by small interfering RNAs and their combination with ribavirin

Olivier Flusin, Solenne Vigne, Christophe N Peyrefitte, Michèle Bouloy, Jean-Marc Crance, Frédéric Iseni Virology Journal 2011, 8:249 (21 May 2011)

Abstract | Full text | PDF | PubMed

41.

Research article   Open Access

Identifying frailty: do the Frailty Index and Groningen Frailty Indicator cover different clinical perspectives? a cross-sectional study

Irene Drubbel, Nienke Bleijenberg, Guido Kranenburg, René JC Eijkemans, Marieke J Schuurmans, Niek J de Wit, Mattijs E Numans BMC Family Practice 2013, 14:64 (21 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

42.

Correspondence   Open Access

Systematically reviewing and synthesizing evidence from conversation analytic and related discursive research to inform healthcare communication practice and policy: an illustrated guide

Ruth H Parry, Victoria Land BMC Medical Research Methodology 2013, 13:69 (30 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

43.

Debate   Open Access

The Perioperative Surgical Home: how can it make the case so everyone wins?

Thomas R Vetter, Lee A Goeddel, Arthur M Boudreaux, Thomas R Hunt, Keith A Jones, Jean-Francois Pittet BMC Anesthesiology 2013, 13:6 (14 March 2013)

Abstract | Full text | PDF | PubMed

44.

Question and Answer   Open Access Highly Accessed

Q&A: Antibiotic resistance: what more do we know and what more can we do?

Gerard D Wright BMC Biology 2013, 11:51 (17 May 2013)

Full text | PDF | PubMed |  Editor’s summary

Antibiotic resistance is both an ancient phenomenon and a worsening medical problem. Gerard Wright explains why, and what should be done about it.

45.

Research   Open Access

In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines

Ping Wang, Zhenhe Suo, Mengyu Wang, Hanne K Høifødt, Øystein Fodstad, Gustav Gaudernack, Gunnar Kvalheim Experimental Hematology & Oncology 2013, 2:16 (6 June 2013)

Abstract | Provisional PDF | PubMed

46.

Research   Open Access

Ultra-deep sequencing enables high-fidelity recovery of biodiversity for bulk arthropod samples without PCR amplification

Xin Zhou, Yiyuan Li, Shanlin Liu, Qing Yang, Xu Su, Lili Zhou, Min Tang, Ribei Fu, Jiguang Li, Quanfei Huang GigaScience 2013, 2:4 (27 March 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

A new PCR-free sequencing-based method for metabarcoding provides new tools for studying eukaryotic biodiversity and gain quantitative taxonomic information from a DNA-soup extracted from bulk arthropod samples

47.

Review   Open Access

The maintenance and monitoring of perioperative blood volume

Takehiko Iijima, Birgitte Brandstrup, Peter Rodhe, Audrius Andrijauskas, Christer H Svensen Perioperative Medicine 2013, 2:9 (7 May 2013)

Abstract | Full text | PDF | ePUB

48.

Review   Open Access

Anaerobic threshold, is it a magic number to determine fitness for surgery?

Paul Older Perioperative Medicine 2013, 2:2 (21 February 2013)

Abstract | Full text | PDF | ePUB

49.

Research   Open Access

A qualitative study into the difficulties experienced by healthcare decision makers when reading a Cochrane diagnostic test accuracy review

Zhivko Zhelev, Ruth Garside, Christopher Hyde Systematic Reviews 2013, 2:32 (16 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

50.

Review   Open Access Highly Accessed

Combination therapy in hypertension: An update

Sanjay Kalra, Bharti Kalra, Navneet Agrawal Diabetology & Metabolic Syndrome 2010, 2:44 (24 June 2010)

Abstract | Full text | PDF | PubMed

51.

Review   Open Access Highly Accessed

Critical care management of severe traumatic brain injury in adults

Samir H Haddad, Yaseen M Arabi Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012, 20:12 (3 February 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

52.

Review   Open Access Highly Accessed

Intestinal microbiota, probiotics and mental health: from Metchnikoff to modern advances: Part I – autointoxication revisited

Alison C Bested, Alan C Logan, Eva M Selhub Gut Pathogens 2013, 5:5 (18 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

53.

Review   Open Access Highly Accessed

Effectiveness of interventions in reducing pain and maintaining physical activity in children and adolescents with calcaneal apophysitis (Sever’s disease): a systematic review

Alicia M James, Cylie M Williams, Terry P Haines Journal of Foot and Ankle Research 2013, 6:16 (3 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

54.

Review   Open Access Highly Accessed

Nutrient timing revisited: is there a post-exercise anabolic window?

Alan Albert Aragon, Brad Jon Schoenfeld Journal of the International Society of Sports Nutrition 2013, 10:5 (29 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A different look at the science of nutrient timing.

55.

Research   Open Access Highly Accessed

Nuclear war between Israel and Iran: lethality beyond the pale

Cham E Dallas, William C Bell, David J Stewart, Antonio Caruso, Frederick M Burkle, Jr Conflict and Health 2013, 7:10 (10 May 2013)

Abstract | Full text | PDF | PubMed

56.

Case report   Open Access

Dystrophinopathy presenting with arrhythmia in an asymptomatic 34-year-old man: a case report

Seth E Wakefield, Elliot L Dimberg, Steven A Moore, Brian S Tseng Journal of Medical Case Reports 2009, 3:8625 (24 July 2009)

Abstract | Full text | PDF | PubMed

57.

Research   Open Access Highly Accessed

Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance

David Martino, Yuk Jin Loke, Lavinia Gordon, Miina Ollikainen, Mark N Cruickshank, Richard Saffery, Jeffrey M Craig Genome Biology 2013, 14:R42 (22 May 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

A longitudinal study of DNA methylation in twins at birth and 18 months finds that some loci drift in methylation status

58.

Comment   Free Highly Accessed

Sequestration: inadvertently killing biomedical research to score political points

Jeffrey T Leek, Steven L Salzberg Genome Biology 2013, 14:109 (27 March 2013)

Abstract | Full text | PDF | PubMed | 1 comment |  Editor’s summary

Steven Salzberg and Jeff Leek are concerned about the Sequester's impact on biomedical research, and argue for a change in policy direction

59.

Comment   Free Highly Accessed

The passionate life of Simon Chan

Luca Comai Genome Biology 2013, 14:103 (30 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Luca Comai remembers the late Simon Chan, whose work on centromere evolution features in the current issue of Genome Biology

60.

Research article   Open Access Highly Accessed

Are behavioral interventions effective in increasing physical activity at 12 to 36 months in adults aged 55 to 70 years? a systematic review and meta-analysis

Nicola Hobbs, Alan Godfrey, Jose Lara, Linda Errington, Thomas D Meyer, Lynn Rochester, Martin White, John C Mathers, Falko F Sniehotta BMC Medicine 2013, 11:75 (19 March 2013)

Abstract | Full text | PDF | PubMed | 1 comment |  Editor’s summary

It is important to remain active in retirement to reduce the risk of age-related diseases; evidence from a systematic review and meta-analysis shows interventions improve physical activity in older adults, so could have significant health benefits.

61.

Research article   Open Access Highly Accessed

Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition

Sabine Rohrmann, Kim Overvad, H Bueno-de-Mesquita, Marianne U Jakobsen, Rikke Egeberg, Anne Tjønneland, Laura Nailler, Marie-Christine Boutron-Ruault, Françoise Clavel-Chapelon, Vittorio Krogh, Domenico Palli, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Manuela M Bergmann, Heiner Boeing, Kuanrong Li, Rudolf Kaaks, Kay-Tee Khaw, Nicholas J Wareham, Francesca L Crowe, Timothy J Key, Androniki Naska, Antonia Trichopoulou, Dimitirios Trichopoulos, Max Leenders, Petra HM Peeters, Dagrun Engeset, Christine L Parr, Guri Skeie et al. BMC Medicine 2013, 11:63 (7 March 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 2 comments |  Editor’s summary

A large study finds a positive association between processed meat consumption and mortality due to cardiovascular disease and cancer, indicating that reducing the amount of processed meat in the diet could reduce mortality risk.

62.

Research article   Open Access

Neuromuscular electrical stimulation for preventing skeletal-muscle weakness and wasting in critically ill patients: a systematic review

Nicola A Maffiuletti, Marc Roig, Eleftherios Karatzanos, Serafim Nanas BMC Medicine 2013, 11:137 (23 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Critically ill patients in intensive care are prone to muscle weakness and wasting; a systematic review suggests neuromuscular electrical stimulation therapy is effective in preventing muscle weakness, but is inconclusive for muscle wasting.

63.

Research article   Open Access Highly Accessed

Identifying bereaved subjects at risk of complicated grief: Predictive value of questionnaire items in a cohort study

Mai-Britt Guldin, Maja O'Connor, Ineta Sokolowski, Anders B Jensen, Peter Vedsted BMC Palliative Care 2011, 10:9 (16 May 2011)

Abstract | Full text | PDF | PubMed

64.

Research article   Open Access Highly Accessed

Managing change in the nursing handover from traditional to bedside handover – a case study from Mauritius

Hemant K Kassean, Zaheda B Jagoo BMC Nursing 2005, 4:1 (28 January 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

65.

Research article   Open Access Highly Accessed

A taxonomy of nursing care organization models in hospitals

Carl-Ardy Dubois, Danielle D’Amour, Eric Tchouaket, Michèle Rivard, Sean Clarke, Régis Blais BMC Health Services Research 2012, 12:286 (28 August 2012)

Abstract | Full text | PDF | PubMed

66.

Research article   Open Access Highly Accessed

Aggression and violence against health care workers in Germany - a cross sectional retrospective survey

Simone Franz, Annett Zeh, Anja Schablon, Saskia Kuhnert, Albert Nienhaus BMC Health Services Research 2010, 10:51 (25 February 2010)

Abstract | Full text | PDF | PubMed

67.

Research article   Open Access Highly Accessed

Barriers to the acceptance of electronic medical records by physicians from systematic review to taxonomy and interventions

Albert Boonstra, Manda Broekhuis BMC Health Services Research 2010, 10:231 (6 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

68.

Study protocol   Open Access

The CARTS study: Chemoradiation therapy for rectal cancer in the distal rectum followed by organ-sparing transanal endoscopic microsurgery

Guus MJ Bökkerink, Eelco JR de Graaf, Cornelis JA Punt, Iris D Nagtegaal, Heidi Rütten, Joost JME Nuyttens, Esther van Meerten, Pascal G Doornebosch, Pieter J Tanis, Eric J Derksen, Roy S Dwarkasing, Corrie AM Marijnen, Annemieke Cats, Rob AEM Tollenaar, Ignace HJT de Hingh, Harm JT Rutten, George P van der Schelling, Albert J ten Tije, Jeroen WA Leijtens, Guido Lammering, Geerard L Beets, Theo J Aufenacker, Apollo Pronk, Eric R Manusama, Christiaan Hoff, Andreas JA Bremers, Cornelelis Verhoef, Johannes HW de Wilt BMC Surgery 2011, 11:34 (15 December 2011)

Abstract | Full text | PDF | PubMed

69.

Research article   Open Access Highly Accessed

Comparison of the SF6D, the EQ5D, and the oswestry disability index in patients with chronic low back pain and degenerative disc disease

Lars G Johnsen, Christian Hellum, Øystein P Nygaard, Kjersti Storheim, Jens I Brox, Ivar Rossvoll, Gunnar Leivseth, Margreth Grotle BMC Musculoskeletal Disorders 2013, 14:148 (26 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

70.

Study protocol   Open Access Highly Accessed

Use of platelet rich plasma to treat plantar fasciitis: design of a multi centre randomized controlled trial

Joost C Peerbooms, Wilbert van Laar, Frank Faber, Hans M Schuller, Henk van der Hoeven, Taco Gosens BMC Musculoskeletal Disorders 2010, 11:69 (14 April 2010)

Abstract | Full text | PDF | PubMed

71.

Research article   Open Access

Increased expression of carbonic anhydrase I in the synovium of patients with ankylosing spondylitis

Xiaotian Chang, Jinxiang Han, Yan Zhao, Xinfeng Yan, Shui Sun, Yazhou Cui BMC Musculoskeletal Disorders 2010, 11:279 (8 December 2010)

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72.

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Divided by a lack of common language? - a qualitative study exploring the use of language by health professionals treating back pain

Karen L Barker, Margaret Reid, Catherine Lowe BMC Musculoskeletal Disorders 2009, 10:123 (5 October 2009)

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73.

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Effect of physical training on airway inflammation in bronchial asthma: a systematic review

Smita Pakhale, Vanessa Luks, Andrew Burkett, Lucy Turner BMC Pulmonary Medicine 2013, 13:38 (13 June 2013)

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74.

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Breast cancer knowledge, attitudes, and screening behaviors among African American women: the Black cosmetologists promoting health program

Georgia R Sadler, Celine M Ko, Jennifer A Cohn, Monique White, Rai-nesha Weldon, Phillis Wu BMC Public Health 2007, 7:57 (17 April 2007)

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75.

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Health-related quality of life in overweight German children and adolescents: do treatment-seeking youth have lower quality of life levels? Comparison of a clinical sample with the general population using a multilevel model approach

Emily Finne, Thomas Reinehr, Anke Schaefer, Katrin Winkel, Petra Kolip BMC Public Health 2013, 13:561 (8 June 2013)

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76.

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The fractionalization of physical activity throughout the week is associated with the cardiometabolic health of children and youth

Ian Janssen, Suzy L Wong, Rachel Colley, Mark S Tremblay BMC Public Health 2013, 13:554 (6 June 2013)

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Effectiveness of a facebook-delivered physical activity intervention for post-partum women: a randomized controlled trial protocol

Jocelyn Kernot, Tim Olds, Lucy K Lewis, Carol Maher BMC Public Health 2013, 13:518 (29 May 2013)

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78.

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‘All those things together made me retire’: qualitative study on early retirement among Dutch employees

Kerstin G Reeuwijk, Astrid de Wind, Marjan J Westerman, Jan Fekke Ybema, Allard J van der Beek, Goedele A Geuskens BMC Public Health 2013, 13:516 (28 May 2013)

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79.

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Gender differences in attitudes impeding colorectal cancer screening

Paul Ritvo, Ronald E Myers, Lawrence Paszat, Mardie Serenity, Daniel F Perez, Linda Rabeneck BMC Public Health 2013, 13:500 (24 May 2013)

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Acculturation and obesity among migrant populations in high income countries – a systematic review

Maryam Delavari, Anders Sønderlund, Boyd Swinburn, David Mellor, Andre Renzaho BMC Public Health 2013, 13:458 (10 May 2013)

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The role of nicotine replacement therapy for temporary abstinence in the home to protect children from environmental tobacco smoke exposure: a qualitative study with disadvantaged smokers

Olesya Atkinson, Tim Coleman, Ann McNeill, Sarah Lewis, Laura L Jones BMC Public Health 2013, 13:262 (22 March 2013)

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82.

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Process evaluation of a community-based adolescent obesity prevention project in Tonga

Kalesita F Fotu, Marj M Moodie, Helen M Mavoa, Siosifa Pomana, Jimaima T Schultz, Boyd A Swinburn BMC Public Health 2011, 11:284 (9 May 2011)

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83.

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A systematic review of evidence for the added benefits to health of exposure to natural environments

Diana E Bowler, Lisette M Buyung-Ali, Teri M Knight, Andrew S Pullin BMC Public Health 2010, 10:456 (4 August 2010)

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84.

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Definitions and factors associated with subthreshold depressive conditions: a systematic review

Mar Rodríguez, Roberto Nuevo, Somnath Chatterji, José Ayuso-Mateos BMC Psychiatry 2012, 12:181 (30 October 2012)

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Avoiding the 'twilight zone': recommendations for the transition of services from adolescence to adulthood for young people with ADHD

Susan Young, Clodagh M Murphy, David Coghill BMC Psychiatry 2011, 11:174 (3 November 2011)

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86.

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The alexithymic brain: the neural pathways linking alexithymia to physical disorders

Michiko Kano, Shin Fukudo BioPsychoSocial Medicine 2013, 7:1 (9 January 2013)

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87.

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AL Amyloidosis

Estelle Desport, Frank Bridoux, Christophe Sirac, Sébastien Delbes, Sébastien Bender, Béatrice Fernandez, Nathalie Quellard, Corinne Lacombe, Jean-Michel Goujon, David Lavergne, Julie Abraham, Guy Touchard, Jean-Paul Fermand, Arnaud Jaccard, Centre national de référence pour l’amylose AL et les autres maladies par dépôts d’immunoglobulines monoclonales Orphanet Journal of Rare Diseases 2012, 7:54 (21 August 2012)

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88.

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Isolates from hospital environments are the most virulent of the Candida parapsilosis complex

Raquel Sabino, Paula Sampaio, Catarina Carneiro, Laura Rosado, Célia Pais BMC Microbiology 2011, 11:180 (8 August 2011)

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89.

Short report   Open Access Highly Accessed

Development of a checklist to assess the quality of reporting of knowledge translation interventions using the Workgroup for Intervention Development and Evaluation Research (WIDER) recommendations

Lauren Albrecht, Mandy Archibald, Danielle Arseneau, Shannon D Scott Implementation Science 2013, 8:52 (16 May 2013)

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90.

Debate   Open Access Highly Accessed

A theory of organizational readiness for change

Bryan J Weiner Implementation Science 2009, 4:67 (19 October 2009)

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91.

Methodology   Open Access Highly Accessed

2011 SOSORT guidelines: Orthopaedic and Rehabilitation treatment of idiopathic scoliosis during growth

Stefano Negrini, Angelo G Aulisa, Lorenzo Aulisa, Alin B Circo, Jean de Mauroy, Jacek Durmala, Theodoros B Grivas, Patrick Knott, Tomasz Kotwicki, Toru Maruyama, Silvia Minozzi, Joseph P O'Brien, Dimitris Papadopoulos, Manuel Rigo, Charles H Rivard, Michele Romano, James H Wynne, Monica Villagrasa, Hans-Rudolf Weiss, Fabio Zaina Scoliosis 2012, 7:3 (20 January 2012)

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92.

Review   Open Access Highly Accessed

Adolescent idiopathic scoliosis: natural history and long term treatment effects

Marc A Asher, Douglas C Burton Scoliosis 2006, 1:2 (31 March 2006)

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93.

Research   Open Access

Intensity modulated radiotherapy in early stage Hodgkin lymphoma patients: Is it better than three dimensional conformal radiotherapy?

Vitaliana De Sanctis, Chiara Bolzan, Marco D’Arienzo, Stefano Bracci, Alessandro Fanelli, Maria Cox, Maurizio Valeriani, Mattia F Osti, Giuseppe Minniti, Laura Chiacchiararelli, Riccardo Enrici Radiation Oncology 2012, 7:129 (2 August 2012)

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94.

Debate   Open Access

Integrating a sense of coherence into the neonatal environment

Gill Thomson, Victoria Moran, Anna Axelin, Fiona Dykes, Renée Flacking BMC Pediatrics 2013, 13:84 (22 May 2013)

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95.

Study protocol   Open Access

The effectiveness of proactive telephone support provided to breastfeeding mothers of preterm infants: study protocol for a randomized controlled trial

Jenny Ericson, Mats Eriksson, Lena Hellström-Westas, Lars Hagberg, Pat Hoddinott, Renée Flacking BMC Pediatrics 2013, 13:73 (10 May 2013)

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96.

Research article   Open Access

Knowledge of risk factors, beliefs and practices of female healthcare professionals towards breast cancer in a tertiary institution in Lagos, Nigeria

Nasiru A Ibrahim, Olumuyiwa O Odusanya BMC Cancer 2009, 9:76 (4 March 2009)

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97.

Research article   Open Access

Reliability and validity of the ultrasound technique to measure the rectus femoris muscle diameter in older CAD-patients

Tom Thomaes, Martine Thomis, Steven Onkelinx, Walter Coudyzer, Véronique Cornelissen, Luc Vanhees BMC Medical Imaging 2012, 12:7 (2 April 2012)

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98.

Study protocol   Open Access Highly Accessed

A New Model of Delirium Care in the Acute Geriatric Setting: Geriatric Monitoring Unit

Mei Chong, Mark PC Chan, Jasmine Kang, Huey Han, Yew Ding, Thai Tan BMC Geriatrics 2011, 11:41 (13 August 2011)

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99.

Research article   Open Access

Nationwide continuous monitoring of end-of-life care via representative networks of general practitioners in Europe

Lieve Van den Block, Bregje Onwuteaka-Philipsen, Koen Meeussen, Gé Donker, Francesco Giusti, Guido Miccinesi, Viviane Van Casteren, Tomas Vega Alonso, Oscar Zurriaga, Luc Deliens BMC Family Practice 2013, 14:73 (3 June 2013)

Abstract | Provisional PDF | PubMed

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