ColorCode 3-D (Maged Nabih Kamel Boulos, 06Nov2009)
Another anaglyph-like system worth mentioning that promises good colour fidelity: http://www.colorcode3d.com/info/pages/what_is_cc3d.pdf... read full comment

Correction to this article (Akira Kato, 06Nov2009)
In the legend to Figure 1, scale bars represent "100 mm" instead of "50 mm".... read full comment

Routine use of weaning preditors: better if we go faster (Sergio Nemer, 06Nov2009)
Srgio N. Nemer and Carmen S.V. Barbas We thank Dr. Epstein for his interest in our article. We also thank him for his interesting comments and considerations. We agree that the great majority of weaning predictors presented only moderate accuracy in predicting the weaning outcome. Although, some integrative indexes, like the frequency to tidal volume ratio (f / Vt ratio) [1] and the ratio of airway occlusion pressure to maximal inspiratory... read full comment

Note from the author (Sean Rice, 05Nov2009)
This is the first in a series of papers deriving the exact mathematical rules underlying evolution. A description of the project, and links to other papers in the series is found at:<http://bi154.dhcp.ttu.edu/axiomatic/>.... read full comment

addendum to article (Henrik Edgren, 05Nov2009)
Information on the exact nonsense mutation in RIC8A was inadvertently omitted from the article. The mutation is c724G>T resulting in pGlu242X in the protein sequence. We regret this oversight.... read full comment

Outcome misclassification and incorrect odds ratios (Aaron Kipp, 05Nov2009)
In the ongoing struggle against TB transmission and drug resistant TB, information on treatment outcomes and what factors affect these outcomes are vitally important. Tessema et al take the first step toward that goal by reporting for the first time on treatment outcomes in northwest Ethiopia since the introduction of directly observed therapy in 2000 at the Gondar University Teaching Hospital. However, I believe there are some serious limitations... read full comment

UNCLEAR ARTICLE (Vikal Shakya, 05Nov2009)
The cause of the conversion has not been mentioned anywhere in the case report. Neither do we have nay photographs that can give us an idea of the type of the bile dust injury (assumed from the discussion section). The spelling of cholecystectomy in the title is also incorrect. ... read full comment

Query about materials (Shaun Fountain, 05Nov2009)
Great series very useful for patient information. It would be reassuring to know that the two deaths reported were not related to the tape procedure.... read full comment

Why are we only given information on 3 out of the 8 SF-36 subscales? (Tom Kindlon, 05Nov2009)
Reading this paper, one could be forgiven for thinking that the SF-36 questionnaire only has 3 subscales: Physical Functioning, Mental Health and Social Functioning as that is all we are given information on. In fact, of course, the SF-36 questionnaire has 8 subscales: Physical function, Role physical, Bodily pain, General health, Vitality, Social function, Role emotional and Mental health[1]. The authors use the empiric definition for CFS[2]... read full comment

There has been criticism of how CFS is defined in this study (Tom Kindlon, 05Nov2009)
I thought it would be useful to point out that there is controversy [1,2] with regard to the criteria [3] used in this study to define Chronic Fatigue Syndrome (CFS). For example, the criteria for CFS used in this study do not even require a patient to have fatigue. The authors say: We used the Multidimensional Fatigue Inventory (MFI-20) [4] to measure characteristics of fatigue but they do not give the thresholds. Given the MFI-20 has five... read full comment

A more detailed comparison would need to be made before one could say this replicates the previous study (Tom Kindlon, 05Nov2009)
Part of the aim of this study [1] appears to be to compare the classes that were drawn up with a previous cohort[2-4]. However it does not, to my mind, deal with this in a particularly rigorous fashion. The main quantitative comparisons are the percentages that fall in each class (Tables 6 and 7). However, the percentages will be influence by the quantity and type of non-CFS controls used which are not the same in each cohort [to explain... read full comment

Further information (I Martin Sheldon, 01Nov2009)
Further information on host-pathogen interactions in the endometrium are to be found at our website: www.crib.swansea.ac.uk Martin Sheldon... read full comment

Authors' response to reader comment (Jolayne Houtz, 30Oct2009)
We appreciate the attention to this detail by Dr Cheng. The point raised is correct and was indeed due to a skip pattern in the NHANES questionnaire. We repeated the analysis to evaluate the influence on the coefficients of regression within NHANES and predicted diabetes prevalence. Three coefficients (smoking, age 60-69, and age 70+) changed by less than 10%, and the rest remained unchanged. Predicted diabetes prevalence for different state-sex-age-race-insurance... read full comment

Comments on the missing values of smoking and insurance status (Yiling Cheng, 29Oct2009)
This article demonstrated a simple and innovative approach to answer an important question that is what the total diabetes prevalences by US states are. I read it with great interesting and noticed the authors mentioned that there were 50.2% of observations in NHANES were missing either smoking or insurance status According to the documentations, this is extremely too high. For example, in NHANES 2003-2004, persons aged 20 years or older had one... read full comment

Link is dead (Joachim EM Jacob, 29Oct2009)
Just to point out that the link in the abstract is dead.... read full comment

GIST with spontaneous raputure (Tomoaki Ando, 29Oct2009)
We consider that a case of gastrointestinal stromal tumor with spontaneous rupture in the greater omentum is rare and educational. ... read full comment

Reduction of late stillbirth - reply from the authors (Frederik Fren, 29Oct2009)
Dear Sir, Salvesens comment to our study has just come to our attention, and we appreciate the opportunity to clarify. The comments have questions regarding three aspects of our study: 1. How come the effect is not reflected in publicly available data? 2. How come mortality seems lower already in the first month of intervention? 3. How come the intervention seems to lower mortality without increasing maternal concern and/or interventions? 1) To... read full comment

The Authors Respond: Results of the Study are Positive (Daniel Rossignol, 26Oct2009)
We again thank Drs. Mintz, Mink, and Wiznitzer for their comments on our article reporting our double-blind controlled study demonstrating the effectiveness of hyperbaric treatment in children with autism. We address their additional concerns as follows: 1. Since the CGI-I is a scale of improvement, the only scores obtained for the physician CGI-I scale were generated at the end of the study. To obtain these scores, the physician rated the childs... read full comment

Correction from The Authors (Damion Nero, 26Oct2009)
The authors of this work wish to note two corrections to the reference section of our manuscript. Corrections Citation 25: A. Tanay, R. Sharan, R. Shamir. Discovering Statistically Significant Biclusters in Gene Expression Data. Bioinformatics 2002, Vol. 18 Suppl. 1 S136-S144. Citation 31: R. Sharan, A. Maron-Katz and R. Shamir. CLICK and EXPANDER: A System for Clustering and Visualizing Gene Expression Data. Bioinformatics, Vol. 19, No. 14,... read full comment

Typo/grammar (Marc Eppley, 26Oct2009)
The final sentence of the paragraph following Table 2 beginning "We further investigated..." contains a grammatical error or typo. I'm not sure exactly what was intended. "This suggests that the mutations in A/H1N1 that predispose for the human interaction pattern are remarkable of more prevalent than mutations that predispose for the swine interaction pattern."... read full comment