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1.

Research   Open Access

Toxicity and outcomes of thoracic re-irradiation using stereotactic body radiation therapy (SBRT)

Marsha Reyngold, Abraham J Wu, Amanda McLane, Zhigang Zhang, Meier Hsu, Nicholas F Stein, Ying Zhou, Alice Y Ho, Kenneth E Rosenzweig, Ellen D Yorke, Andreas Rimner Radiation Oncology 2013, 8:99 (25 April 2013)

Abstract | Full text | PDF | PubMed

2.

Methodology article   Open Access

A bright single-cell resolution live imaging reporter of Notch signaling in the mouse

Sonja Nowotschin, Panagiotis Xenopoulos, Nadine Schrode, Anna-Katerina Hadjantonakis BMC Developmental Biology 2013, 13:15 (25 April 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

Transgenic mice expressing a nuclear-localized fluorescent protein driven by responsive elements, taken from the CBF1 transcription factor, allow single-cell resolution of the Notch signaling pathway, with greater sensitivity and resolution than previous reporter lines.  

3.

Viewpoint   Subscription

Activating mutations and senescence secretome: new insights into HER2 activation, drug sensitivity and metastatic progression

Swarnali Acharyya Breast Cancer Research 2013, 15:309 (23 April 2013)

Abstract | Full text | PDF | PubMed

4.

Proceedings   Open Access

An optimized algorithm for detecting and annotating regional differential methylation

Sheng Li, Francine E Garrett-Bakelman, Altuna Akalin, Paul Zumbo, Ross Levine, Bik L To, Ian D Lewis, Anna L Brown, Richard J D'Andrea, Ari Melnick, Christopher E Mason BMC Bioinformatics 2013, 14(Suppl 5):S10 (10 April 2013)

Abstract | Full text | PDF

5.

Research article   Open Access Highly Accessed

Vaccinia virus GLV-1h153 is a novel agent for detection and effective local control of positive surgical margins for breast cancer

Sepideh Gholami, Chun-Hao Chen, Laurence J Belin, Emil Lou, Sho Fujisawa, Caroline Antonacci, Amanda Carew, Nanhai G Chen, Marina De Brot, Pat B Zanzonico, Aladar A Szalay, Yuman Fong Breast Cancer Research 2013, 15:R26 (18 March 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

Oncolytic vaccinia virus, GLV1h-153, engineered to express the human sodium iodide symporter (hNIS) gene is useful in imaging cancers and can be used to identify and treat positive surgical margins of breast cancer in mice.

6.

Research article   Open Access

Embryonic mammary signature subsets are activated in Brca1-/- and basal-like breast cancers

Marketa Zvelebil, Erik Oliemuller, Qiong Gao, Olivia Wansbury, Alan Mackay, Howard Kendrick, Matthew J Smalley, Jorge S Reis-Filho, Beatrice A Howard Breast Cancer Research 2013, 15:R25 (18 March 2013)

Abstract | Full text | PDF | PubMed

7.

Oral presentation   Open Access

Using the lagging strand to study chromosome replication

S McGuffee, D Smith, I Whitehouse Epigenetics & Chromatin 2013, 6(Suppl 1):O2 (18 March 2013)

Full text | PDF

8.

Research   Open Access

Health-related quality of life and life satisfaction in colorectal cancer survivors: trajectories of adjustment

Jeff Dunn, Shu Ng, William Breitbart, Joanne Aitken, Pip Youl, Peter D Baade, Suzanne K Chambers Health and Quality of Life Outcomes 2013, 11:46 (14 March 2013)

Abstract | Full text | PDF | PubMed

9.

Research   Open Access

SSX2IP promotes metastasis and chemotherapeutic resistance of hepatocellular carcinoma

Pu Li, Ying Lin, Yu Zhang, Zhenggang Zhu, Keke Huo Journal of Translational Medicine 2013, 11:52 (1 March 2013)

Abstract | Full text | PDF | PubMed

10.

Research article   Open Access Highly Accessed

Sugary food and beverage consumption and epithelial ovarian cancer risk: a population-based case–control study

Melony G King, Sara H Olson, Lisa Paddock, Urmila Chandran, Kitaw Demissie, Shou-En Lu, Niyati Parekh, Lorna Rodriguez-Rodriguez, Elisa V Bandera BMC Cancer 2013, 13:94 (27 February 2013)

Abstract | Full text | PDF | PubMed

11.

Research   Open Access

Age matters:  Young T lymphocytes offer better protection from myeloma proliferation

Alexander F Glick, Yan S Song, Brian Hwang, John Lillvis, Pat Zanzonico, Camil Fuchs, Roger N Pearse, Paul Szabo, Marc E Weksler Immunity & Ageing 2013, 10:5 (18 February 2013)

Abstract | Full text | PDF | PubMed

12.

Research   Open Access

Radiation therapy for epithelial ovarian cancer brain metastases: clinical outcomes and predictors of survival

Sewit Teckie, Vicky Makker, Viviane Tabar, Kaled Alektiar, Carol Aghajanian, Martee Hensley, Kathryn Beal Radiation Oncology 2013, 8:36 (15 February 2013)

Abstract | Full text | PDF | PubMed

13.

Review   Open Access

Complex roles of filamin-A mediated cytoskeleton network in cancer progression

Jingyin Yue, Steven Huhn, Zhiyuan Shen Cell & Bioscience 2013, 3:7 (6 February 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

14.

Research article   Open Access Highly Accessed

Recent alcohol consumption and risk of incident ovarian carcinoma: a pooled analysis of 5,342 cases and 10,358 controls from the Ovarian Cancer Association Consortium

Linda E Kelemen, Elisa V Bandera, Kathryn L Terry, Mary Anne Rossing, Louise A Brinton, Jennifer A Doherty, Roberta B Ness, Susanne Krüger Kjær, Jenny Chang-Claude, Martin Köbel, Galina Lurie, Pamela J Thompson, Michael E Carney, Kirsten Moysich, Robert Edwards, Clare Bunker, Allan Jensen, Estrid Høgdall, Daniel W Cramer, Allison F Vitonis, Sara H Olson, Melony King, Urmila Chandran, Jolanta Lissowska, Montserrat Garcia-Closas, Hannah Yang, Penelope M Webb, Joellen M Schildkraut, Marc T Goodman, Harvey A Risch, BMC Cancer 2013, 13:28 (22 January 2013)

Abstract | Full text | PDF | PubMed

15.

Research article   Open Access

Disentangling function from topology to infer the network properties of disease genes

Dario Ghersi, Mona Singh BMC Systems Biology 2013, 7:5 (16 January 2013)

Abstract | Full text | PDF | PubMed

16.

Research   Open Access

Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data

Matthew Parker, Xiang Chen, Armita Bahrami, James Dalton, Michael Rusch, Gang Wu, John Easton, Nai-Kong Cheung, Michael Dyer, Elaine R Mardis, Richard K Wilson, Charles Mullighan, Richard Gilbertson, Suzanne J Baker, Gerard Zambetti, David W Ellison, James R Downing, Jinghui Zhang, Genome Biology 2012, 13:R113 (11 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A comprehensive analysis of telomere length changes in a large collection of pediatric tumors

17.

Research article   Open Access

Actomyosin-based Self-organization of cell internalization during C. elegans gastrulation

Christian Pohl, Michael Tiongson, Julia L Moore, Anthony Santella, Zhirong Bao BMC Biology 2012, 10:94 (30 November 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A time-lapse imaging study in C. elegans shows how self-organizing modules form rosettes to remodel the embryo through actomyosin-based patterning during gastrulation.

18.

Poster presentation   Open Access

The functional relationships between BBS and MKS and their role in regulating trafficking of proteins in the primary cilium

F Bangs, S Goetz, KV Anderson Cilia 2012, 1(Suppl 1):P62 (16 November 2012)

Full text | PDF

19.

Oral presentation   Open Access

Genetic analysis of cilia and centrosome function in the development of the mouse embryo

KV Anderson, B Bazzi Cilia 2012, 1(Suppl 1):O19 (16 November 2012)

Full text | PDF

20.

Oral presentation   Open Access

Tau tubulin kinase 2 is required to initiate mammalian ciliogenesis

S Goetz, KV Anderson Cilia 2012, 1(Suppl 1):O18 (16 November 2012)

Full text | PDF

21.

Research article   Open Access

Molecular characterisation of cell line models for triple-negative breast cancers

Anita Grigoriadis, Alan Mackay, Elodie Noel, Pei Wu, Rachel Natrajan, Jessica Frankum, Jorge S Reis-Filho, Andrew Tutt BMC Genomics 2012, 13:619 (14 November 2012)

Abstract | Full text | PDF | PubMed

22.

Case Report   Open Access

Pulmonary artery sarcoma with angiosarcoma phenotype mimicking pleomorphic malignant fibrous histiocytoma: a case report

Olga L Bohn, Eric de León, Oscar Lezama, Nina P Rios-Luna, Sergio Sánchez-Sosa, Antonio Llombart-Bosch Diagnostic Pathology 2012, 7:154 (7 November 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

23.

Research article   Open Access

External validation of the Bayesian Estimated Tools for Survival (BETS) models in patients with surgically treated skeletal metastases

Jonathan Agner Forsberg, Rikard Wedin, Henrik CF Bauer, Bjarne H Hansen, Minna Laitinen, Clement S Trovik, Johnny Ø Keller, Patrick J Boland, John H Healey BMC Cancer 2012, 12:493 (25 October 2012)

Abstract | Full text | PDF | PubMed

24.

Research article   Open Access

Awareness of the 2009 US Preventive Services Task Force recommended changes in mammography screening guidelines, accuracy of awareness, sources of knowledge about recommendations, and attitudes about updated screening guidelines in women ages 40–49 and 50+

Marc T Kiviniemi, Jennifer L Hay BMC Public Health 2012, 12:899 (24 October 2012)

Abstract | Full text | PDF | PubMed

25.

Research   Open Access Highly Accessed

Outcome and patterns of failure after postoperative intensity modulated radiotherapy for locally advanced or high-risk oral cavity squamous cell carcinoma

Andreas Geretschläger, Beat Bojaxhiu, Susanne Crowe, Andreas Arnold, Peter Manser, Wock Hallermann, Daniel M Aebersold, Pirus Ghadjar Radiation Oncology 2012, 7:175 (22 October 2012)

Abstract | Full text | PDF | PubMed

26.

Review   Open Access Highly Accessed

Inherited gastrointestinal stromal tumor syndromes: mutations, clinical features, and therapeutic implications

Michael A Postow, Mark E Robson Clinical Sarcoma Research 2012, 2:16 (4 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

27.

Review   Open Access Highly Accessed

Cancer classification using the Immunoscore: a worldwide task force

Jérôme Galon, Franck Pagès, Francesco M Marincola, Helen K Angell, Magdalena Thurin, Alessandro Lugli, Inti Zlobec, Anne Berger, Carlo Bifulco, Gerardo Botti, Fabiana Tatangelo, Cedrik M Britten, Sebastian Kreiter, Lotfi Chouchane, Paolo Delrio, Hartmann Arndt, Martin Asslaber, Michele Maio, Giuseppe V Masucci, Martin Mihm, Fernando Vidal-Vanaclocha, James P Allison, Sacha Gnjatic, Leif Hakansson, Christoph Huber, Harpreet Singh-Jasuja, Christian Ottensmeier, Heinz Zwierzina, Luigi Laghi, Fabio Grizzi et al. Journal of Translational Medicine 2012, 10:205 (3 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

28.

Research   Open Access

Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity

Alok K Tewari, Galip Yardimci, Yoichiro Shibata, Nathan C Sheffield, Lingyun Song, Barry S Taylor, Stoyan G Georgiev, Gerhard A Coetzee, Uwe Ohler, Terrence S Furey, Gregory E Crawford, Phillip G Febbo Genome Biology 2012, 13:R88 (3 October 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Androgen receptor binding to the genome occurs by multiple mechanisms and is associated with an increase in chromatin accessibility

29.

Review   Open Access Highly Accessed

ACR Appropriateness Criteria®  Resectable Rectal Cancer

William E Jones, Charles R Thomas, Joseph M Herman, May Abdel-Wahab, Nilofer Azad, William Blackstock, Prajnan Das, Karyn A Goodman, Theodore S Hong, Salma K Jabbour, Andre A Konski, Albert C Koong, Miguel Rodriguez-Bigas, William Small, Jennifer Zook, W Suh Radiation Oncology 2012, 7:161 (24 September 2012)

Abstract | Full text | PDF | PubMed

30.

Research   Open Access Highly Accessed

microRNA-146a inhibits G protein-coupled receptor-mediated activation of NF-κB by targeting CARD10 and COPS8 in gastric cancer

Stephanie Crone, Anders Jacobsen, Birgitte Federspiel, Linda Bardram, Anders Krogh, Anders H Lund, Lennart Friis-Hansen Molecular Cancer 2012, 11:71 (20 September 2012)

Abstract | Full text | PDF | PubMed

31.

Research article   Open Access Highly Accessed

SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors

Antoine Italiano, Chun-Liang Chen, Yun-Shao Sung, Samuel Singer, Ronald P DeMatteo, Michael P LaQuaglia, Peter Besmer, Nicholas Socci, Cristina R Antonescu BMC Cancer 2012, 12:408 (14 September 2012)

Abstract | Full text | PDF | PubMed

32.

Research   Open Access Highly Accessed

Clinically significant bleeding in incurable cancer patients: effectiveness of hemostatic radiotherapy

Nikola Cihoric, Susanne Crowe, Steffen Eychmüller, Daniel M Aebersold, Pirus Ghadjar Radiation Oncology 2012, 7:132 (3 August 2012)

Abstract | Full text | PDF | PubMed

33.

Research article   Open Access

Dynamic tumor modeling of the dose–response relationship for everolimus in metastatic renal cell carcinoma using data from the phase 3 RECORD-1 trial

Andrew Stein, Wenping Wang, Alison A Carter, Ovidiu Chiparus, Norbert Hollaender, Hyewon Kim, Robert J Motzer, Celine Sarr BMC Cancer 2012, 12:311 (23 July 2012)

Abstract | Full text | PDF | PubMed

34.

Research article   Open Access Highly Accessed

Comparison of oral microbiota in tumor and non-tumor tissues of patients with oral squamous cell carcinoma

Smruti Pushalkar, Xiaojie Ji, Yihong Li, Cherry Estilo, Ramanathan Yegnanarayana, Bhuvanesh Singh, Xin Li, Deepak Saxena BMC Microbiology 2012, 12:144 (20 July 2012)

Abstract | Full text | PDF | PubMed

35.

Research article   Open Access

Clonal relatedness between lobular carcinoma in situ and synchronous malignant lesions

Victor P Andrade, Irina Ostrovnaya, Venkatraman E Seshan, Mary Morrogh, Dilip Giri, Narciso Olvera, Marina De Brot, Monica Morrow, Colin B Begg, Tari A King Breast Cancer Research 2012, 14:R103 (9 July 2012)

Abstract | Full text | PDF | PubMed

36.

Review   Open Access Highly Accessed

Considerations in the development of circulating tumor cell technology for clinical use

David R Parkinson, Nicholas Dracopoli, Brenda Petty, Carolyn Compton, Massimo Cristofanilli, Albert Deisseroth, Daniel F Hayes, Gordon Kapke, Prasanna Kumar, Jerry SH Lee, Minetta C Liu, Robert McCormack, Stanislaw Mikulski, Larry Nagahara, Klaus Pantel, Sonia Pearson-White, Elizabeth A Punnoose, Lori T Roadcap, Andrew E Schade, Howard I Scher, Caroline C Sigman, Gary J Kelloff Journal of Translational Medicine 2012, 10:138 (2 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

37.

Research article   Open Access

Physical activity reduces risk for colon polyps in a multiethnic colorectal cancer screening population

Nelson F Sanchez, Bryan Stierman, Said Saab, Divya Mahajan, Howa Yeung, Fritz Francois BMC Research Notes 2012, 5:312 (20 June 2012)

Abstract | Full text | PDF | PubMed

38.

Research article   Open Access Highly Accessed

MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells

Lea H Gregersen, Anders Jacobsen, Lisa B Frankel, Jiayu Wen, Anders Krogh, Anders H Lund BMC Cancer 2012, 12:232 (12 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

39.

Oral presentation   Open Access

OA03.01. Acupuncture for chronic pain: an individual patient data meta-analysis of randomized trials

A Vickers, A Cronin, A Maschino, G Lewith, H MacPherson, N Victor, N Foster, K Sherman, C Witt, K Linde BMC Complementary and Alternative Medicine 2012, 12(Suppl 1):O9 (12 June 2012)

Full text | PDF

40.

Research article   Open Access Highly Accessed

Total and individual antioxidant intake and risk of epithelial ovarian cancer

Dina Gifkins, Sara H Olson, Lisa Paddock, Melony King, Kitaw Demissie, Shou-En Lu, Ah-Ng Kong, Lorna Rodriguez-Rodriguez, Elisa V Bandera BMC Cancer 2012, 12:211 (1 June 2012)

Abstract | Full text | PDF | PubMed

41.

Poster presentation   Open Access

Ras-driven cancer cells can scavenge exogenous lipids to support their proliferation

Jurre J Kamphorst, Justin R Cross, Jing Fan, Wenyun Lu, Eileen White, Craig B Thompson, Joshua D Rabinowitz BMC Proceedings 2012, 6(Suppl 3):P25 (1 June 2012)

Full text | PDF

42.

Oral presentation   Open Access

Beyond insulin: rethinking cellular metabolism

Craig B Thompson BMC Proceedings 2012, 6(Suppl 3):O25 (1 June 2012)

Full text | PDF

43.

Poster presentation   Open Access

The role of SIRT3 in regulating cancer cell metabolism

Karina N Gonzalez Herrera, Lydia W Finley, Marcia C Haigis BMC Proceedings 2012, 6(Suppl 3):P18 (1 June 2012)

Full text | PDF

44.

Research article   Open Access

Immune Mediators of protective and pathogenic immune responses in patients with mild and fatal human monocytotropic ehrlichiosis

Nahed Ismail, David H Walker, Purnima Ghose, Yi-Wei Tang BMC Immunology 2012, 13:26 (21 May 2012)

Abstract | Full text | PDF | PubMed

45.

Research article   Open Access

PAD4 is not essential for disease in the K/BxN murine autoantibody-mediated model of arthritis

Amanda S Rohrbach, Saskia Hemmers, Sanja Arandjelovic, Maripat Corr, Kerri A Mowen Arthritis Research & Therapy 2012, 14:R104 (2 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

46.

Research   Open Access

Lymph-node ratio is an independent prognostic factor in patients with stage III colorectal cancer: a retrospective study from the Middle East

Elias Elias, Deborah Mukherji, Walid Faraj, Mohammad Khalife, Hani Dimassi, Mohamad Eloubeidi, Hasan Hattoum, Ghassan K Abou‒Alfa, Ahmad Saleh, Ali Shamseddine World Journal of Surgical Oncology 2012, 10:63 (25 April 2012)

Abstract | Full text | PDF | PubMed

47.

Research article   Open Access

Genome-wide analysis of Pax8 binding provides new insights into thyroid functions

Sergio Ruiz-Llorente, Enrique Carrillo de Pau, Ana Sastre-Perona, Cristina Montero-Conde, Gonzalo Gómez-López, James A Fagin, Alfonso Valencia, David G Pisano, Pilar Santisteban BMC Genomics 2012, 13:147 (24 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

48.

Oral presentation   Open Access

A phase 1/PK study of Sunitinib with highly active antiretroviral therapy (HAART) in HIV+ patients with solid tumors: AIDS malignancy consortium study 061

John F Deeken, Michelle A Rudek, Page C Moore, David Aboulafia, Ryan Sullivan, John Gerecitano, Mary Cianfrocca, David Henry, Lee Ratner, Bruce Dezube, Kimberly Mosby, Melinda Tibbals, Richard F Little, S P Ivy, Ronald T Mitsuyasu Infectious Agents and Cancer 2012, 7(Suppl 1):O15 (19 April 2012)

Full text | PDF

49.

Oral presentation   Open Access

Modified dose intensive R- CODOX-M/IVAC for HIV-associated burkitt (BL) (AMC 048) shows efficacy and tolerability, and predictive potential of IRF4/MUM1 expression

Ariela Noy, Lawrence Kaplan, Jeannette Lee, Ethel Cesarman, Wayne Tam Infectious Agents and Cancer 2012, 7(Suppl 1):O14 (19 April 2012)

Full text | PDF

50.

Review   Open Access

Roles of Polo-like kinase 3 in suppressing tumor angiogenesis

Dazhong Xu, Qi Wang, Yongping Jiang, Yanxi Zhang, Eleazar Vega-SaenzdeMiera, Iman Osman, Wei Dai Experimental Hematology & Oncology 2012, 1:5 (18 April 2012)

Abstract | Full text | PDF

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