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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at Memorial Sloan Kettering Cancer Center

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	1.	Research article Parametric versus non-parametric statistics in the analysis of randomized trials with non-normally distributed data Andrew J Vickers BMC Medical Research Methodology 2005, 5:35 (3 November 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments \| Editor’s summary Analysis of simulated data reveals that ANCOVA should be the preferred method for analyzing randomized trials with pre-test and post-test measures and non-normally distributed data, but in cases with extreme skew, Mann-Whitney was preferred.
	2.	Methodology article A bright single-cell resolution live imaging reporter of Notch signaling in the mouse Sonja Nowotschin, Panagiotis Xenopoulos, Nadine Schrode, Anna-Katerina Hadjantonakis BMC Developmental Biology 2013, 13:15 (25 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Transgenic mice expressing a nuclear-localized fluorescent protein driven by responsive elements, taken from the CBF1 transcription factor, allow single-cell resolution of the Notch signaling pathway, with greater sensitivity and resolution than previous reporter lines.
	3.	Research The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1 Saad Z Usmani, Robert D Bona, Gabriela Chiosis, Zihai Li Journal of Hematology & Oncology 2010, 3:40 (26 October 2010) Abstract \| Full text \| PDF \| PubMed
	4.	Research Toxicity and outcomes of thoracic re-irradiation using stereotactic body radiation therapy (SBRT) Marsha Reyngold, Abraham J Wu, Amanda McLane, Zhigang Zhang, Meier Hsu, Nicholas F Stein, Ying Zhou, Alice Y Ho, Kenneth E Rosenzweig, Ellen D Yorke, Andreas Rimner Radiation Oncology 2013, 8:99 (25 April 2013) Abstract \| Full text \| PDF \| PubMed
	5.	Viewpoint Activating mutations and senescence secretome: new insights into HER2 activation, drug sensitivity and metastatic progression Swarnali Acharyya Breast Cancer Research 2013, 15:309 (23 April 2013) Abstract \| Full text \| PDF \| PubMed
	6.	Research article Cerebellum morphogenesis: the foliation pattern is orchestrated by multi-cellular anchoring centers Anamaria Sudarov, Alexandra L Joyner Neural Development 2007, 2:26 (3 December 2007) Abstract \| Full text \| PDF \| PubMed
	7.	Method Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites Doron Betel, Anjali Koppal, Phaedra Agius, Chris Sander, Christina Leslie Genome Biology 2010, 11:R90 (27 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary mirSVR is a method for miRNA target prediction that, unusually, takes into account non-canonical binding sequences and non-conserved sites
	8.	Research article The use of percentage change from baseline as an outcome in a controlled trial is statistically inefficient: a simulation study Andrew J Vickers BMC Medical Research Methodology 2001, 1:6 (28 June 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	9.	Research article Vaccinia virus GLV-1h153 is a novel agent for detection and effective local control of positive surgical margins for breast cancer Sepideh Gholami, Chun-Hao Chen, Laurence J Belin, Emil Lou, Sho Fujisawa, Caroline Antonacci, Amanda Carew, Nanhai G Chen, Marina De Brot, Pat B Zanzonico, Aladar A Szalay, Yuman Fong Breast Cancer Research 2013, 15:R26 (18 March 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Oncolytic vaccinia virus, GLV1h-153, engineered to express the human sodium iodide symporter (hNIS) gene is useful in imaging cancers and can be used to identify and treat positive surgical margins of breast cancer in mice.
	10.	Review Considerations in the development of circulating tumor cell technology for clinical use David R Parkinson, Nicholas Dracopoli, Brenda Petty, Carolyn Compton, Massimo Cristofanilli, Albert Deisseroth, Daniel F Hayes, Gordon Kapke, Prasanna Kumar, Jerry SH Lee, Minetta C Liu, Robert McCormack, Stanislaw Mikulski, Larry Nagahara, Klaus Pantel, Sonia Pearson-White, Elizabeth A Punnoose, Lori T Roadcap, Andrew E Schade, Howard I Scher, Caroline C Sigman, Gary J Kelloff Journal of Translational Medicine 2012, 10:138 (2 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	11.	Research article *Embryonic mammary signature subsets are activated in Brca1^-/-and basal-like breast cancers* Marketa Zvelebil, Erik Oliemuller, Qiong Gao, Olivia Wansbury, Alan Mackay, Howard Kendrick, Matthew J Smalley, Jorge S Reis-Filho, Beatrice A Howard Breast Cancer Research 2013, 15:R25 (18 March 2013) Abstract \| Full text \| PDF \| PubMed
	12.	Research MicroRNA targets in Drosophila Anton J Enright, Bino John, Ulrike Gaul, Thomas Tuschl, Chris Sander, Debora S Marks Genome Biology 2003, 5:R1 (12 December 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary A computational method for whole-genome prediction of microRNA target genes is presented. Application of this method to the Drosophila melanogaster, Drosophila pseudoobscura and Anopheles gambiae genomes identifies several hundred target genes potentially regulated by one or more known microRNAs.
	13.	Review Light chain (AL) amyloidosis: update on diagnosis and management Michael Rosenzweig, Heather Landau Journal of Hematology & Oncology 2011, 4:47 (18 November 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	14.	Methodology article An automated method for finding molecular complexes in large protein interaction networks Gary D Bader, Christopher WV Hogue BMC Bioinformatics 2003, 4:2 (13 January 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	15.	Review Cancer classification using the Immunoscore: a worldwide task force Jérôme Galon, Franck Pagès, Francesco M Marincola, Helen K Angell, Magdalena Thurin, Alessandro Lugli, Inti Zlobec, Anne Berger, Carlo Bifulco, Gerardo Botti, Fabiana Tatangelo, Cedrik M Britten, Sebastian Kreiter, Lotfi Chouchane, Paolo Delrio, Hartmann Arndt, Martin Asslaber, Michele Maio, Giuseppe V Masucci, Martin Mihm, Fernando Vidal-Vanaclocha, James P Allison, Sacha Gnjatic, Leif Hakansson, Christoph Huber, Harpreet Singh-Jasuja, Christian Ottensmeier, Heinz Zwierzina, Luigi Laghi, Fabio Grizzi et al. Journal of Translational Medicine 2012, 10:205 (3 October 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	16.	Commentary Defining the critical hurdles in cancer immunotherapy Bernard A Fox, Dolores J Schendel, Lisa H Butterfield, Steinar Aamdal, James P Allison, Paolo Ascierto, Michael B Atkins, Jirina Bartunkova, Lothar Bergmann, Neil Berinstein, Cristina C Bonorino, Ernest Borden, Jonathan L Bramson, Cedrik M Britten, Xuetao Cao, William E Carson, Alfred E Chang, Dainius Characiejus, A Raja Choudhury, George Coukos, Tanja de Gruijl, Robert O Dillman, Harry Dolstra, Glenn Dranoff, Lindy G Durrant, James H Finke, Jerome Galon, Jared A Gollob, Cécile Gouttefangeas, Fabio Grizzi et al. Journal of Translational Medicine 2011, 9:214 (14 December 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	17.	Review Complex roles of filamin-A mediated cytoskeleton network in cancer progression Jingyin Yue, Steven Huhn, Zhiyuan Shen Cell & Bioscience 2013, 3:7 (6 February 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	18.	Research article Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer Marjan Berishaj, Sizhi Gao, Simi Ahmed, Kenneth Leslie, Hikmat Al-Ahmadie, William L Gerald, William Bornmann, Jacqueline F Bromberg Breast Cancer Research 2007, 9:R32 (25 May 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	19.	Research article Molecular characterisation of cell line models for triple-negative breast cancers Anita Grigoriadis, Alan Mackay, Elodie Noel, Pei Wu, Rachel Natrajan, Jessica Frankum, Jorge S Reis-Filho, Andrew Tutt BMC Genomics 2012, 13:619 (14 November 2012) Abstract \| Full text \| PDF \| PubMed
	20.	Research Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity Alok K Tewari, Galip Yardimci, Yoichiro Shibata, Nathan C Sheffield, Lingyun Song, Barry S Taylor, Stoyan G Georgiev, Gerhard A Coetzee, Uwe Ohler, Terrence S Furey, Gregory E Crawford, Phillip G Febbo Genome Biology 2012, 13:R88 (3 October 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Androgen receptor binding to the genome occurs by multiple mechanisms and is associated with an increase in chromatin accessibility
	21.	Research Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2 Nikolaus Schultz, Dina R Marenstein, Dino A De Angelis, Wei-Qing Wang, Sven Nelander, Anders Jacobsen, Debora S Marks, Joan Massagué, Chris Sander Silence 2011, 2:3 (14 March 2011) Abstract \| Full text \| PDF \| PubMed
	22.	Research article Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 Anna Mulligan, Fergus J Couch, Daniel Barrowdale, Susan M Domchek, Diana Eccles, Heli Nevanlinna, Susan J Ramus, Mark Robson, Mark Sherman, Amanda B Spurdle, Barbara Wappenschmidt, Andrew Lee, Lesley McGuffog, Sue Healey, Olga M Sinilnikova, Ramunas Janavicius, Thomas vO Hansen, Finn C Nielsen, Bent Ejlertsen, Ana Osorio, Iván Muñoz-Repeto, Mercedes Durán, Javier Godino, Maroulio Pertesi, Javier Benítez, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Daniela Zaffaroni, Elisa Cattaneo et al. Breast Cancer Research 2011, 13:R110 (2 November 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23.	Proceedings An optimized algorithm for detecting and annotating regional differential methylation Sheng Li, Francine E Garrett-Bakelman, Altuna Akalin, Paul Zumbo, Ross Levine, Bik L To, Ian D Lewis, Anna L Brown, Richard J D'Andrea, Ari Melnick, Christopher E Mason BMC Bioinformatics 2013, 14(Suppl 5):S10 (10 April 2013) Abstract \| Full text \| PDF
	24.	Review Psychological adjustment of men with prostate cancer: a review of the literature Sidney Bloch, Anthony Love, Michelle Macvean, Gill Duchesne, Jeremy Couper, David Kissane BioPsychoSocial Medicine 2007, 1:2 (10 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	25.	Research Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data Matthew Parker, Xiang Chen, Armita Bahrami, James Dalton, Michael Rusch, Gang Wu, John Easton, Nai-Kong Cheung, Michael Dyer, Elaine R Mardis, Richard K Wilson, Charles Mullighan, Richard Gilbertson, Suzanne J Baker, Gerard Zambetti, David W Ellison, James R Downing, Jinghui Zhang, Genome Biology 2012, 13:R113 (11 December 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A comprehensive analysis of telomere length changes in a large collection of pediatric tumors