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176.

Research   Open Access

Prevalence of hypospadias in Italy according to severity, gestational age and birthweight: an epidemiological study

Paolo Ghirri, Rosa T Scaramuzzo, Silvano Bertelloni, Daniela Pardi, Amerigo Celandroni, Guido Cocchi, Roberto Danieli, Luisa De Santis, Maria C Di Stefano, Orietta Gerola, Mario Giuffrè, Giuseppe S Gragnani, Cinzia Magnani, Cristiano Meossi, Ilaria Merusi, Giuseppe Sabatino, Stefano Tumini, Giovanni Corsello, Antonio Boldrini Italian Journal of Pediatrics 2009, 35:18 (27 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

177.

Research   Open Access

Respiratory symptoms in children living near busy roads and their relationship to vehicular traffic: results of an Italian multicenter study (SIDRIA 2)

Enrica Migliore, Giovanna Berti, Claudia Galassi, Neil Pearce, Francesco Forastiere, Roberto Calabrese, Lucio Armenio, Annibale Biggeri, Luigi Bisanti, Massimiliano Bugiani, Ennio Cadum, Elisabetta Chellini, Valerio Dell'Orco, Gabriele Giannella, Piersante Sestini, Giuseppe Corbo, Riccardo Pistelli, Giovanni Viegi, Giovannino Ciccone, Environmental Health 2009, 8:27 (18 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

178.

Research   Open Access

Co-ordinated stage-dependent enhancement of Plasmodium falciparum antioxidant enzymes and heat shock protein expression in parasites growing in oxidatively stressed or G6PD-deficient red blood cells

Oscar Akide-Ndunge, Elisa Tambini, Giuliana Giribaldi, Paul J McMillan, Sylke Müller, Paolo Arese, Francesco Turrini Malaria Journal 2009, 8:113 (29 May 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A study of the expression of antioxidant enzymes and heat shock proteins of infected red blood cells under normal and oxidative conditions. Exogenous oxidative stress or cultivation of parasites in G6PD-deficient RBCs resulted in enhanced transcription and expression of all genes tested. The outstanding finding of this investigation is that the expression of Hsps was redox-responsive.

179.

Commentary   Free

Filtering out the noise: evaluating the impact of noise and sound reduction strategies on sleep quality for ICU patients

Karen J Bosma, V Marco Ranieri Critical Care 2009, 13:151 (29 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

180.

Research article   Open Access

AP-2α regulates migration of GN-11 neurons via a specific genetic programme involving the Axl receptor tyrosine kinase

Francesca Orso, Richard Jäger, Raffaele Calogero, Hubert Schorle, Piero Sismondi, Michele De Bortoli, Daniela Taverna BMC Biology 2009, 7:25 (22 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Neurons governing sexual behavior migrate to the hypothalamus after birth, and experiments on immortalised cells of this type suggest this is regulated by the transcription factor AP-2alpha via direct upregulation of the Adhesion Related Kinase gene.

181.

Study protocol   Open Access Highly Accessed

Rationale and design of an independent randomised controlled trial evaluating the effectiveness of aripiprazole or haloperidol in combination with clozapine for treatment-resistant schizophrenia

Michela Nosè, Simone Accordini, Paola Artioli, Francesco Barale, Corrado Barbui, Rossella Beneduce, Domenico Berardi, Gerardo Bertolazzi, Bruno Biancosino, Alfredo Bisogno, Raffaella Bivi, Filippo Bogetto, Marianna Boso, Alberto Bozzani, Piera Bucolo, Marcello Casale, Liliana Cascone, Luisa Ciammella, Alessia Cicolini, Gabriele Cipresso, Andrea Cipriani, Paola Colombo, Barbara Dal Santo, Michele De Francesco, Giorgio Di Lorenzo, Walter Di Munzio, Giuseppe Ducci, Arcadio Erlicher, Eleonora Esposito, Luigi Ferrannini et al. Trials 2009, 10:31 (15 May 2009)

Abstract | Full text | PDF | PubMed

182.

Review   Open Access Highly Accessed

Follicular fluid content and oocyte quality: from single biochemical markers to metabolomics

Alberto Revelli, Luisa Piane, Simona Casano, Emanuela Molinari, Marco Massobrio, Paolo Rinaudo Reproductive Biology and Endocrinology 2009, 7:40 (4 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

183.

Research   Open Access Highly Accessed

Subtelomeric FISH analysis in 76 patients with syndromic developmental delay/intellectual disability

Elga F Belligni, Elisa Biamino, Cristina Molinatto, Jole Messa, Mauro Pierluigi, Francesca Faravelli, Orsetta Zuffardi, Giovanni B Ferrero, Margherita Silengo Italian Journal of Pediatrics 2009, 35:9 (27 April 2009)

Abstract | Full text | PDF | PubMed

184.

Research   Open Access

Multiple primary tumours: incidence estimation in the presence of competing risks

Stefano Rosso, Lea Terracini, Fulvio Ricceri, Roberto Zanetti Population Health Metrics 2009, 7:5 (1 April 2009)

Abstract | Full text | PDF | PubMed

185.

Research article   Open Access

The isolation and mapping of a novel hydroxycinnamoyltransferase in the globe artichoke chlorogenic acid pathway

Cinzia Comino, Alain Hehn, Andrea Moglia, Barbara Menin, Frédéric Bourgaud, Sergio Lanteri, Ezio Portis BMC Plant Biology 2009, 9:30 (18 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

186.

Methodology   Open Access Highly Accessed

Methodological issues in estimating survival in patients with multiple primary cancers: an application to women with breast cancer as a first tumour

Stefano Rosso, Fulvio Ricceri, Lea Terracini, Roberto Zanetti Emerging Themes in Epidemiology 2009, 6:2 (27 February 2009)

Abstract | Full text | PDF | PubMed

187.

Research   Open Access

Isolation and characterisation of polychlorinated biphenyl (PCB) degrading fungi from a historically contaminated soil

Valeria Tigini, Valeria Prigione, Sara Di Toro, Fabio Fava, Giovanna C Varese Microbial Cell Factories 2009, 8:5 (12 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Mitosporic fungi Penicillium chrysogenum, Scedosporium apiospermum, Penicillium digitatum and Fusarium solani are the first strains found to degrade polychlorinated biphenyl (PCB), a widespread toxic pollutant.

188.

Research article   Open Access

Dissecting an alternative splicing analysis workflow for GeneChip® Exon 1.0 ST Affymetrix arrays

Cristina Della Beffa, Francesca Cordero, Raffaele A Calogero BMC Genomics 2008, 9:571 (28 November 2008)

Abstract | Full text | PDF | PubMed

189.

Research article   Open Access

Generation of potent neutralizing human monoclonal antibodies against cytomegalovirus infection from immune B cells

Ada Funaro, Giorgio Gribaudo, Anna Luganini, Erika Ortolan, Nicola Lo Buono, Elisa Vicenzi, Luca Cassetta, Santo Landolfo, Richard Buick, Luca Falciola, Marianne Murphy, Gianni Garotta, Fabio Malavasi BMC Biotechnology 2008, 8:85 (12 November 2008)

Abstract | Full text | PDF | PubMed

190.

Review   Open Access Highly Accessed

Redox mechanisms in hepatic chronic wound healing and fibrogenesis

Erica Novo, Maurizio Parola Fibrogenesis & Tissue Repair 2008, 1:5 (13 October 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

191.

Research article   Open Access

Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role

Luca Giliberto, Dawang Zhou, Richard Weldon, Elena Tamagno, Pasquale De Luca, Massimo Tabaton, Luciano D'Adamio Molecular Neurodegeneration 2008, 3:12 (2 September 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

192.

Research   Open Access Highly Accessed

Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: Role of IL-1beta and 15-HETE

Mauro Prato, Valentina Gallo, Giuliana Giribaldi, Paolo Arese Malaria Journal 2008, 7:157 (18 August 2008)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Haemozoin-containing trophozoites alters the functionality of human monocytes and macrophages, including an increase in TNF produced. This paper suggests a potential role for matrix metalloproteinases in this pathway.

193.

Research   Open Access

A novel hybrid aspirin-NO-releasing compound inhibits TNFalpha release from LPS-activated human monocytes and macrophages

Catriona M Turnbull, Paolo Marcarino, Tara A Sheldrake, Loretta Lazzarato, Clara Cena, Roberta Fruttero, Alberto Gasco, Sarah Fox, Ian L Megson, Adriano G Rossi Journal of Inflammation 2008, 5:12 (31 July 2008)

Abstract | Full text | PDF | PubMed

194.

Research article   Open Access

Gene-based microsatellite development for mapping and phylogeny studies in eggplant

Anikò Stàgel, Ezio Portis, Laura Toppino, Giuseppe Rotino, Sergio Lanteri BMC Genomics 2008, 9:357 (30 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

195.

Research article   Open Access Highly Accessed

Vinorelbine-based salvage therapy in HER2-positive metastatic breast cancer patients progressing during trastuzumab-containing regimens: a retrospective study

Filippo Montemurro, Stefania Redana, Franco Nolè, Michela Donadio, Maria Jacomuzzzi, Giorgio Valabrega, Giuseppe Viale, Anna Sapino, Massimo Aglietta BMC Cancer 2008, 8:209 (24 July 2008)

Abstract | Full text | PDF | PubMed

196.

Commentary   Open Access

Fractal parameters and vascular networks: facts & artifacts

Daniele Mancardi, Gianfranco Varetto, Enrico Bucci, Fabrizio Maniero, Caterina Guiot Theoretical Biology and Medical Modelling 2008, 5:12 (17 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

197.

Research article   Open Access

Genome-wide transcriptional changes induced by phagocytosis or growth on bacteria in Dictyostelium

Alessio Sillo, Gareth Bloomfield, Alessandra Balest, Alessandra Balbo, Barbara Pergolizzi, Barbara Peracino, Jason Skelton, Alasdair Ivens, Salvatore Bozzaro BMC Genomics 2008, 9:291 (17 June 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

198.

Methodology article   Open Access

Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes

Maria Martelli, Claudio Isella, Alessia Mira, Limin Fu, Daniela Cantarella, Enzo Medico BMC Genomics 2008, 9:254 (29 May 2008)

Abstract | Full text | PDF | PubMed

199.

Commentary   Open Access

Correlation between NK function and response to trastuzumab in metastatic breast cancer patients

Alessandra Beano, Elena Signorino, Andrea Evangelista, Davide Brusa, Marinella Mistrangelo, Maria Polimeni, Rosella Spadi, Michela Donadio, Libero Ciuffreda, Lina Matera Journal of Translational Medicine 2008, 6:25 (16 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

200.

Research   Open Access Highly Accessed

Diagnosis of ventilator-associated pneumonia: a systematic review of the literature

Alvaro Rea-Neto, Nazah Youssef, Fabio Tuche, Frank Brunkhorst, V Marco Ranieri, Konrad Reinhart, Yasser Sakr Critical Care 2008, 12:R56 (21 April 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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