1.
Early microbial and metabolomic signatures predict later onset of necrotizing enterocolitis in preterm infants
Ardythe
L
Morrow,
Anne
J
Lagomarcino,
Kurt
R
Schibler,
Diana
H
Taft,
Zhuoteng
Yu,
Bo
Wang,
Mekibib
Altaye,
Michael
Wagner,
Dirk
Gevers,
Doyle
V
Ward,
Michael
A
Kennedy,
Curtis
Huttenhower,
David
S
Newburg
Microbiome 2013, 1 :13 (16 April 2013)
Abstract | Full text | PDF
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Editor’s summary
Abnormal gut bacteria in premature babies was found days before the onset of necrotizing enterocolitis and could also be determined indirectly from urine, providing a possible biomarker for disease.
2.
Evaluation of propofol anesthesia in morbidly obese children and adolescents
Vidya
Chidambaran,
Senthilkumar
Sadhasivam,
Jeroen
Diepstraten,
Hope
Esslinger,
Shareen
Cox,
Beverly
M
Schnell,
Paul
Samuels,
Thomas
Inge,
Alexander
A
Vinks,
Catherijne
A
Knibbe
BMC Anesthesiology 2013, 13 :8 (21 April 2013)
Abstract | Full text | PDF | PubMed
3.
Epidemiological analysis of respiratory viral etiology for influenza-like illness during 2010 in Zhuhai, China
Hongxia
Li,
Quande
Wei,
Aijun
Tan,
Leyi
Wang
Virology Journal 2013, 10 :143 (7 May 2013)
Abstract | Full text | PDF | PubMed
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Editor’s summary
A study of respiratory disease in Zhuhai, China, found seasonal patterns of influenza virus, respiratory syncytial virus, and human metapneumovirus as well as correlations between some viruses with air temperature or air humidity.
4.
Mining FDA drug labels for medical conditions
Qi
Li,
Louise
Deleger,
Todd
Lingren,
Haijun
Zhai,
Megan
Kaiser,
Laura
Stoutenborough,
Anil
G
Jegga,
Kevin Bretonnel
Cohen,
Imre
Solti
BMC Medical Informatics and Decision Making 2013, 13 :53 (24 April 2013)
Abstract | Full text | PDF | PubMed
5.
TGFβ signaling regulates lipogenesis in human sebaceous glands cells
Adrian
J
McNairn,
Yanne
Doucet,
Julien
Demaude,
Marion
Brusadelli,
Christopher
B
Gordon,
Armando
Uribe-Rivera,
Paul
F
Lambert,
Charbel
Bouez,
Lionel
Breton,
Géraldine
Guasch
BMC Dermatology 2013, 13 :2 (23 January 2013)
Abstract | Full text | PDF | PubMed
6.
The pediatric sepsis biomarker risk model
Hector
R
Wong,
Shelia
Salisbury,
Qiang
Xiao,
Natalie
Z
Cvijanovich,
Mark
Hall,
Geoffrey
L
Allen,
Neal
J
Thomas,
Robert
J
Freishtat,
Nick
Anas,
Keith
Meyer,
Paul
A
Checchia,
Richard
Lin,
Thomas
P
Shanley,
Michael
T
Bigham,
Anita
Sen,
Jeffrey
Nowak,
Michael
Quasney,
Jared
W
Henricksen,
Arun
Chopra,
Sharon
Banschbach,
Eileen
Beckman,
Kelli
Harmon,
Patrick
Lahni,
Christopher
J
Lindsell
Critical Care 2012, 16 :R174 (1 October 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
|
Editor’s summary
A biomarker-based risk model to stratify pediatric septic shock outcomes reliably identifies children at risk of death and has potential applications for clinical trial stratification, patient decision-making, and quality assurance.
7.
Functional neuronal network activity differs with cognitive dysfunction in childhood-onset systemic lupus erythematosus
Mark
W
DiFrancesco,
Darren
R
Gitelman,
Marisa
S
Klein-Gitelman,
Anna Carmela
P
Sagcal-Gironella,
Frank
Zelko,
Dean
Beebe,
Todd
Parrish,
Jessica
Hummel,
Jun
Ying,
Hermine
I
Brunner
Arthritis Research & Therapy 2013, 15 :R40 (7 March 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Functional MRI (fMRI) detection of differential neuronal network activation could be a candidate imaging biomarker for neurocognitive dysfunction (NCD) in childhood-onset systemic lupus erythematosus.
8.
Food group intake patterns and nutrient intake vary across low-income Hispanic and African American preschool children in Atlanta: a cross sectional study
Deborah
Salvo,
Jennifer
K
Frediani,
Thomas
R
Ziegler,
Conrad
R
Cole
Nutrition Journal 2012, 11 :62 (29 August 2012)
Abstract | Full text | PDF | PubMed
9.
SHROOM3 is a novel candidate for heterotaxy identified by whole exome sequencing
Muhammad
Tariq,
John
W
Belmont,
Seema
Lalani,
Teresa
Smolarek,
Stephanie
M
Ware
Genome Biology 2011, 12 :R91 (21 September 2011)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
A recessive missense mutation in SHROOM3, which is associated with heterotaxy is identified using exome sequencing
10.
Molecular genetic studies and delineation of the oculocutaneous albinism phenotype in the Pakistani population
Thomas
J
Jaworek,
Tasleem
Kausar,
Shannon
M
Bell,
Nabeela
Tariq,
Muhammad
Maqsood,
Asma
Sohail,
Muhmmmad
Ali,
Furhan
Iqbal,
Shafqat
Rasool,
Saima
Riazuddin,
Rehan
S
Shaikh,
Zubair
M
Ahmed
Orphanet Journal of Rare Diseases 2012, 7 :44 (26 June 2012)
Abstract | Full text | PDF | PubMed
11.
Resistin-like molecule alpha1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis
Satish
K
Madala,
Ramakrishna
Edukulla,
Katy
R
Davis,
Stephanie
Schmidt,
Cynthia
Davidson,
Joseph
A
Kitzmiller,
William
D
Hardie,
Thomas
R
Korfhagen
Respiratory Research 2012, 13 :51 (22 June 2012)
Abstract | Full text | PDF | PubMed
12.
Effects of periadolescent fluoxetine and paroxetine on elevated plus-maze, acoustic startle, and swimming immobility in rats while on and off-drug
Charles
V
Vorhees,
LaRonda
R
Morford,
Devon
L
Graham,
Matthew
R
Skelton,
Michael
T
Williams
Behavioral and Brain Functions 2011, 7 :41 (5 October 2011)
Abstract | Full text | PDF | PubMed
13.
A study of two Chinese patients with tetrasomy and pentasomy 15q11q13 including Prader-Willi/Angelman syndrome critical region present with developmental delays and mental impairment
Jing
Yang,
Yongchen
Yang,
Yi
Huang,
Yan
Hu,
Xi
Chen,
Hengjuan
Sun,
Zhibao
Lv,
Qian
Cheng,
Liming
Bao
BMC Medical Genetics 2013, 14 :9 (15 January 2013)
Abstract | Full text | PDF | PubMed
14.
NetWalker: a contextual network analysis tool for functional genomics
Kakajan
Komurov,
Serkan
Dursun,
Serkan
Erdin,
Prahlad
T
Ram
BMC Genomics 2012, 13 :282 (25 June 2012)
Abstract | Full text | PDF | PubMed
15.
Risk factors for cardiovascular disease and type 2 diabetes retained from childhood to adulthood predict adult outcomes: the Princeton LRC Follow-up Study
John
A
Morrison,
Charles
J
Glueck,
Jessica
G
Woo,
Ping
Wang
International Journal of Pediatric Endocrinology 2012, 2012 :6 (16 April 2012)
Abstract | Full text | PDF | PubMed
16.
Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury
Stephan
W
Glasser,
Albert
P
Senft,
Melissa
D
Maxfield,
Teah
L
Ruetschilling,
John
E
Baatz,
Kristen
Page,
Thomas
R
Korfhagen
Respiratory Research 2013, 14 :19 (12 February 2013)
Abstract | Full text | PDF | PubMed
17.
Changes in the gene expression programs of renal mesangial cells during diabetic nephropathy
Eric
W
Brunskill,
S
Potter
BMC Nephrology 2012, 13 :70 (28 July 2012)
Abstract | Full text | PDF | PubMed
18.
Low-level HIV infection of hepatocytes
Ling
Kong,
Walter
Maya,
Maria
E
Moreno-Fernandez,
Gang
Ma,
Mohamed
T
Shata,
Kenneth
E
Sherman,
Claire
Chougnet,
Jason
T
Blackard
Virology Journal 2012, 9 :157 (9 August 2012)
Abstract | Full text | PDF | PubMed
19.
Algorithm development for corticosteroid management in systemic juvenile idiopathic arthritis trial using consensus methodology
Norman
T
Ilowite,
Christy
I
Sandborg,
Brian
M
Feldman,
Alexi
Grom,
Laura
E
Schanberg,
Edward
H
Giannini,
Carol
A
Wallace,
Rayfel
Schneider,
Kathleen
Kenney,
Beth
Gottlieb,
Philip
J
Hashkes,
Lisa
Imundo,
Yukiko
Kimura,
Bianca
Lang,
Michael
Miller,
Diana
Milojevic,
Kathleen
M
O’Neil,
Marilynn
Punaro,
Natasha
Ruth,
Nora
G
Singer,
Richard
K
Vehe,
James
Verbsky,
Amy
Woodward,
Lawrence
Zemel
Pediatric Rheumatology 2012, 10 :31 (29 August 2012)
Abstract | Full text | PDF | PubMed
20.
Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children
Hector
R
Wong,
Natalie
Z
Cvijanovich,
Mark
Hall,
Geoffrey
L
Allen,
Neal
J
Thomas,
Robert
J
Freishtat,
Nick
Anas,
Keith
Meyer,
Paul
A
Checchia,
Richard
Lin,
Michael
T
Bigham,
Anita
Sen,
Jeffrey
Nowak,
Michael
Quasney,
Jared
W
Henricksen,
Arun
Chopra,
Sharon
Banschbach,
Eileen
Beckman,
Kelli
Harmon,
Patrick
Lahni,
Thomas
P
Shanley
Critical Care 2012, 16 :R213 (29 October 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
21.
Prolonged FGF signaling is necessary for lung and liver induction in Xenopus
Emily
T
Shifley,
Alan
P
Kenny,
Scott
A
Rankin,
Aaron
M
Zorn
BMC Developmental Biology 2012, 12 :27 (18 September 2012)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Fibroblast Growth Factor (FGF) signaling from the mesoderm is required to induce liver and lung development in Xenopus with the duration of this signal, rather than the strength, important for full differentiation of these organs
22.
The role of protease-activated receptor-2 on pulmonary neutrophils in the innate immune response to cockroach allergen
Riad
Lutfi,
Ian
P
Lewkowich,
Ping
Zhou,
John
R
Ledford,
Kristen
Page
Journal of Inflammation 2012, 9 :32 (6 September 2012)
Abstract | Full text | PDF | PubMed
23.
Policy challenges for the pediatric rheumatology workforce: Part I. Education and economics
Michael
Henrickson
Pediatric Rheumatology 2011, 9 :23 (16 August 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
24.
Protease-activated receptor 2 activation of myeloid dendritic cells regulates allergic airway inflammation
Ian
P
Lewkowich,
Scottie
B
Day,
John
R
Ledford,
Ping
Zhou,
Krista
Dienger,
Marsha
Wills-Karp,
Kristen
Page
Respiratory Research 2011, 12 :122 (21 September 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
25.
Inhibition of cyclo-oxygenase 2 reduces tumor metastasis and inflammatory signaling during blockade of vascular endothelial growth factor
Jason
C
Fisher,
Jeffrey
W
Gander,
Mary
Haley,
Sonia
L
Hernandez,
Jianzhong
Huang,
Yan-Jung
Chang,
Tessa
B
Johung,
Paolo
Guarnieri,
Kathleen
O'Toole,
Darrell
J
Yamashiro,
Jessica
J
Kandel
Vascular Cell 2011, 3 :22 (6 October 2011)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
A combination of COX-2 inhibition and VEGF blockade in a metastasizing orthotopic SKNEP1 model of pediatric cancer, perturbed tumour vessel remodelling and macrophage recruitment, reducing the incidence of lung metastasis.