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1.

Software   Open Access

SeqSIMLA: a sequence and phenotype simulation tool for complex disease studies

Ren-Hua Chung, Chung-Chin Shih BMC Bioinformatics 2013, 14:199 (20 June 2013)

Abstract | Provisional PDF

2.

Research   Open Access Highly Accessed

Spending on vegetable and fruit consumption could reduce all-cause mortality among older adults

Yuan-Ting Lo, Yu-Hung Chang, Mark L Wahlqvist, Han-Bin Huang, Meei-Shyuan Lee Nutrition Journal 2012, 11:113 (19 December 2012)

Abstract | Full text | PDF | PubMed

3.

Research   Open Access Highly Accessed

Gaming control using a wearable and wireless EEG-based brain-computer interface device with novel dry foam-based sensors

Lun-De Liao, Chi-Yu Chen, I-Jan Wang, Sheng-Fu Chen, Shih-Yu Li, Bo-Wei Chen, Jyh-Yeong Chang, Chin-Teng Lin Journal of NeuroEngineering and Rehabilitation 2012, 9:5 (28 January 2012)

Abstract | Full text | PDF | PubMed

4.

Research article   Open Access Highly Accessed

Multiple-omic data analysis of Klebsiella pneumoniae MGH 78578 reveals its transcriptional architecture and regulatory features

Joo-Hyun Seo, Jay Sung-Joong Hong, Donghyuk Kim, Byung-Kwan Cho, Tzu-Wen Huang, Shih-Feng Tsai, Bernhard O Palsson, Pep Charusanti BMC Genomics 2012, 13:679 (29 November 2012)

Abstract | Full text | PDF | PubMed

5.

Research article   Open Access Highly Accessed

Chondroprotective effects and mechanisms of resveratrol in advanced glycation end products-stimulated chondrocytes

Feng-Cheng Liu, Li-Feng Hung, Wan-Lin Wu, Deh-Ming Chang, Chuan-Yueh Huang, Jenn-Haung Lai, Ling-Jun Ho Arthritis Research & Therapy 2010, 12:R167 (8 September 2010)

Abstract | Full text | PDF | PubMed

6.

Review   Open Access Highly Accessed

Roles of microRNAs in atherosclerosis and restenosis

Li-Jing Chen, Seh Lim, Yi-Ting Yeh, Sheng-Chieh Lien, Jeng-Jiann Chiu Journal of Biomedical Science 2012, 19:79 (29 August 2012)

Abstract | Full text | PDF | PubMed

7.

Research article   Open Access Highly Accessed

Emergence of extensively drug-resistant Acinetobacter baumannii complex over 10 years: Nationwide data from the Taiwan Surveillance of Antimicrobial Resistance (TSAR) program

Shu-Chen Kuo, Shan-Chwen Chang, Hui-Ying Wang, Jui-Fen Lai, Pei-Chen Chen, Yih-Ru Shiau, I-Wen Huang, Tsai-Ling Lauderdale, BMC Infectious Diseases 2012, 12:200 (28 August 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

8.

Research article   Open Access Highly Accessed

Risk factors for fatal candidemia caused by Candida albicans and non-albicans Candida species

Ming-Fang Cheng, Yun-Liang Yang, Tzy-Jyun Yao, Chin-Yu Lin, Jih-Shin Liu, Ran-Bin Tang, Kwok-Woon Yu, Yu-Hua Fan, Kai-Sheng Hsieh, Monto Ho, Hsiu-Jung Lo BMC Infectious Diseases 2005, 5:22 (7 April 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

9.

Review   Open Access Highly Accessed

DUSPs, to MAP kinases and beyond

Ching-Yu Huang, Tse-Hua Tan Cell & Bioscience 2012, 2:24 (9 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

10.

Research article   Open Access

Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker

Der-Yuan Chen, Huai-Chia Chuang, Joung-Liang Lan, Yi-Ming Chen, Wei-Ting Hung, Kuo-Lung Lai, Tse-Hua Tan BMC Medicine 2012, 10:84 (6 August 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Disease activity of adult-onset Still's disease, a rare form of inflammatory arthritis, can be measured by using levels of germinal center kinase-like kinase (GLK) as a biomarker for pathogenesis, which can be useful in establishing therapy efficacy.

11.

Research article   Open Access Highly Accessed

Gene expression profiling of breast cancer survivability by pooled cDNA microarray analysis using logistic regression, artificial neural networks and decision trees

Hsiu-Ling Chou, Chung-Tay Yao, Sui-Lun Su, Chia-Yi Lee, Kuang-Yu Hu, Harn-Jing Terng, Yun-Wen Shih, Yu-Tien Chang, Yu-Fen Lu, Chi-Wen Chang, Mark L Wahlqvist, Thomas Wetter, Chi-Ming Chu BMC Bioinformatics 2013, 14:100 (19 March 2013)

Abstract | Full text | PDF | PubMed

12.

Research   Open Access Highly Accessed

Enhancement of tolerance development to morphine in rats prenatally exposed to morphine, methadone, and buprenorphine

Yao-Chang Chiang, Tsai-Wei Hung, Cynthia Lee, Jia-Ying Yan, Ing-Kang Ho Journal of Biomedical Science 2010, 17:46 (7 June 2010)

Abstract | Full text | PDF | PubMed

13.

Research article   Open Access Highly Accessed

Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800,000 individuals

Meei-Shyuan Lee, Chih-Cheng Hsu, Mark L Wahlqvist, Hsin-Ni Tsai, Yu-Hung Chang, Yi-Chen Huang BMC Cancer 2011, 11:20 (18 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

14.

Research article   Open Access

Increased risk of affective disorders in type 2 diabetes is minimized by sulfonylurea and metformin combination: a population-based cohort study

Mark L Wahlqvist, Meei-Shyuan Lee, Shao-Yuan Chuang, Chih-Cheng Hsu, Hsin-Ni Tsai, Shu-Han Yu, Hsing-Yi Chang BMC Medicine 2012, 10:150 (29 November 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Type 2 diabetes patients treated with a combination of metformin and sulfonylurea have a lower risk of developing affective disorder than those not on these drugs, which may be relevant to reducing mental health problems in diabetes patients.

15.

Review   Open Access Highly Accessed

Androgens as therapy for androgen receptor-positive castration-resistant prostate cancer

Chih-Pin Chuu, John M Kokontis, Richard A Hiipakka, Junichi Fukuchi, Hui-Ping Lin, Ching-Yu Lin, Chiech Huo, Liang-Cheng Su Journal of Biomedical Science 2011, 18:63 (23 August 2011)

Abstract | Full text | PDF | PubMed

16.

Review   Open Access Highly Accessed

Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem cells

Pei-Min Chen, Men-Luh Yen, Ko-Jiunn Liu, Huey-Kang Sytwu, B-Linju Yen Journal of Biomedical Science 2011, 18:49 (18 July 2011)

Abstract | Full text | PDF | PubMed

17.

Primary research   Open Access Highly Accessed

A cell-permeable dominant-negative survivin protein induces apoptosis and sensitizes prostate cancer cells to TNF-α therapy

Chun Hei Antonio Cheung, Xueying Sun, Jagat R Kanwar, Ji-Zhong Bai, LiTing Cheng, Geoffrey W Krissansen Cancer Cell International 2010, 10:36 (1 October 2010)

Abstract | Full text | PDF | PubMed

18.

Research article   Open Access Highly Accessed

A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2

Ines Thiele, Daniel R Hyduke, Benjamin Steeb, Guy Fankam, Douglas K Allen, Susanna Bazzani, Pep Charusanti, Feng-Chi Chen, Ronan MT Fleming, Chao A Hsiung, Sigrid CJ De Keersmaecker, Yu-Chieh Liao, Kathleen Marchal, Monica L Mo, Emre Özdemir, Anu Raghunathan, Jennifer L Reed, Sook-Il Shin, Sara Sigurbjörnsdóttir, Jonas Steinmann, Suresh Sudarsan, Neil Swainston, Inge M Thijs, Karsten Zengler, Bernhard O Palsson, Joshua N Adkins, Dirk Bumann BMC Systems Biology 2011, 5:8 (18 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

19.

Research   Open Access

Effect of n-3 polyunsaturated fatty acid on gene expression of the critical enzymes involved in homocysteine metabolism

Tao Huang, Mark L Wahlqvist, Duo Li Nutrition Journal 2012, 11:6 (19 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

20.

Research   Open Access Highly Accessed

Dynamics of HBV cccDNA expression and transcription in different cell growth phase

Chin-Liew Chong, Mong-Liang Chen, Yi-Chieh Wu, Kuen-Nan Tsai, Chien-Chiao Huang, Cheng-po Hu, King-Song Jeng, Yu-Chi Chou, Chungming Chang Journal of Biomedical Science 2011, 18:96 (30 December 2011)

Abstract | Full text | PDF | PubMed

21.

Review   Open Access Highly Accessed

The nuclear envelopathies and human diseases

Ya-Hui Chi, Zi-Jie Chen, Kuan-Teh Jeang Journal of Biomedical Science 2009, 16:96 (22 October 2009)

Abstract | Full text | PDF | PubMed

22.

Research article   Open Access Highly Accessed

The reduction of tuberculosis risks by smoking cessation

Chi-Pang Wen, Ta-Chien Chan, Hui-Ting Chan, Min-Kuang Tsai, Ting-Yuang Cheng, Shan-Pou Tsai BMC Infectious Diseases 2010, 10:156 (7 June 2010)

Abstract | Full text | PDF | PubMed

23.

Research article   Open Access Highly Accessed

Joint predictability of health related quality of life and leisure time physical activity on mortality risk in people with diabetes

Chia-Lin Li, Hsing-Yi Chang, Chih-Cheng Hsu, Jui-fen Rachel Lu, Hsin-Ling Fang BMC Public Health 2013, 13:67 (24 January 2013)

Abstract | Full text | PDF | PubMed

24.

Research   Open Access

Biomonitoring of bisphenol A concentrations in maternal and umbilical cord blood in regard to birth outcomes and adipokine expression: a birth cohort study in Taiwan

Wei-Chun Chou, Jyh-Larng Chen, Chung-Fen Lin, Yi-Chun Chen, Feng-Cheng Shih, Chun-Yu Chuang Environmental Health 2011, 10:94 (3 November 2011)

Abstract | Full text | PDF | PubMed

25.

Research   Open Access Highly Accessed

Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity

Shin-Ru Shih, Tzu-Yun Chu, Gadarla Reddy, Sung-Nain Tseng, Hsiun-Ling Chen, Wen-Fang Tang, Ming-sian Wu, Jiann-Yih Yeh, Yu-Sheng Chao, John TA Hsu, Hsing-Pang Hsieh, Jim-Tong Horng Journal of Biomedical Science 2010, 17:13 (23 February 2010)

Abstract | Full text | PDF | PubMed

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