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The mandate of NCBS is basic research in the frontier areas of biology. The research interests of the faculty are in the following areas. *Biochemistry, Biophysics and Bioinformatics *Genetics and Development *Cellular Organization and Signaling *Neurobiology

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	1.	Technical Note Structural attributes for the recognition of weak and anomalous regions in coiled-coils of myosins and other motor proteins Margaret S Sunitha, Anu G Nair, Amol Charya, Kamalakar Jadhav, Sami Mukhopadhyay, Ramanathan Sowdhamini BMC Research Notes 2012, 5:530 (25 September 2012) Abstract \| Full text \| PDF \| PubMed
	2.	Research article Re-visiting protein-centric two-tier classification of existing DNA-protein complexes Sony Malhotra, Ramanathan Sowdhamini BMC Bioinformatics 2012, 13:165 (16 July 2012) Abstract \| Full text \| PDF \| PubMed
	3.	Proceedings Relationship between amino acid properties and functional parameters in olfactory receptors and discrimination of mutants with enhanced specificity M Michael Gromiha, K Harini, R Sowdhamini, Kazuhiko Fukui BMC Bioinformatics 2012, 13(Suppl 7):S1 (8 May 2012) Abstract \| Full text \| PDF \| PubMed
	4.	Research Functional repertoire, molecular pathways and diseases associated with 3D domain swapping in the human proteome Khader Shameer, Ramanathan Sowdhamini Journal of Clinical Bioinformatics 2012, 2:8 (3 April 2012) Abstract \| Full text \| PDF \| PubMed
	5.	Research article Evolutionary traces decode molecular mechanism behind fast pace of myosin XI Divya P Syamaladevi, R Sowdhamini BMC Structural Biology 2011, 11:35 (26 September 2011) Abstract \| Full text \| PDF \| PubMed
	6.	Poster presentation Inferring ion channel densities from spike data Oliver Muthmann, Matthias H Hennig, Upinder S Bhalla BMC Neuroscience 2011, 12(Suppl 1):P12 (18 July 2011) Full text \| PDF
	7.	Research article Diverse and tissue-enriched small RNAs in the plant pathogenic fungus, Magnaporthe oryzae Cristiano C Nunes, Malali Gowda, Joshua Sailsbery, Minfeng Xue, Feng Chen, Douglas E Brown, YeonYee Oh, Thomas K Mitchell, Ralph A Dean BMC Genomics 2011, 12:288 (2 June 2011) Abstract \| Full text \| PDF \| PubMed
	8.	Research *Identification and analysis of a glutamatergic local interneuron lineage in the adult Drosophila* olfactory system** Abhijit Das, Albert Chiang, Sejal Davla, Rashi Priya, Heinrich Reichert, K VijayRaghavan, Veronica Rodrigues Neural Systems & Circuits 2011, 1:4 (26 January 2011) Abstract \| Full text \| PDF
	9.	Method A novel informatics concept for high-throughput shotgun lipidomics based on the molecular fragmentation query language Ronny Herzog, Dominik Schwudke, Kai Schuhmann, Julio L Sampaio, Stefan R Bornstein, Michael Schroeder, Andrej Shevchenko Genome Biology 2011, 12:R8 (19 January 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A novel method for lipid identification from all mass spectrometry platforms is presented within the software LipidXplorer
	10.	Software PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactomes Khader Shameer, Lalima L Madan, Shivamurthy Veeranna, Balasubramanian Gopal, Ramanathan Sowdhamini BMC Bioinformatics 2010, 11:473 (22 September 2010) Abstract \| Full text \| PDF \| PubMed
	11.	Short Report An evaluation of the PCR-RFLP technique to aid molecular-based monitoring of felids and canids in India Shomita Mukherjee, Ashalakshmi CN, Chandrima Home, Uma Ramakrishnan BMC Research Notes 2010, 3:159 (7 June 2010) Abstract \| Full text \| PDF \| PubMed
	12.	Short Report *Systematic search for putative new domain families in Mycoplasma gallisepticum* genome** Chilamakuri CS Reddy, Sane Rani, Bernard Offmann, R Sowdhamini BMC Research Notes 2010, 3:98 (12 April 2010) Abstract \| Full text \| PDF \| PubMed
	13.	Research HORI: a web server to compute Higher Order Residue Interactions in protein structures Pandurangan Sundaramurthy, Khader Shameer, Raashi Sreenivasan, Sunita Gakkhar, Ramanathan Sowdhamini BMC Bioinformatics 2010, 11(Suppl 1):S24 (18 January 2010) Abstract \| Full text \| PDF \| PubMed
	14.	Proceedings Evaluating epistatic interaction signals in complex traits using quantitative traits Odity Mukherjee, Krishna Sanapala, Padmanabhan Anbazhagana, Saurabh Ghosh BMC Proceedings 2009, 3(Suppl 7):S82 (15 December 2009) Abstract \| Full text \| PDF \| PubMed
	15.	Poster presentation Multiscale modeling and interoperability in MOOSE Niraj Dudani, Subhasis Ray, Siji George, Upinder S Bhalla BMC Neuroscience 2009, 10(Suppl 1):P54 (13 July 2009) Full text \| PDF
	16.	Research article Analysis on conservation of disulphide bonds and their structural features in homologous protein domain families Ratna R Thangudu, Malini Manoharan, N Srinivasan, Frédéric Cadet, R Sowdhamini, Bernard Offmann BMC Structural Biology 2008, 8:55 (26 December 2008) Abstract \| Full text \| PDF \| PubMed
	17.	Research article Drosophila olfactory local interneurons and projection neurons derive from a common neuroblast lineage specified by the empty spiracles gene Abhijit Das, Sonia Sen, Robert Lichtneckert, Ryuichi Okada, Kei Ito, Veronica Rodrigues, Heinrich Reichert Neural Development 2008, 3:33 (3 December 2008) Abstract \| Full text \| PDF \| PubMed
	18.	Research article Genome-wide survey of prokaryotic serine proteases: Analysis of distribution and domain architectures of five serine protease families in prokaryotes Lokesh P Tripathi, R Sowdhamini BMC Genomics 2008, 9:549 (19 November 2008) Abstract \| Full text \| PDF \| PubMed
	19.	Lecture presentation Modules in molecular memory Upinder S Bhalla BMC Neuroscience 2008, 9(Suppl 1):L2 (11 July 2008) Full text \| PDF
	20.	Research article CUSP: an algorithm to distinguish structurally conserved and unconserved regions in protein domain alignments and its application in the study of large length variations Sankaran Sandhya, Barah Pankaj, Madabosse Govind, Bernard Offmann, Narayanaswamy Srinivasan, Ramanathan Sowdhamini BMC Structural Biology 2008, 8:28 (31 May 2008) Abstract \| Full text \| PDF \| PubMed
	21.	Research article *Metamorphosis of an identified serotonergic neuron in the Drosophila* olfactory system** Bidisha Roy, Ajeet P Singh, Chetak Shetty, Varun Chaudhary, Annemarie North, Matthias Landgraf, K VijayRaghavan, Veronica Rodrigues Neural Development 2007, 2:20 (24 October 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	22.	Research article A machine learning approach for the identification of odorant binding proteins from sequence-derived properties Ganesan Pugalenthi, Ke Tang, PN Suganthan, G Archunan, R Sowdhamini BMC Bioinformatics 2007, 8:351 (19 September 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23.	Research article The N-terminus and alpha-5, alpha-6 helices of the pro-apoptotic protein Bax, modulate functional interactions with the anti-apoptotic protein Bcl-x_L Neha Parikh, Caroline Koshy, Vaigundan Dhayabaran, Lakshmi R Perumalsamy, R Sowdhamini, Apurva Sarin BMC Cell Biology 2007, 8:16 (23 May 2007) Abstract \| Full text \| PDF \| PubMed
	24.	Research article *Distinct types of glial cells populate the Drosophila* antenna** Anindya Sen, Chetak Shetty, Dhanisha Jhaveri, Veronica Rodrigues BMC Developmental Biology 2005, 5:25 (11 November 2005) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Drosophila antennae contain at least two distinct populations of glial cells, one of which originates in the brain and migrates via olfactory axons to the antenna.
	25.	Software Improvement of alignment accuracy utilizing sequentially conserved motifs Saikat Chakrabarti, Nitin Bhardwaj, Prem A Anand, Ramanathan Sowdhamini BMC Bioinformatics 2004, 5:167 (28 October 2004) Abstract \| Full text \| PDF \| PubMed