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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at Memorial Sloan Kettering Cancer Center

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	1.	Research article Parametric versus non-parametric statistics in the analysis of randomized trials with non-normally distributed data Andrew J Vickers BMC Medical Research Methodology 2005, 5:35 (3 November 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments \| Editor’s summary Analysis of simulated data reveals that ANCOVA should be the preferred method for analyzing randomized trials with pre-test and post-test measures and non-normally distributed data, but in cases with extreme skew, Mann-Whitney was preferred.
	2.	Method Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites Doron Betel, Anjali Koppal, Phaedra Agius, Chris Sander, Christina Leslie Genome Biology 2010, 11:R90 (27 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary mirSVR is a method for miRNA target prediction that, unusually, takes into account non-canonical binding sequences and non-conserved sites
	3.	Research article The use of percentage change from baseline as an outcome in a controlled trial is statistically inefficient: a simulation study Andrew J Vickers BMC Medical Research Methodology 2001, 1:6 (28 June 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	4.	Commentary Defining the critical hurdles in cancer immunotherapy Bernard A Fox, Dolores J Schendel, Lisa H Butterfield, Steinar Aamdal, James P Allison, Paolo Ascierto, Michael B Atkins, Jirina Bartunkova, Lothar Bergmann, Neil Berinstein, Cristina C Bonorino, Ernest Borden, Jonathan L Bramson, Cedrik M Britten, Xuetao Cao, William E Carson, Alfred E Chang, Dainius Characiejus, A Raja Choudhury, George Coukos, Tanja de Gruijl, Robert O Dillman, Harry Dolstra, Glenn Dranoff, Lindy G Durrant, James H Finke, Jerome Galon, Jared A Gollob, Cécile Gouttefangeas, Fabio Grizzi et al. Journal of Translational Medicine 2011, 9:214 (14 December 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	5.	Research Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity Alok K Tewari, Galip Yardimci, Yoichiro Shibata, Nathan C Sheffield, Lingyun Song, Barry S Taylor, Stoyan G Georgiev, Gerhard A Coetzee, Uwe Ohler, Terrence S Furey, Gregory E Crawford, Phillip G Febbo Genome Biology 2012, 13:R88 (3 October 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Androgen receptor binding to the genome occurs by multiple mechanisms and is associated with an increase in chromatin accessibility
	6.	Review Considerations in the development of circulating tumor cell technology for clinical use David R Parkinson, Nicholas Dracopoli, Brenda Petty, Carolyn Compton, Massimo Cristofanilli, Albert Deisseroth, Daniel F Hayes, Gordon Kapke, Prasanna Kumar, Jerry SH Lee, Minetta C Liu, Robert McCormack, Stanislaw Mikulski, Larry Nagahara, Klaus Pantel, Sonia Pearson-White, Elizabeth A Punnoose, Lori T Roadcap, Andrew E Schade, Howard I Scher, Caroline C Sigman, Gary J Kelloff Journal of Translational Medicine 2012, 10:138 (2 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	7.	Research MicroRNA targets in Drosophila Anton J Enright, Bino John, Ulrike Gaul, Thomas Tuschl, Chris Sander, Debora S Marks Genome Biology 2003, 5:R1 (12 December 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary A computational method for whole-genome prediction of microRNA target genes is presented. Application of this method to the Drosophila melanogaster, Drosophila pseudoobscura and Anopheles gambiae genomes identifies several hundred target genes potentially regulated by one or more known microRNAs.
	8.	Research article Cerebellum morphogenesis: the foliation pattern is orchestrated by multi-cellular anchoring centers Anamaria Sudarov, Alexandra L Joyner Neural Development 2007, 2:26 (3 December 2007) Abstract \| Full text \| PDF \| PubMed
	9.	Methodology article An automated method for finding molecular complexes in large protein interaction networks Gary D Bader, Christopher WV Hogue BMC Bioinformatics 2003, 4:2 (13 January 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	10.	Review Cancer classification using the Immunoscore: a worldwide task force Jérôme Galon, Franck Pagès, Francesco M Marincola, Helen K Angell, Magdalena Thurin, Alessandro Lugli, Inti Zlobec, Anne Berger, Carlo Bifulco, Gerardo Botti, Fabiana Tatangelo, Cedrik M Britten, Sebastian Kreiter, Lotfi Chouchane, Paolo Delrio, Hartmann Arndt, Martin Asslaber, Michele Maio, Giuseppe V Masucci, Martin Mihm, Fernando Vidal-Vanaclocha, James P Allison, Sacha Gnjatic, Leif Hakansson, Christoph Huber, Harpreet Singh-Jasuja, Christian Ottensmeier, Heinz Zwierzina, Luigi Laghi, Fabio Grizzi et al. Journal of Translational Medicine 2012, 10:205 (3 October 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	11.	Research Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data Matthew Parker, Xiang Chen, Armita Bahrami, James Dalton, Michael Rusch, Gang Wu, John Easton, Nai-Kong Cheung, Michael Dyer, Elaine R Mardis, Richard K Wilson, Charles Mullighan, Richard Gilbertson, Suzanne J Baker, Gerard Zambetti, David W Ellison, James R Downing, Jinghui Zhang, Genome Biology 2012, 13:R113 (11 December 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A comprehensive analysis of telomere length changes in a large collection of pediatric tumors
	12.	Review Light chain (AL) amyloidosis: update on diagnosis and management Michael Rosenzweig, Heather Landau Journal of Hematology & Oncology 2011, 4:47 (18 November 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	13.	Review Vive la différence: biogenesis and evolution of microRNAs in plants and animals Michael J Axtell, Jakub O Westholm, Eric C Lai Genome Biology 2011, 12:221 (28 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The differences in biogenesis, function and evolution of plant and animal microRNAs contribute to, and are the result of, distinct evolutionary characteristics in the two kingdoms.
	14.	Debate Against quantiles: categorization of continuous variables in epidemiologic research, and its discontents Caroline Bennette, Andrew Vickers BMC Medical Research Methodology 2012, 12:21 (29 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Grouping continuous variables into quantiles is an intuitive concept in epidemiological research, but such an approach can be fundamentally problematic, and epidemiologists should consider alternatives.
	15.	Research Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2 Nikolaus Schultz, Dina R Marenstein, Dino A De Angelis, Wei-Qing Wang, Sven Nelander, Anders Jacobsen, Debora S Marks, Joan Massagué, Chris Sander Silence 2011, 2:3 (14 March 2011) Abstract \| Full text \| PDF \| PubMed
	16.	Research article Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer Marjan Berishaj, Sizhi Gao, Simi Ahmed, Kenneth Leslie, Hikmat Al-Ahmadie, William L Gerald, William Bornmann, Jacqueline F Bromberg Breast Cancer Research 2007, 9:R32 (25 May 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	17.	Editorial Preparing raw clinical data for publication: guidance for journal editors, authors, and peer reviewers Iain Hrynaszkiewicz, Melissa L Norton, Andrew J Vickers, Douglas G Altman Trials 2010, 11:9 (29 January 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	18.	Review Intensive care of the cancer patient: recent achievements and remaining challenges Elie Azoulay, Marcio Soares, Michael Darmon, Dominique Benoit, Stephen Pastores, Bekele Afessa Annals of Intensive Care 2011, 1:5 (23 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	19.	Review Antiangiogenic agents in the treatment of recurrent or newly diagnosed glioblastoma: Analysis of single-agent and combined modality approaches Kathryn Beal, Lauren E Abrey, Philip H Gutin Radiation Oncology 2011, 6:2 (7 January 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	20.	Research microRNA-146a inhibits G protein-coupled receptor-mediated activation of NF-κB by targeting CARD10 and COPS8 in gastric cancer Stephanie Crone, Anders Jacobsen, Birgitte Federspiel, Linda Bardram, Anders Krogh, Anders H Lund, Lennart Friis-Hansen Molecular Cancer 2012, 11:71 (20 September 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	21.	Study protocol Individual patient data meta-analysis of acupuncture for chronic pain: protocol of the Acupuncture Trialists' Collaboration Andrew J Vickers, Angel M Cronin, Alexandra C Maschino, George Lewith, Hugh Macpherson, Norbert Victor, Karen J Sherman, Claudia Witt, Klaus Linde, Trials 2010, 11:90 (28 September 2010) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	22.	Review Psychological adjustment of men with prostate cancer: a review of the literature Sidney Bloch, Anthony Love, Michelle Macvean, Gill Duchesne, Jeremy Couper, David Kissane BioPsychoSocial Medicine 2007, 1:2 (10 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23.	Research article Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 Anna Mulligan, Fergus J Couch, Daniel Barrowdale, Susan M Domchek, Diana Eccles, Heli Nevanlinna, Susan J Ramus, Mark Robson, Mark Sherman, Amanda B Spurdle, Barbara Wappenschmidt, Andrew Lee, Lesley McGuffog, Sue Healey, Olga M Sinilnikova, Ramunas Janavicius, Thomas vO Hansen, Finn C Nielsen, Bent Ejlertsen, Ana Osorio, Iván Muñoz-Repeto, Mercedes Durán, Javier Godino, Maroulio Pertesi, Javier Benítez, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Daniela Zaffaroni, Elisa Cattaneo et al. Breast Cancer Research 2011, 13:R110 (2 November 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	24.	Research article Vaccinia virus GLV-1h153 is a novel agent for detection and effective local control of positive surgical margins for breast cancer Sepideh Gholami, Chun-Hao Chen, Laurence J Belin, Emil Lou, Sho Fujisawa, Caroline Antonacci, Amanda Carew, Nanhai G Chen, Marina De Brot, Pat B Zanzonico, Aladar A Szalay, Yuman Fong Breast Cancer Research 2013, 15:R26 (18 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Oncolytic vaccinia virus, GLV1h-153, engineered to express the human sodium iodide symporter (hNIS) gene is useful in imaging cancers and can be used to identify and treat positive surgical margins of breast cancer in mice.
	25.	Review Heat shock protein 90 in neurodegenerative diseases Wenjie Luo, Weilin Sun, Tony Taldone, Anna Rodina, Gabriela Chiosis Molecular Neurodegeneration 2010, 5:24 (3 June 2010) Abstract \| Full text \| PDF \| PubMed