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Rapid production of antigen-specific monoclonal antibodies from a variety of animals
Nobuyuki Kurosawa, Megumi Yoshioka, Rika Fujimoto, Fuminori Yamagishi, Masaharu Isobe BMC Biology 2012, 10:80 (28 September 2012)
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Editor’s summary
Using a fluorescent dye to label the greatly expanded endoplasmic reticulum characteristic of antibody-secreting cells, Kurosawa and colleagues demonstrate how monoclonal antibodies can be produced from a variety of immunized animals in just one week.
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Recent advances in asthma genetics
Jian Zhang, Peter D Paré, Andrew J Sandford Respiratory Research 2008, 9:4 (15 January 2008)
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| PubMed | Cited on BioMed Central
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Development and application of an antigen capture ELISA assay for diagnosis of Japanese encephalitis virus in swine, human and mosquito
Li Mei, Peng Wu, Jing Ye, Guangping Gao, Lin Shao, Shaomei Huang, Yaoming Li, Xiaohong Yang, Huanchun Chen, Shengbo Cao Virology Journal 2012, 9:4 (6 January 2012)
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Childhood obesity, prevalence and prevention
Mahshid Dehghan, Noori Akhtar-Danesh, Anwar T Merchant Nutrition Journal 2005, 4:24 (2 September 2005)
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| PubMed | Cited on BioMed Central |
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Effector granules in human T lymphocytes: the luminal proteome of secretory lysosomes from human T cells
Hendrik Schmidt, Christoph Gelhaus, Melanie Nebendahl, Marcus Lettau, Ralph Lucius, Matthias Leippe, Dietrich Kabelitz, Ottmar Janssen Cell Communication and Signaling 2011, 9:4 (21 January 2011)
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| PubMed | Cited on BioMed Central
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6.
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The effect of earplugs during the night on the onset of delirium and sleep perception: a randomized controlled trial in intensive care patients
Bart Van Rompaey, Monique M Elseviers, Wim Van Drom, Veronique Fromont, Philippe G Jorens Critical Care 2012, 16:R73 (4 May 2012)
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| PubMed | Cited on BioMed Central |
| F1000 Biology
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Editor’s summary
The use of earplugs in the ICU can lead to a better night's sleep for patients, lower the incidence of confusion, and delay the onset of cognitive disturbances.
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7.
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Stool substitute transplant therapy for the eradication of Clostridium difficile infection: ‘RePOOPulating’ the gut
Elaine O Petrof, Gregory B Gloor, Stephen J Vanner, Scott J Weese, David Carter, Michelle C Daigneault, Eric M Brown, Kathleen Schroeter, Emma Allen-Vercoe Microbiome 2013, 1:3 (9 January 2013)
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Editor’s summary
A super-probiotic synthetic stool, composed of 33 different bacterial strains, was developed and used to treat two patients with severe C. difficile infection. The probiotic bacteria could still be detected up to six months after inoculation.
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8.
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Q&A: 'Toxic' effects of sugar: should we be afraid of fructose?
Luc Tappy BMC Biology 2012, 10:42 (21 May 2012)
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Editor’s summary
Before the colonial era of sugar plantations we consumed, on average, about 15-fold less fructose than we do today. Luc Tappy explains, in question and answer format, the special features of fructose metabolism and discusses the evidence that high fructose intake has contributed to the current epidemic of obesity and metabolic disease.
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Spectrum of gluten-related disorders: consensus on new nomenclature and classification
Anna Sapone, Julio C Bai, Carolina Ciacci, Jernej Dolinsek, Peter HR Green, Marios Hadjivassiliou, Katri Kaukinen, Kamran Rostami, David S Sanders, Michael Schumann, Reiner Ullrich, Danilo Villalta, Umberto Volta, Carlo Catassi, Alessio Fasano BMC Medicine 2012, 10:13 (7 February 2012)
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| PubMed
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Editor’s summary
Fasano and colleagues propose new nomenclature and classifications within the spectrum of gluten-related disorders (GRDs), prompted by indications from the past decade that reactions to gluten may be caused by conditions other than celiac disease.
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10.
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Cancer dynamics for identical twin brothers
Ali Ghaffari, Mostafa Khazaee Theoretical Biology and Medical Modelling 2012, 9:4 (6 February 2012)
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| PubMed
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11.
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The weight of nations: an estimation of adult human biomass
Sarah Walpole, David Prieto-Merino, Phil Edwards, John Cleland, Gretchen Stevens, Ian Roberts BMC Public Health 2012, 12:439 (18 June 2012)
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Editor’s summary
National food energy requirements are primarily determined by the total biomass of the population rather than the population, suggesting that increasing body mass could have the same implications for world energy requirements as an extra 473 million people on earth.
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12.
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Understanding the benefit of metformin use in cancer treatment
Ryan JO Dowling, Pamela J Goodwin, Vuk Stambolic BMC Medicine 2011, 9:33 (6 April 2011)
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Editor’s summary
Metformin has long been known to combat diabetes, but its mechanisms of action are now known to also provide potent anti-tumor action, reviewed here by Stambolic and colleagues.
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13.
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A qualitative study of nursing student experiences of clinical practice
Farkhondeh Sharif, Sara Masoumi BMC Nursing 2005, 4:6 (9 November 2005)
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| PubMed
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14.
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Physical education, school physical activity, school sports and academic performance
François Trudeau, Roy J Shephard International Journal of Behavioral Nutrition and Physical Activity 2008, 5:10 (25 February 2008)
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| PubMed | Cited on BioMed Central
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15.
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ISSN exercise & sport nutrition review: research & recommendations
Richard B Kreider, Colin D Wilborn, Lem Taylor, Bill Campbell, Anthony L Almada, Rick Collins, Mathew Cooke, Conrad P Earnest, Mike Greenwood, Douglas S Kalman, Chad M Kerksick, Susan M Kleiner, Brian Leutholtz, Hector Lopez, Lonnie M Lowery, Ron Mendel, Abbie Smith, Marie Spano, Robert Wildman, Darryn S Willoughby, Tim N Ziegenfuss, Jose Antonio Journal of the International Society of Sports Nutrition 2010, 7:7 (2 February 2010)
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| PubMed | Cited on BioMed Central
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16.
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Nutritional therapies for mental disorders
Shaheen E Lakhan, Karen F Vieira Nutrition Journal 2008, 7:2 (21 January 2008)
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17.
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Weight Science: Evaluating the Evidence for a Paradigm Shift
Linda Bacon, Lucy Aphramor Nutrition Journal 2011, 10:9 (24 January 2011)
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| PubMed | Cited on BioMed Central
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18.
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The effects of oral iron supplementation on cognition in older children and adults: a systematic review and meta-analysis
Martin Falkingham, Asmaa Abdelhamid, Peter Curtis, Susan Fairweather-Tait, Louise Dye, Lee Hooper Nutrition Journal 2010, 9:4 (25 January 2010)
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19.
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Language acquisition for deaf children: Reducing the harms of zero tolerance to the use of alternative approaches
Tom Humphries, Poorna Kushalnagar, Gaurav Mathur, Donna Napoli, Carol Padden, Christian Rathmann, Scott R Smith Harm Reduction Journal 2012, 9:16 (2 April 2012)
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20.
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A stable pattern of EEG spectral coherence distinguishes children with autism from neuro-typical controls - a large case control study
Frank H Duffy, Heidelise Als BMC Medicine 2012, 10:64 (26 June 2012)
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Editor’s summary
A large scale study assessing electroencephalography (EEG) patterns in children diagnosed with autism and matched controls identifies differences between these groups, which could be used to provide an EEG signature for autism diagnosis.
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21.
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Managing change in the nursing handover from traditional to bedside handover – a case study from Mauritius
Hemant K Kassean, Zaheda B Jagoo BMC Nursing 2005, 4:1 (28 January 2005)
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| PubMed | Cited on BioMed Central
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22.
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A macroepigenetic approach to identify factors responsible for the autism epidemic in the United States
Renee Dufault, Walter J Lukiw, Raquel Crider, Roseanne Schnoll, David Wallinga, Richard Deth Clinical Epigenetics 2012, 4:6 (10 April 2012)
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23.
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An observational study of associations among maternal fluids during parturition, neonatal output, and breastfed newborn weight loss
Joy Noel-Weiss, A Kirsten Woodend, Wendy E Peterson, William Gibb, Dianne L Groll International Breastfeeding Journal 2011, 6:9 (15 August 2011)
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| PubMed | Cited on BioMed Central
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Editor’s summary
The volume of intravenous fluids received by women during labour impacts newborn birth weight, meaning weight loss in the first 24 hours post delivery may not be a true measure of early breastfeeding success.
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24.
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Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells
Yong Zhao, Zhaoshun Jiang, Tingbao Zhao, Mingliang Ye, Chengjin Hu, Zhaohui Yin, Heng Li, Ye Zhang, Yalin Diao, Yunxiang Li, Yingjian Chen, Xiaoming Sun, Mary Fisk, Randal Skidgel, Mark Holterman, Bellur Prabhakar, Theodore Mazzone BMC Medicine 2012, 10:3 (10 January 2012)
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Editor’s summary
The safe reversal of Type 1 diabetes is possible with Stem Cell Educator therapy which uses stem cells from cord blood to re-educate a diabetic's own T cells, restarts pancreatic function, and reduces the need for insulin.
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25.
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Perinatal nicotine exposure induces asthma in second generation offspring
Virender K Rehan, Jie Liu, Erum Naeem, Jia Tian, Reiko Sakurai, Kenny Kwong, Omid Akbari, John S Torday BMC Medicine 2012, 10:129 (30 October 2012)
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| PubMed | Cited on BioMed Central
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Editor’s summary
Smoking during pregnancy induces asthma in offspring, and the effects are permanently transmitted to subsequent generations via epigenetic changes in germ cells, providing a breakthrough in studying transgenerational effects of toxins.
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