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76.

Review   Open Access Highly Accessed

Joubert Syndrome and related disorders

Francesco Brancati, Bruno Dallapiccola, Enza Valente Orphanet Journal of Rare Diseases 2010, 5:20 (8 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

77.

Review   Open Access Highly Accessed

Toxic epidermal necrolysis and Stevens-Johnson syndrome

Thomas Harr, Lars E French Orphanet Journal of Rare Diseases 2010, 5:39 (16 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

78.

Research article   Open Access Highly Accessed

Giant viruses coexisted with the cellular ancestors and represent a distinct supergroup along with superkingdoms Archaea, Bacteria and Eukarya

Arshan Nasir, Kyung Kim, Gustavo Caetano-Anolles BMC Evolutionary Biology 2012, 12:156 (24 August 2012)

Abstract | Full text | PDF | PubMed | 1 comment

79.

Research   Open Access Highly Accessed

Changing perceptions of hunger on a high nutrient density diet

Joel Fuhrman, Barbara Sarter, Dale Glaser, Steve Acocella Nutrition Journal 2010, 9:51 (7 November 2010)

Abstract | Full text | PDF | PubMed

80.

Review   Open Access Highly Accessed

Food Advertising and Marketing Directed at Children and Adolescents in the US

Mary Story, Simone French International Journal of Behavioral Nutrition and Physical Activity 2004, 1:3 (10 February 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

81.

Study protocol   Open Access Highly Accessed

Collaborative Care for Older Adults with low back pain by family medicine physicians and doctors of chiropractic (COCOA): study protocol for a randomized controlled trial

Christine M Goertz, Stacie A Salsbury, Robert D Vining, Cynthia R Long, Andrew A Andresen, Mark E Jones, Kevin J Lyons, Maria A Hondras, Lisa Z Killinger, Fredric D Wolinsky, Robert B Wallace Trials 2013, 14:18 (16 January 2013)

Abstract | Full text | PDF | PubMed

82.

Review   Open Access Highly Accessed

Osteopetrosis

Zornitza Stark, Ravi Savarirayan Orphanet Journal of Rare Diseases 2009, 4:5 (20 February 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

83.

Case report   Open Access Highly Accessed

Mitochondrial myopathy presenting as fibromyalgia: a case report

Mishal Abdullah, Sahana Vishwanath, Amro Elbalkhi, Julian L Ambrus Journal of Medical Case Reports 2012, 6:55 (10 February 2012)

Abstract | Full text | PDF | PubMed

84.

Research article   Open Access Highly Accessed

High degree of efficacy in the treatment of cyclic vomiting syndrome with combined co-enzyme Q10, L-carnitine and amitriptyline, a case series

Richard G Boles BMC Neurology 2011, 11:102 (16 August 2011)

Abstract | Full text | PDF | PubMed

85.

Debate   Open Access

Pragmatic controlled clinical trials in primary care: the struggle between external and internal validity

Marshall Godwin, Lucia Ruhland, Ian Casson, Susan MacDonald, Dianne Delva, Richard Birtwhistle, Miu Lam, Rachelle Seguin BMC Medical Research Methodology 2003, 3:28 (22 December 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

86.

Research article   Open Access Highly Accessed

Methods for the thematic synthesis of qualitative research in systematic reviews

James Thomas, Angela Harden BMC Medical Research Methodology 2008, 8:45 (10 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

87.

Commentary   Open Access Highly Accessed

The case study approach

Sarah Crowe, Kathrin Cresswell, Ann Robertson, Guro Huby, Anthony Avery, Aziz Sheikh BMC Medical Research Methodology 2011, 11:100 (27 June 2011)

Abstract | Full text | PDF | PubMed

88.

Review   Open Access Highly Accessed

Critical care management of severe traumatic brain injury in adults

Samir H Haddad, Yaseen M Arabi Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012, 20:12 (3 February 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

89.

Review   Open Access Highly Accessed

Acne vulgaris, probiotics and the gut-brain-skin axis - back to the future?

Whitney P Bowe, Alan C Logan Gut Pathogens 2011, 3:1 (31 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

90.

Review   Open Access Highly Accessed

Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options

Gerhard J Molderings, Stefan Brettner, Jürgen Homann, Lawrence B Afrin Journal of Hematology & Oncology 2011, 4:10 (22 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

91.

Research article   Open Access Highly Accessed

Plant growth strategies are remodeled by spaceflight

Anna-Lisa Paul, Claire E Amalfitano, Robert J Ferl BMC Plant Biology 2012, 12:232 (7 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Arabidopsis plants grown in the absence of gravity exhibit the same root growth morphology as controls grown on earth, indicating that their characteristic skewing and waving patterns are a gravity independent phenomenon.

92.

Review   Open Access Highly Accessed

International Society of Sports Nutrition position stand: energy drinks

Bill Campbell, Colin Wilborn, Paul La Bounty, Lem Taylor, Mike T Nelson, Mike Greenwood, Tim N Ziegenfuss, Hector L Lopez, Jay R Hoffman, Jeffrey R Stout, Stephen Schmitz, Rick Collins, Doug S Kalman, Jose Antonio, Richard B Kreider Journal of the International Society of Sports Nutrition 2013, 10:1 (3 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A systematic review on energy drinks, from the International Society of Sports Nutrition.

93.

Comment   Free Highly Accessed

Sequestration: inadvertently killing biomedical research to score political points

Jeffrey T Leek, Steven L Salzberg Genome Biology 2013, 14:109 (27 March 2013)

Abstract | Full text | PDF | PubMed | 1 comment |  Editor’s summary

Steven Salzberg and Jeff Leek are concerned about the Sequester's impact on biomedical research, and argue for a change in policy direction

94.

Research article   Open Access Highly Accessed

Depression, antidepressant medications, and risk of Clostridium difficile infection

Mary A M Rogers, M Todd Greene, Vincent B Young, Sanjay Saint, Kenneth M Langa, John Y Kao, David M Aronoff BMC Medicine 2013, 11:121 (7 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The risk of Clostridium difficile infection is increased in adults with depression and in those taking antidepressants during hospitalization, indicating that physicians should be aware of the elevated infection risk in these patients.

95.

Research article   Open Access Highly Accessed

Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity

Anna Sapone, Karen M Lammers, Vincenzo Casolaro, Marcella Cammarota, Maria Giuliano, Mario De Rosa, Rosita Stefanile, Giuseppe Mazzarella, Carlo Tolone, Maria Russo, Pasquale Esposito, Franca Ferraraccio, Maria Cartenì, Gabriele Riegler, Laura de Magistris, Alessio Fasano BMC Medicine 2011, 9:23 (9 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Celiac disease and gluten sensitivity sufferers have similar pathologies triggered by gluten ingestion, but have different mucosal immune profiles and gut permeabilities, which may explain the less severe pathology of gluten sensitivity as compared to celiac disease.

96.

Research article   Open Access Highly Accessed

Effectiveness of Compounded Bioidentical Hormone Replacement Therapy: An Observational Cohort Study

Andres D Ruiz, Kelly R Daniels, Jamie C Barner, John J Carson, Christopher R Frei BMC Women's Health 2011, 11:27 (8 June 2011)

Abstract | Full text | PDF | PubMed

97.

Research article   Open Access Highly Accessed

Identification of nursing assessment models/tools validated in clinical practice for use with diverse ethno-cultural groups: an integrative review of the literature

Gina MA Higginbottom, Magdalena S Richter, Ramadimetja S Mogale, Lucenia Ortiz, Susan Young, Obianuju Mollel BMC Nursing 2011, 10:16 (3 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

98.

Research article   Open Access Highly Accessed

Barriers to the acceptance of electronic medical records by physicians from systematic review to taxonomy and interventions

Albert Boonstra, Manda Broekhuis BMC Health Services Research 2010, 10:231 (6 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

99.

Research article   Open Access Highly Accessed

Group based diabetes self-management education compared to routine treatment for people with type 2 diabetes mellitus. A systematic review with meta-analysis

Aslak Steinsbekk, LisbethØ Rygg, Monde Lisulo, Marit B Rise, Atle Fretheim BMC Health Services Research 2012, 12:213 (23 July 2012)

Abstract | Full text | PDF | PubMed

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