1.
The impact of socio-economic status on health related quality of life for children and adolescents with heart disease
Amy
Cassedy,
Dennis
Drotar,
Richard
Ittenbach,
Shawna
Hottinger,
Jo
Wray,
Gil
Wernovsky,
Jane
W
Newburger,
Lynn
Mahony,
Kathleen
Mussatto,
Mitchell
I
Cohen,
Bradley
S
Marino
Health and Quality of Life Outcomes 2013, 11 :99 (18 June 2013)
Abstract | Provisional PDF
2.
Proton channel HVCN1 is required for effector functions of mouse eosinophils
Xiang
Zhu,
Eucabeth
Mose,
Nives
Zimmermann
BMC Immunology 2013, 14 :24 (24 May 2013)
Abstract | Full text | PDF | PubMed
3.
Epidemiological analysis of respiratory viral etiology for influenza-like illness during 2010 in Zhuhai, China
Hongxia
Li,
Quande
Wei,
Aijun
Tan,
Leyi
Wang
Virology Journal 2013, 10 :143 (7 May 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
A study of respiratory disease in Zhuhai, China, found seasonal patterns of influenza virus, respiratory syncytial virus, and human metapneumovirus as well as correlations between some viruses with air temperature or air humidity.
4.
Mining FDA drug labels for medical conditions
Qi
Li,
Louise
Deleger,
Todd
Lingren,
Haijun
Zhai,
Megan
Kaiser,
Laura
Stoutenborough,
Anil
G
Jegga,
Kevin Bretonnel
Cohen,
Imre
Solti
BMC Medical Informatics and Decision Making 2013, 13 :53 (24 April 2013)
Abstract | Full text | PDF | PubMed
5.
Evaluation of propofol anesthesia in morbidly obese children and adolescents
Vidya
Chidambaran,
Senthilkumar
Sadhasivam,
Jeroen
Diepstraten,
Hope
Esslinger,
Shareen
Cox,
Beverly
M
Schnell,
Paul
Samuels,
Thomas
Inge,
Alexander
A
Vinks,
Catherijne
A
Knibbe
BMC Anesthesiology 2013, 13 :8 (21 April 2013)
Abstract | Full text | PDF | PubMed
6.
Early microbial and metabolomic signatures predict later onset of necrotizing enterocolitis in preterm infants
Ardythe
L
Morrow,
Anne
J
Lagomarcino,
Kurt
R
Schibler,
Diana
H
Taft,
Zhuoteng
Yu,
Bo
Wang,
Mekibib
Altaye,
Michael
Wagner,
Dirk
Gevers,
Doyle
V
Ward,
Michael
A
Kennedy,
Curtis
Huttenhower,
David
S
Newburg
Microbiome 2013, 1 :13 (16 April 2013)
Abstract | Full text | PDF
|
Editor’s summary
Abnormal gut bacteria in premature babies was found days before the onset of necrotizing enterocolitis and could also be determined indirectly from urine, providing a possible biomarker for disease.
7.
Functional neuronal network activity differs with cognitive dysfunction in childhood-onset systemic lupus erythematosus
Mark
W
DiFrancesco,
Darren
R
Gitelman,
Marisa
S
Klein-Gitelman,
Anna Carmela
P
Sagcal-Gironella,
Frank
Zelko,
Dean
Beebe,
Todd
Parrish,
Jessica
Hummel,
Jun
Ying,
Hermine
I
Brunner
Arthritis Research & Therapy 2013, 15 :R40 (7 March 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Functional MRI (fMRI) detection of differential neuronal network activation could be a candidate imaging biomarker for neurocognitive dysfunction (NCD) in childhood-onset systemic lupus erythematosus.
8.
Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury
Stephan
W
Glasser,
Albert
P
Senft,
Melissa
D
Maxfield,
Teah
L
Ruetschilling,
John
E
Baatz,
Kristen
Page,
Thomas
R
Korfhagen
Respiratory Research 2013, 14 :19 (12 February 2013)
Abstract | Full text | PDF | PubMed
9.
TGFβ signaling regulates lipogenesis in human sebaceous glands cells
Adrian
J
McNairn,
Yanne
Doucet,
Julien
Demaude,
Marion
Brusadelli,
Christopher
B
Gordon,
Armando
Uribe-Rivera,
Paul
F
Lambert,
Charbel
Bouez,
Lionel
Breton,
Géraldine
Guasch
BMC Dermatology 2013, 13 :2 (23 January 2013)
Abstract | Full text | PDF | PubMed
10.
A study of two Chinese patients with tetrasomy and pentasomy 15q11q13 including Prader-Willi/Angelman syndrome critical region present with developmental delays and mental impairment
Jing
Yang,
Yongchen
Yang,
Yi
Huang,
Yan
Hu,
Xi
Chen,
Hengjuan
Sun,
Zhibao
Lv,
Qian
Cheng,
Liming
Bao
BMC Medical Genetics 2013, 14 :9 (15 January 2013)
Abstract | Full text | PDF | PubMed
11.
Novel variations in the adiponectin gene (ADIPOQ ) may affect distribution of oligomeric complexes
Leah
C
Kottyan,
Jessica
G
Woo,
Mehdi
Keddache,
Walter
Banach,
Nancy
A
Crimmins,
Lawrence
M
Dolan,
Lisa
J
Martin
SpringerPlus 2012, 1 :66 (14 December 2012)
Abstract | Full text | PDF
12.
Childhood immunization rates in rural Intibucá, Honduras: an analysis of a local database tool and community health center records for assessing and improving vaccine coverage
Yuan
He,
Alan
Zarychta,
Joseph
B
Ranz,
Mary
Carroll,
Lori
M
Singleton,
Paria
M
Wilson,
Elizabeth
P
Schlaudecker
BMC Public Health 2012, 12 :1056 (7 December 2012)
Abstract | Full text | PDF | PubMed
13.
Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children
Hector
R
Wong,
Natalie
Z
Cvijanovich,
Mark
Hall,
Geoffrey
L
Allen,
Neal
J
Thomas,
Robert
J
Freishtat,
Nick
Anas,
Keith
Meyer,
Paul
A
Checchia,
Richard
Lin,
Michael
T
Bigham,
Anita
Sen,
Jeffrey
Nowak,
Michael
Quasney,
Jared
W
Henricksen,
Arun
Chopra,
Sharon
Banschbach,
Eileen
Beckman,
Kelli
Harmon,
Patrick
Lahni,
Thomas
P
Shanley
Critical Care 2012, 16 :R213 (29 October 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
14.
Quantitative myocardial perfusion in mice based on the signal intensity of flow sensitized CMR
Sumeda
Abeykoon,
Michelle
Sargent,
Janaka
P
Wansapura
Journal of Cardiovascular Magnetic Resonance 2012, 14 :73 (24 October 2012)
Abstract | Full text | PDF | PubMed
15.
The pediatric sepsis biomarker risk model
Hector
R
Wong,
Shelia
Salisbury,
Qiang
Xiao,
Natalie
Z
Cvijanovich,
Mark
Hall,
Geoffrey
L
Allen,
Neal
J
Thomas,
Robert
J
Freishtat,
Nick
Anas,
Keith
Meyer,
Paul
A
Checchia,
Richard
Lin,
Thomas
P
Shanley,
Michael
T
Bigham,
Anita
Sen,
Jeffrey
Nowak,
Michael
Quasney,
Jared
W
Henricksen,
Arun
Chopra,
Sharon
Banschbach,
Eileen
Beckman,
Kelli
Harmon,
Patrick
Lahni,
Christopher
J
Lindsell
Critical Care 2012, 16 :R174 (1 October 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
A biomarker-based risk model to stratify pediatric septic shock outcomes reliably identifies children at risk of death and has potential applications for clinical trial stratification, patient decision-making, and quality assurance.
16.
Prolonged FGF signaling is necessary for lung and liver induction in Xenopus
Emily
T
Shifley,
Alan
P
Kenny,
Scott
A
Rankin,
Aaron
M
Zorn
BMC Developmental Biology 2012, 12 :27 (18 September 2012)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Fibroblast Growth Factor (FGF) signaling from the mesoderm is required to induce liver and lung development in Xenopus with the duration of this signal, rather than the strength, important for full differentiation of these organs
17.
The role of protease-activated receptor-2 on pulmonary neutrophils in the innate immune response to cockroach allergen
Riad
Lutfi,
Ian
P
Lewkowich,
Ping
Zhou,
John
R
Ledford,
Kristen
Page
Journal of Inflammation 2012, 9 :32 (6 September 2012)
Abstract | Full text | PDF | PubMed
18.
Food group intake patterns and nutrient intake vary across low-income Hispanic and African American preschool children in Atlanta: a cross sectional study
Deborah
Salvo,
Jennifer
K
Frediani,
Thomas
R
Ziegler,
Conrad
R
Cole
Nutrition Journal 2012, 11 :62 (29 August 2012)
Abstract | Full text | PDF | PubMed
19.
Algorithm development for corticosteroid management in systemic juvenile idiopathic arthritis trial using consensus methodology
Norman
T
Ilowite,
Christy
I
Sandborg,
Brian
M
Feldman,
Alexi
Grom,
Laura
E
Schanberg,
Edward
H
Giannini,
Carol
A
Wallace,
Rayfel
Schneider,
Kathleen
Kenney,
Beth
Gottlieb,
Philip
J
Hashkes,
Lisa
Imundo,
Yukiko
Kimura,
Bianca
Lang,
Michael
Miller,
Diana
Milojevic,
Kathleen
M
O’Neil,
Marilynn
Punaro,
Natasha
Ruth,
Nora
G
Singer,
Richard
K
Vehe,
James
Verbsky,
Amy
Woodward,
Lawrence
Zemel
Pediatric Rheumatology 2012, 10 :31 (29 August 2012)
Abstract | Full text | PDF | PubMed
20.
Quantitative criteria for improving performance of buccal DNA for high-throughput genetic analysis
Jessica
G
Woo,
Lisa
J
Martin,
Lili
Ding,
W
Brown,
Timothy
D
Howard,
Carl
D
Langefeld,
Charles
J
Moomaw,
Mary
Haverbusch,
Guangyun
Sun,
Subba
R
Indugula,
Hong
Cheng,
Ranjan
Deka,
Daniel
Woo
BMC Genetics 2012, 13 :75 (25 August 2012)
Abstract | Full text | PDF | PubMed
21.
Low-level HIV infection of hepatocytes
Ling
Kong,
Walter
Maya,
Maria
E
Moreno-Fernandez,
Gang
Ma,
Mohamed
T
Shata,
Kenneth
E
Sherman,
Claire
Chougnet,
Jason
T
Blackard
Virology Journal 2012, 9 :157 (9 August 2012)
Abstract | Full text | PDF | PubMed
22.
Changes in the gene expression programs of renal mesangial cells during diabetic nephropathy
Eric
W
Brunskill,
S
Potter
BMC Nephrology 2012, 13 :70 (28 July 2012)
Abstract | Full text | PDF | PubMed
23.
Molecular genetic studies and delineation of the oculocutaneous albinism phenotype in the Pakistani population
Thomas
J
Jaworek,
Tasleem
Kausar,
Shannon
M
Bell,
Nabeela
Tariq,
Muhammad
Maqsood,
Asma
Sohail,
Muhmmmad
Ali,
Furhan
Iqbal,
Shafqat
Rasool,
Saima
Riazuddin,
Rehan
S
Shaikh,
Zubair
M
Ahmed
Orphanet Journal of Rare Diseases 2012, 7 :44 (26 June 2012)
Abstract | Full text | PDF | PubMed
24.
NetWalker: a contextual network analysis tool for functional genomics
Kakajan
Komurov,
Serkan
Dursun,
Serkan
Erdin,
Prahlad
T
Ram
BMC Genomics 2012, 13 :282 (25 June 2012)
Abstract | Full text | PDF | PubMed
25.
Resistin-like molecule alpha1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis
Satish
K
Madala,
Ramakrishna
Edukulla,
Katy
R
Davis,
Stephanie
Schmidt,
Cynthia
Davidson,
Joseph
A
Kitzmiller,
William
D
Hardie,
Thomas
R
Korfhagen
Respiratory Research 2012, 13 :51 (22 June 2012)
Abstract | Full text | PDF | PubMed
26.
Risk factors for cardiovascular disease and type 2 diabetes retained from childhood to adulthood predict adult outcomes: the Princeton LRC Follow-up Study
John
A
Morrison,
Charles
J
Glueck,
Jessica
G
Woo,
Ping
Wang
International Journal of Pediatric Endocrinology 2012, 2012 :6 (16 April 2012)
Abstract | Full text | PDF | PubMed
27.
Comparison of measures of marker informativeness for ancestry and admixture mapping
Lili
Ding,
Howard
Wiener,
Tilahun
Abebe,
Mekbib
Altaye,
Rodney
CP
Go,
Carolyn
Kercsmar,
Greg
Grabowski,
Lisa
J
Martin,
Gurjit
K
Khurana Hershey,
Ranajit
Chakorborty,
Tesfaye
M
Baye
BMC Genomics 2011, 12 :622 (20 December 2011)
Abstract | Full text | PDF | PubMed
28.
Zinc supplementation alters airway inflammation and airway hyperresponsiveness to a common allergen
Carrie
I
Morgan,
John
R
Ledford,
Ping
Zhou,
Kristen
Page
Journal of Inflammation 2011, 8 :36 (7 December 2011)
Abstract | Full text | PDF | PubMed
29.
Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray
Rajit
K
Basu,
Stephen
W
Standage,
Natalie
Z
Cvijanovich,
Geoffrey
L
Allen,
Neal
J
Thomas,
Robert
J
Freishtat,
Nick
Anas,
Keith
Meyer,
Paul
A
Checchia,
Richard
Lin,
Thomas
P
Shanley,
Michael
T
Bigham,
Derek
S
Wheeler,
Prasad
Devarajan,
Stuart
L
Goldstein,
Hector
R
Wong
Critical Care 2011, 15 :R273 (18 November 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
30.
Development of a validated patient-reported symptom metric for pediatric Eosinophilic Esophagitis: qualitative methods
James
P
Franciosi,
Kevin
A
Hommel,
Charles
W
DeBrosse,
Allison
B
Greenberg,
Alexandria
J
Greenler,
J Pablo
Abonia,
Marc
E
Rothenberg,
James
W
Varni
BMC Gastroenterology 2011, 11 :126 (18 November 2011)
Abstract | Full text | PDF | PubMed
31.
Inhibition of cyclo-oxygenase 2 reduces tumor metastasis and inflammatory signaling during blockade of vascular endothelial growth factor
Jason
C
Fisher,
Jeffrey
W
Gander,
Mary
Haley,
Sonia
L
Hernandez,
Jianzhong
Huang,
Yan-Jung
Chang,
Tessa
B
Johung,
Paolo
Guarnieri,
Kathleen
O'Toole,
Darrell
J
Yamashiro,
Jessica
J
Kandel
Vascular Cell 2011, 3 :22 (6 October 2011)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
A combination of COX-2 inhibition and VEGF blockade in a metastasizing orthotopic SKNEP1 model of pediatric cancer, perturbed tumour vessel remodelling and macrophage recruitment, reducing the incidence of lung metastasis.
32.
Effects of periadolescent fluoxetine and paroxetine on elevated plus-maze, acoustic startle, and swimming immobility in rats while on and off-drug
Charles
V
Vorhees,
LaRonda
R
Morford,
Devon
L
Graham,
Matthew
R
Skelton,
Michael
T
Williams
Behavioral and Brain Functions 2011, 7 :41 (5 October 2011)
Abstract | Full text | PDF | PubMed
33.
Protease-activated receptor 2 activation of myeloid dendritic cells regulates allergic airway inflammation
Ian
P
Lewkowich,
Scottie
B
Day,
John
R
Ledford,
Ping
Zhou,
Krista
Dienger,
Marsha
Wills-Karp,
Kristen
Page
Respiratory Research 2011, 12 :122 (21 September 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
34.
SHROOM3 is a novel candidate for heterotaxy identified by whole exome sequencing
Muhammad
Tariq,
John
W
Belmont,
Seema
Lalani,
Teresa
Smolarek,
Stephanie
M
Ware
Genome Biology 2011, 12 :R91 (21 September 2011)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
A recessive missense mutation in SHROOM3, which is associated with heterotaxy is identified using exome sequencing
35.
Retrospective review to determine the utility of follow-up skeletal surveys in child abuse evaluations when the initial skeletal survey is normal
Berkeley
L
Bennett,
Michael
S
Chua,
Marguerite
Care,
Andrea
Kachelmeyer,
Melinda
Mahabee-Gittens
BMC Research Notes 2011, 4 :354 (12 September 2011)
Abstract | Full text | PDF | PubMed
36.
Policy challenges for the pediatric rheumatology workforce: Part III. the international situation
Michael
Henrickson
Pediatric Rheumatology 2011, 9 :26 (12 September 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
37.
Policy challenges for the pediatric rheumatology workforce: Part I. Education and economics
Michael
Henrickson
Pediatric Rheumatology 2011, 9 :23 (16 August 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
38.
Policy challenges for the pediatric rheumatology workforce: Part II. Health care system delivery and workforce supply
Michael
Henrickson
Pediatric Rheumatology 2011, 9 :24 (15 August 2011)
Abstract | Full text | PDF | PubMed
39.
Prospero and Pax2 combinatorially control neural cell fate decisions by modulating Ras- and Notch-dependent signaling
Mark
Charlton-Perkins,
S Leigh
Whitaker,
Yueyang
Fei,
Baotong
Xie,
David
Li-Kroeger,
Brian
Gebelein,
Tiffany
Cook
Neural Development 2011, 6 :20 (3 May 2011)
Abstract | Full text | PDF | PubMed
40.
Microarrays and RNA-Seq identify molecular mechanisms driving the end of nephron production
Eric
W
Brunskill,
Hsiao
L
Lai,
D Curtis
Jamison,
S Steven
Potter,
Larry
T
Patterson
BMC Developmental Biology 2011, 11 :15 (12 March 2011)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
The completion of nephron production in mice occurs shortly after birth and is accompanied by an alteration in gene expression which occurs earlier than the decrease in Six2 expression previously linked to this process.
41.
Increased susceptibility of 129SvEvBrd mice to IgE-Mast cell mediated anaphylaxis
Muthuvel
Arumugam,
Richard
Ahrens,
Heather
Osterfeld,
Leah
C
Kottyan,
Xun
Shang,
John
A
Maclennan,
Nives
Zimmermann,
Yi
Zheng,
Fred
D
Finkelman,
Simon
P
Hogan
BMC Immunology 2011, 12 :14 (3 February 2011)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Substantial strain-dependent differences between the mast cells of 129SvEvBrd and BALB/c mice increase the susceptibility of the 129SvEvBrd mouse strain to anaphylaxis and caution should be taken when interpreting results from embryonic stem cells from this strain.
42.
Assessment of surfactant use in preterm infants as a marker of neonatal intensive care unit quality
Heather
C
Kaplan,
Scott
A
Lorch,
Jennifer
Pinto-Martin,
Mary
Putt,
Jeffrey
H
Silber
BMC Health Services Research 2011, 11 :22 (31 January 2011)
Abstract | Full text | PDF | PubMed
43.
Global gene expression profile progression in Gaucher disease mouse models
You-Hai
Xu,
Li
Jia,
Brian
Quinn,
Matthew
Zamzow,
Keith
Stringer,
Bruce
Aronow,
Ying
Sun,
Wujuan
Zhang,
Kenneth
DR
Setchell,
Gregory
A
Grabowski
BMC Genomics 2011, 12 :20 (11 January 2011)
Abstract | Full text | PDF | PubMed
44.
Frequency and spectrum of mitochondrial 12S rRNA variants in 440 Han Chinese hearing impaired pediatric subjects from two otology clinics
Zhisen
Shen,
Jing
Zheng,
Bobei
Chen,
Guanghua
Peng,
Ting
Zhang,
Shasha
Gong,
Yi
Zhu,
Chuqin
Zhang,
Ronghua
Li,
Li
Yang,
Jianjin
Zhou,
Ting
Cai,
Lihua
Jin,
Jianxin
Lu,
Min-Xin
Guan
Journal of Translational Medicine 2011, 9 :4 (4 January 2011)
Abstract | Full text | PDF | PubMed
45.
Lack of Guanylate Cyclase C results in increased mortality in mice following liver injury
Elizabeth
A
Mann,
Kumar
Shanmukhappa,
Mitchell
B
Cohen
BMC Gastroenterology 2010, 10 :86 (2 August 2010)
Abstract | Full text | PDF | PubMed