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51.

Study protocol   Open Access

Improving outcomes of preschool language delay in the community: protocol for the Language for Learning randomised controlled trial

Melissa Wake, Penny Levickis, Sherryn Tobin, Naomi Zens, James Law, Lisa Gold, Obioha C Ukoumunne, Sharon Goldfeld, Ha ND Le, Jemma Skeat, Sheena Reilly BMC Pediatrics 2012, 12:96 (9 July 2012)

Abstract | Full text | PDF | PubMed

52.

Poster presentation   Open Access

Management of shoulder dystocia: a re-audit

N Lynch, C Emmerson BMC Proceedings 2012, 6(Suppl 4):P11 (9 July 2012)

Full text | PDF

53.

Methodology   Open Access Highly Accessed

Developing clinical practice guidelines: reviewing, reporting, and publishing guidelines; updating guidelines; and the emerging issues of enhancing guideline implementability and accounting for comorbid conditions in guideline development

Paul Shekelle, Steven Woolf, Jeremy M Grimshaw, Holger J Schünemann, Martin P Eccles Implementation Science 2012, 7:62 (4 July 2012)

Abstract | Full text | PDF | PubMed

54.

Methodology   Open Access Highly Accessed

Developing clinical practice guidelines: types of evidence and outcomes; values and economics, synthesis, grading, and presentation and deriving recommendations

Steven Woolf, Holger J Schünemann, Martin P Eccles, Jeremy M Grimshaw, Paul Shekelle Implementation Science 2012, 7:61 (4 July 2012)

Abstract | Full text | PDF | PubMed

55.

Methodology   Open Access Highly Accessed

Developing clinical practice guidelines: target audiences, identifying topics for guidelines, guideline group composition and functioning and conflicts of interest

Martin P Eccles, Jeremy M Grimshaw, Paul Shekelle, Holger J Schünemann, Steven Woolf Implementation Science 2012, 7:60 (4 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

56.

Research article   Open Access

Aggregation, impaired degradation and immunization targeting of amyloid-beta dimers in Alzheimer’s disease: a stochastic modelling approach

Carole J Proctor, Ilse Pienaar, Joanna L Elson, Thomas BL Kirkwood Molecular Neurodegeneration 2012, 7:32 (2 July 2012)

Abstract | Full text | PDF | PubMed

57.

Review   Subscription

The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities

Jane WY Ng, Laura M Barrett, Andrew Wong, Diana Kuh, George Smith, Caroline L Relton Genome Biology 2012, 13:246 (29 June 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Longitudinal cohort studies provide an opportunity to study how changes in epigenetic patterns occur in response to diverse factors

58.

Research article   Open Access Highly Accessed

Small-area analyses of bone cancer diagnosed in Great Britain provide clues to aetiology

Richard J Q McNally, Karen Blakey, Roger C Parslow, Peter W James, Basilio Pozo, Charles Stiller, Tim J Vincent, Paul Norman, Patricia A McKinney, Michael F Murphy, Alan W Craft, Richard G Feltbower BMC Cancer 2012, 12:270 (27 June 2012)

Abstract | Full text | PDF | PubMed

59.

Software   Open Access

PREMIM and EMIM: tools for estimation of maternal, imprinting and interaction effects using multinomial modelling

Richard Howey, Heather J Cordell BMC Bioinformatics 2012, 13:149 (27 June 2012)

Abstract | Full text | PDF | PubMed

60.

Research article   Open Access

Predictors of drop-out in a multi-centre longitudinal study of participation and quality of life of children with cerebral palsy

Heather O Dickinson, Marion Rapp, Catherine Arnaud, Malin Carlsson, Allan F Colver, Jérôme Fauconnier, Alan Lyons, Marco Marcelli, Susan I Michelsen, Jackie Parkes, Kathryn Parkinson BMC Research Notes 2012, 5:300 (15 June 2012)

Abstract | Full text | PDF | PubMed

61.

Debate   Open Access Highly Accessed

Knowledge translation of research findings

Jeremy M Grimshaw, Martin P Eccles, John N Lavis, Sophie J Hill, Janet E Squires Implementation Science 2012, 7:50 (31 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

62.

Research   Open Access

Metabolic syndrome in type 2 diabetes: comparative prevalence according to two sets of diagnostic criteria in sub-Saharan Africans

Andre P Kengne, Serge N Limen, Eugene Sobngwi, Cathérine FT Djouogo, Christophe Nouedoui Diabetology & Metabolic Syndrome 2012, 4:22 (31 May 2012)

Abstract | Full text | PDF | PubMed

63.

Study protocol   Open Access

The Do-Well study: protocol for a randomised controlled trial, economic and qualitative process evaluations of domiciliary welfare rights advice for socio-economically disadvantaged older people recruited via primary health care

Catherine Haighton, Suzanne Moffatt, Denise Howel, Elaine McColl, Eugene Milne, Mark Deverill, Greg Rubin, Terry Aspray, Martin White BMC Public Health 2012, 12:382 (28 May 2012)

Abstract | Full text | PDF | PubMed

64.

Correspondence   Open Access

From theory to 'measurement' in complex interventions: Methodological lessons from the development of an e-health normalisation instrument

Tracy L Finch, Frances S Mair, Catherine O’Donnell, Elizabeth Murray, Carl R May BMC Medical Research Methodology 2012, 12:69 (17 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

65.

Research article   Open Access

MYOD-1 in normal colonic mucosa – role as a putative biomarker?

Ramesh P Arasaradnam, M Quraishi, Daniel Commane, John C Mathers, Mike Bradburn BMC Research Notes 2012, 5:240 (16 May 2012)

Abstract | Full text | PDF | PubMed

66.

Research   Open Access

Structure based hypothesis of a mitochondrial ribosome rescue mechanism

Martijn A Huynen, Isabel Duarte, Zofia M A Chrzanowska-Lightowlers, Sander B Nabuurs Biology Direct 2012, 7:14 (8 May 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Modeling the 3D structure of the human protein mtRF1 shows that it likely functions in recognizing and recycling stalled mitochondrial ribosomes.

67.

Research   Open Access

Altering gait by way of stimulation of the plantar surface of the foot: the immediate effect of wearing textured insoles in older fallers

Anna L Hatton, John Dixon, Keith Rome, Julia L Newton, Denis J Martin Journal of Foot and Ankle Research 2012, 5:11 (30 April 2012)

Abstract | Full text | PDF | PubMed

68.

Research article   Open Access

A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis

Lara Bossini-Castillo, Carmen P Simeon, Lorenzo Beretta, Jasper C Broen, Madelon C Vonk, Raquel Ríos-Fernández, Gerard Espinosa, Patricia Carreira, María T Camps, Maria J Castillo, Miguel A González-Gay, Emma Beltrán, María Carmen Freire, Javier Narváez, Carlos Tolosa, Torsten Witte, Alexander Kreuter, Annemie J Schuerwegh, Anna-Maria Hoffmann-Vold, Roger Hesselstrand, Claudio Lunardi, Jacob M van Laar, Meng Chee, Ariane Herrick, Bobby PC Koeleman, Christopher P Denton, Carmen Fonseca, Timothy RDJ Radstake, Javier Martin, Arthritis Research & Therapy 2012, 14:R85 (24 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

69.

Research   Open Access

What helps and hinders midwives in engaging with pregnant women about stopping smoking? A cross-sectional survey of perceived implementation difficulties among midwives in the North East of England

Jane Beenstock, Falko F Sniehotta, Martin White, Ruth Bell, Eugene MG Milne, Vera Araujo-Soares Implementation Science 2012, 7:36 (24 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

70.

Research   Open Access

Stream-based Hebbian eigenfilter for real-time neuronal spike discrimination

Bo Yu, Terrence Mak, Xiangyu Li, Leslie Smith, Yihe Sun, Chi-Sang Poon BioMedical Engineering OnLine 2012, 11:18 (10 April 2012)

Abstract | Full text | PDF | PubMed

71.

Software   Open Access Highly Accessed

The Transcription Factor Encyclopedia

Dimas Yusuf, Stefanie L Butland, Magdalena I Swanson, Eugene Bolotin, Amy Ticoll, Warren A Cheung, Xiao Cindy Zhang, Christopher TD Dickman, Debra L Fulton, Jonathan S Lim, Jake M Schnabl, Oscar HP Ramos, Mireille Vasseur-Cognet, Charles N de Leeuw, Elizabeth M Simpson, Gerhart U Ryffel, Eric W-F Lam, Ralf Kist, Miranda SC Wilson, Raquel Marco-Ferreres, Jan J Brosens, Leonardo L Beccari, Paola Bovolenta, Bérénice A Benayoun, Lara J Monteiro, Helma DC Schwenen, Lars Grontved, Elizabeth Wederell, Susanne Mandrup, Reiner A Veitia et al. Genome Biology 2012, 13:R24 (29 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

A high quality compendium of transcription factor data that allows researchers to add new data via a peer-review system

72.

Research   Open Access

Production and validation of a good manufacturing practice grade human fibroblast line for supporting human embryonic stem cell derivation and culture

Nilendran Prathalingam, Linda Ferguson, Lesley Young, Georg Lietz, Rachel Oldershaw, Lyn Healy, Albert Craig, Helen Lister, Rakesh Binaykia, Radhika Sheth, Alison Murdoch, Mary Herbert Stem Cell Research & Therapy 2012, 3:12 (28 March 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The human fibroblast line Ncl1Fed1A, produced in compliance with good manufacturing practice (GMP) standards, has been qualified for derivation and maintenance of human embryonic stem cells (hESCs).

73.

Poster presentation   Open Access

Does a physician-led Helicopter Emergency Medical Service (HEMS) favour its base hospital and interfere with agreed local trauma network ‘Trauma Decision Trees’?

O Maunsell, R Wen, A Weaver, D Lockey Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012, 20(Suppl 1):P1 (22 March 2012)

Full text | PDF

74.

Research article   Open Access

Induction of long-term B-cell depletion in refractory rheumatoid arthritis patients preferentially affects autoreactive more than protective humoral immunity

YK Onno Teng, Gillian Wheater, Vanessa E Hogan, Philip Stocks, EW Nivine Levarht, Tom WJ Huizinga, Rene EM Toes, Jacob M van Laar Arthritis Research & Therapy 2012, 14:R57 (12 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

75.

Research   Open Access

Particulate matter exposure during pregnancy is associated with birth weight, but not gestational age, 1962-1992: a cohort study

Mark S Pearce, Svetlana V Glinianaia, Rakesh Ghosh, Judith Rankin, Steven Rushton, Martin Charlton, Louise Parker, Tanja Pless-Mulloli Environmental Health 2012, 11:13 (9 March 2012)

Abstract | Full text | PDF | PubMed

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