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Member - International Institute of Molecular and Cell Biology

International Institute of Molecular and Cell Biology hosts nine laboratories involved in molecular and cellular research: cancer and structural biology, neurobiology, intracellular communication, dendritic tree formation, bioinformatics, enzyme engineering, and mitochondrial biogenesis.

www.iimcb.gov.pl

Research staff and students at International Institute of Molecular and Cell Biology:

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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at International Institute of Molecular and Cell Biology

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	1.	Software RNAmap2D – calculation, visualization and analysis of contact and distance maps for RNA and protein-RNA complex structures Michal J Pietal, Natalia Szostak, Kristian M Rother, Janusz M Bujnicki BMC Bioinformatics 2012, 13:333 (21 December 2012) Abstract \| Full text \| PDF \| PubMed
	2.	Research article Novel β-catenin target genes identified in thalamic neurons encode modulators of neuronal excitability Marta B Wisniewska, Andrzej Nagalski, Michal Dabrowski, Katarzyna Misztal, Jacek Kuznicki BMC Genomics 2012, 13:635 (17 November 2012) Abstract \| Full text \| PDF \| PubMed
	3.	Poster presentation *Targeted testing for DNAI1* hot spot-mutation utilizing immunofluorescence microscopy findings** M Szczepaniak, NT Loges, H Olbrich, M Witt, H Omran Cilia 2012, 1(Suppl 1):P104 (16 November 2012) Full text \| PDF
	4.	Research article The utility of comparative models and the local model quality for protein crystal structure determination by Molecular Replacement Marcin Pawlowski, Janusz M Bujnicki BMC Bioinformatics 2012, 13:289 (5 November 2012) Abstract \| Full text \| PDF \| PubMed
	5.	Research article Oral anticoagulant and antiplatelet drugs used in prevention of cardiovascular events in elderly people in Poland Beata Labuz-Roszak, Krystyna Pierzchala, Michal Skrzypek, Marta Swiech, Agnieszka Machowska-Majchrzak BMC Cardiovascular Disorders 2012, 12:98 (31 October 2012) Abstract \| Full text \| PDF \| PubMed
	6.	Research article Molecular evolution of dihydrouridine synthases Joanna M Kasprzak, Anna Czerwoniec, Janusz M Bujnicki BMC Bioinformatics 2012, 13:153 (28 June 2012) Abstract \| Full text \| PDF \| PubMed
	7.	Research article Anti-staphylococcal activities of lysostaphin and LytM catalytic domain Izabela Sabala, Ing-Marie Jonsson, Andrej Tarkowski, Matthias Bochtler BMC Microbiology 2012, 12:97 (6 June 2012) Abstract \| Full text \| PDF \| PubMed
	8.	Research article MetaDisorder: a meta-server for the prediction of intrinsic disorder in proteins Lukasz P Kozlowski, Janusz M Bujnicki BMC Bioinformatics 2012, 13:111 (24 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	9.	Research article Related bifunctional restriction endonuclease-methyltransferase triplets: TspDTI, Tth111II/TthHB27I and TsoI with distinct specificities Agnieszka Zylicz-Stachula, Olga Zolnierkiewicz, Arvydas Lubys, Danute Ramanauskaite, Goda Mitkaite, Janusz M Bujnicki, Piotr M Skowron BMC Molecular Biology 2012, 13:13 (10 April 2012) Abstract \| Full text \| PDF \| PubMed
	10.	Correction Correction: Cell death upon epigenetic genome methylation: a novel function of methyl-specific deoxyribonucleases Eri Fukuda, Katarzyna H Kaminska, Janusz M Bujnicki, Ichizo Kobayashi Genome Biology 2011, 12:412 (15 January 2012) Abstract \| Full text \| PDF
	11.	Software DARS-RNP and QUASI-RNP: New statistical potentials for protein-RNA docking Irina Tuszynska, Janusz M Bujnicki BMC Bioinformatics 2011, 12:348 (18 August 2011) Abstract \| Full text \| PDF \| PubMed
	12.	Research *Population specificity of the DNAI1* gene mutation spectrum in primary ciliary dyskinesia (PCD)** Ewa Ziętkiewicz, Barbara Nitka, Katarzyna Voelkel, Urszula Skrzypczak, Zuzanna Bukowy, Ewa Rutkiewicz, Kinga Humińska, Hanna Przystałowska, Andrzej Pogorzelski, Michał Witt Respiratory Research 2010, 11:174 (8 December 2010) Abstract \| Full text \| PDF \| PubMed
	13.	Research Mitochondrial genotype in vulvar carcinoma - cuckoo in the nest Aleksandra Klemba, Magdalena Kowalewska, Wojciech Kukwa, Katarzyna Tonska, Aleksandra Szybinska, Malgorzata Mossakowska, Anna Scinska, Paweł Golik, Kamil Koper, Jakub Radziszewski, Andrzej Kukwa, Anna M Czarnecka, Ewa Bartnik Journal of Biomedical Science 2010, 17:73 (8 September 2010) Abstract \| Full text \| PDF \| PubMed
	14.	Research The new platinum(IV) derivative LA-12 shows stronger inhibitory effect on Hsp90 function compared to cisplatin Veronika Kvardova, Roman Hrstka, Dawid Walerych, Petr Muller, Eva Matoulkova, Veronika Hruskova, Dagmar Stelclova, Petr Sova, Borivoj Vojtesek Molecular Cancer 2010, 9:147 (15 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	15.	Research The dissection of transcriptional modules regulated by various drugs of abuse in the mouse striatum Marcin Piechota, Michal Korostynski, Wojciech Solecki, Agnieszka Gieryk, Michal Slezak, Wiktor Bilecki, Barbara Ziolkowska, Elzbieta Kostrzewa, Iwona Cymerman, Lukasz Swiech, Jacek Jaworski, Ryszard Przewlocki Genome Biology 2010, 11:R48 (4 May 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The transcriptional response to six commonly-abused drugs was assessed in the mouse brain revealing common modules of drug-induced genes.
	16.	Research article *Cloning and analysis of a bifunctional methyltransferase/restriction endonuclease TspGWI, the prototype of a Thermus* sp. enzyme family** Agnieszka Zylicz-Stachula, Janusz M Bujnicki, Piotr M Skowron BMC Molecular Biology 2009, 10:52 (29 May 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	17.	Short Report Medaka: a promising model animal for comparative population genomics Yoshifumi Matsumoto, Hiroki Oota, Yoichi Asaoka, Hiroshi Nishina, Koji Watanabe, Janusz M Bujnicki, Shoji Oda, Shoji Kawamura, Hiroshi Mitani BMC Research Notes 2009, 2:88 (10 May 2009) Abstract \| Full text \| PDF \| PubMed
	18.	Research Cell death upon epigenetic genome methylation: a novel function of methyl-specific deoxyribonucleases Eri Fukuda, Katarzyna H Kaminska, Janusz M Bujnicki, Ichizo Kobayashi Genome Biology 2008, 9:R163 (21 November 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The McrBC methyl-specific deoxyribonuclease from Escherichia coli can respond to genome methylation by host killing.
	19.	Research article Type II restriction endonuclease R.Hpy188I belongs to the GIY-YIG nuclease superfamily, but exhibits an unusual active site Katarzyna H Kaminska, Mikihiko Kawai, Michal Boniecki, Ichizo Kobayashi, Janusz M Bujnicki BMC Structural Biology 2008, 8:48 (14 November 2008) Abstract \| Full text \| PDF \| PubMed
	20.	Software MetaMQAP: A meta-server for the quality assessment of protein models Marcin Pawlowski, Michal J Gajda, Ryszard Matlak, Janusz M Bujnicki BMC Bioinformatics 2008, 9:403 (29 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	21.	Research article Type II restriction endonuclease R.Eco29kI is a member of the GIY-YIG nuclease superfamily Elena M Ibryashkina, Marina V Zakharova, Vladimir B Baskunov, Ekaterina S Bogdanova, Maxim O Nagornykh, Marat M Den'mukhamedov, Bogdan S Melnik, Andrzej Kolinski, Dominik Gront, Marcin Feder, Alexander S Solonin, Janusz M Bujnicki BMC Structural Biology 2007, 7:48 (12 July 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The type II restriction endonuclease R.Eco29kI belongs to the GIY-YIG superfamily of DNA-cleaving enzymes, and so is unrelated to all other restriction endonucleases studied to date.
	22.	Research article Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases Karolina L Tkaczuk, Stanislaw Dunin-Horkawicz, Elzbieta Purta, Janusz M Bujnicki BMC Bioinformatics 2007, 8:73 (5 March 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23.	Research article *The yfhQ* gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase** Elzbieta Purta, Françoise van Vliet, Karolina L Tkaczuk, Stanislaw Dunin-Horkawicz, Hirotada Mori, Louis Droogmans, Janusz M Bujnicki BMC Molecular Biology 2006, 7:23 (18 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	24.	Research article Phylogenomic analysis of the GIY-YIG nuclease superfamily Stanislaw Dunin-Horkawicz, Marcin Feder, Janusz M Bujnicki BMC Genomics 2006, 7:98 (28 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	25.	Research article Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis Karolina L Tkaczuk, Agnieszka Obarska, Janusz M Bujnicki BMC Evolutionary Biology 2006, 6:6 (24 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Phylogenetic and fold-recognition analysis of homologs of HEN1, a key enzyme in plant microRNA biogenesis, yields a structural model of the catalytic domain and reveals HEN1 to be related to small-molecule methyltransferases.