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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at Morehouse School of Medicine

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1.

Research   Open Access Highly Accessed

Co-culture of Retinal and Endothelial Cells Results in the Modulation of Genes Critical to Retinal Neovascularization

Ravindra Kumar, Sandra Harris-Hooker, Ritesh Kumar, Gary Sanford Vascular Cell 2011, 3:27 (23 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

2.

Review   Open Access Highly Accessed

Genetic polymorphisms linked to susceptibility to malaria

Adel Driss, Jacqueline M Hibbert, Nana O Wilson, Shareen A Iqbal, Thomas V Adamkiewicz, Jonathan K Stiles Malaria Journal 2011, 10:271 (19 September 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This review describes and discusses human gene polymorphisms identified thus far that have been shown to be associated with susceptibility or resistance to P. falciparum malaria.

3.

Research   Open Access

Subunit and frequency-dependent inhibition of Acid Sensing Ion Channels by local anesthetic tetracaine

Tiandong Leng, Jun Lin, James E Cottrell, Zhi-Gang Xiong Molecular Pain 2013, 9:27 (10 June 2013)

Abstract | Provisional PDF | PubMed

4.

Research   Open Access

Evaluation of lymph node numbers for adequate staging of Stage II and III colon cancer

Chandrakumar Shanmugam, Robert B Hines, Nirag C Jhala, Venkat R Katkoori, Bin Zhang, James A Posey, Harvey L Bumpers, William E Grizzle, Isam E Eltoum, Gene P Siegal, Upender Manne Journal of Hematology & Oncology 2011, 4:25 (28 May 2011)

Abstract | Full text | PDF | PubMed

5.

Research article   Open Access

Gene expression patterns following unilateral traumatic brain injury reveals a local pro-inflammatory and remote anti-inflammatory response

Todd E White, Gregory D Ford, Monique C Surles-Zeigler, Alicia S Gates, Michelle C LaPlaca, Byron D Ford BMC Genomics 2013, 14:282 (25 April 2013)

Abstract | Full text | PDF | PubMed

6.

Research   Open Access

Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma

David J Tate, Derek J Vonderhaar, Yupanqui A Caldas, Toye Metoyer, John R Patterson, Diego H Aviles, Arnold H Zea Journal of Hematology & Oncology 2008, 1:14 (25 September 2008)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Inhibiting the enzyme arginase II produced by renal cell carcinomas may provide a novel therapeutic target by reducing L-arginine-induced tumor cell growth, and increasing the availability of L-arginine required for T-cell function.

7.

Research article   Open Access Highly Accessed

Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer

Ruben Rene Gonzalez, Amber Watters, Yanbo Xu, Udai P Singh, David R Mann, Bo R Rueda, Manuel L Penichet Breast Cancer Research 2009, 11:R36 (16 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Leptin-signaling inhibition has been shown to reduce tumour growth in a mouse model of breast cancer, supporting its potential use as a novel treatment for estrogen positive and negative breast cancer.

8.

Research article   Open Access

Gallotannin-rich Caesalpinia spinosa fraction decreases the primary tumor and factors associated with poor prognosis in a murine breast cancer model

Claudia Urueña, Juan Mancipe, John Hernandez, Diana Castañeda, Luis Pombo, Alejandra Gomez, Alexzander Asea, Susana Fiorentino BMC Complementary and Alternative Medicine 2013, 13:74 (3 April 2013)

Abstract | Full text | PDF | PubMed

9.

Research   Open Access

Vaticanol C, a resveratrol tetramer, activates PPARα and PPARβ/δ in vitro and in vivo

Tomoko Tsukamoto, Rieko Nakata, Emi Tamura, Yukiko Kosuge, Aya Kariya, Michiko Katsukawa, Satoshi Mishima, Tetsuro Ito, Munekazu Iinuma, Yukihiro Akao, Yoshinori Nozawa, Yuji Arai, Shobu Namura, Hiroyasu Inoue Nutrition & Metabolism 2010, 7:46 (27 May 2010)

Abstract | Full text | PDF | PubMed

10.

Research   Open Access Highly Accessed

Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India

Vidhan Jain, Henry B Armah, Jon E Tongren, Renée M Ned, Nana O Wilson, Sara Crawford, Pradeep K Joel, Mrigendra P Singh, Avinash C Nagpal, AP Dash, Venkatachalam Udhayakumar, Neeru Singh, Jonathan K Stiles Malaria Journal 2008, 7:83 (19 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

An extensive study on biomarkers of inflammation, apoptosis and angiogenesis in children and adults with cerebral malaria in India. A large amount of data is presented that sheds new light on potential mechanisms of CM pathogenesis.

11.

Research   Open Access Highly Accessed

Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children

Henry B Armah, Nana O Wilson, Bismark Y Sarfo, Michael D Powell, Vincent C Bond, Winston Anderson, Andrew A Adjei, Richard K Gyasi, Yao Tettey, Edwin K Wiredu, Jon Tongren, Venkatachalam Udhayakumar, Jonathan K Stiles Malaria Journal 2007, 6:147 (12 November 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The balance between specific cytokines and chemokines produced in response to infection is thought to play an important role in various forms of severe malaria. This study investigates the behaviour of 36 different biomarkers and identifies new clues for understanding pathophysiological events.

12.

Review   Open Access Highly Accessed

Chemoresistance in human ovarian cancer: the role of apoptotic regulators

Michael Fraser, Brendan Leung, Arezu Jahani-Asl, Xiaojuan Yan, Winston E Thompson, Benjamin K Tsang Reproductive Biology and Endocrinology 2003, 1:66 (7 October 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

13.

Research   Open Access Highly Accessed

PI3Kp110-, Src-, FAK-dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer cells

Christelle P El Haibi, Praveen K Sharma, Rajesh Singh, Paul R Johnson, Jill Suttles, Shailesh Singh, James W Lillard Molecular Cancer 2010, 9:85 (22 April 2010)

Abstract | Full text | PDF | PubMed

14.

Research article   Open Access

Interaction of sleep quality and psychosocial stress on obesity in African Americans: the Cardiovascular Health Epidemiology Study (CHES)

Aurelian Bidulescu, Rebecca Din-Dzietham, Dorothy L Coverson, Zhimin Chen, Yuan-Xiang Meng, Sarah G Buxbaum, Gary H Gibbons, Verna L Welch BMC Public Health 2010, 10:581 (28 September 2010)

Abstract | Full text | PDF | PubMed

15.

Research   Open Access

CCR9-CCL25 interactions promote cisplatin resistance in breast cancer cell through Akt activation in a PI3K-dependent and FAK-independent fashion

Crystal Johnson-Holiday, Rajesh Singh, Erica L Johnson, William E Grizzle, James W Lillard, Shailesh Singh World Journal of Surgical Oncology 2011, 9:46 (3 May 2011)

Abstract | Full text | PDF | PubMed

16.

Research   Open Access Highly Accessed

Degradation of insecticides used for indoor spraying in malaria control and possible solutions

Mthokozisi M Sibanda, Walter W Focke, Frederick JWJ Labuschagne, Lumbidzani Moyo, Nontete S Nhlapo, Arjun Maity, Herminio Muiambo, Pedro Massinga, Nico AS Crowther, Maureen Coetzee, Gordon WA Brindley Malaria Journal 2011, 10:307 (18 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

17.

Research   Open Access

Repeatability and measurement error in the assessment of choline and betaine dietary intake: the Atherosclerosis Risk in Communities (ARIC) Study

Aurelian Bidulescu, Lloyd E Chambless, Anna Siega-Riz, Steven H Zeisel, Gerardo Heiss Nutrition Journal 2009, 8:14 (20 February 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

Research   Open Access

Metformin therapy in a hyperandrogenic anovulatory mutant murine model with polycystic ovarian syndrome characteristics improves oocyte maturity during superovulation

Mary E Sabatini, Lankai Guo, Maureen P Lynch, Joseph O Doyle, HoJoon Lee, Bo R Rueda, Aaron K Styer Journal of Ovarian Research 2011, 4:8 (23 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

19.

Research   Open Access Highly Accessed

Plasmodium berghei ANKA infection increases Foxp3, IL-10 and IL-2 in CXCL-10 deficient C57BL/6 mice

Bismark Y Sarfo, Nana O Wilson, Vincent C Bond, Jonathan K Stiles Malaria Journal 2011, 10:69 (28 March 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The article continues to explore the underlying factors of dysregulation of the pro-inflammatory response implicated in cerebral malaria, using the mouse model.

20.

Research   Open Access Highly Accessed

CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-dependent and FAK-independent fashion

Erica L Johnson, Rajesh Singh, Crystal M Johnson-Holiday, William E Grizzle, Edward E Partridge, James W Lillard, Shailesh Singh Journal of Ovarian Research 2010, 3:15 (17 June 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

CCR9-CCL25 signalling promotes the survival of ovarian cancer cells and resistance to the chemotherepeutic cisplatin predominately through the PI3K/Akt pathwayand PI3K inhibition negates CCL25-mediated and CCR9-dependent cisplatin resistance.

21.

Research   Open Access Highly Accessed

Plasmodium yoelii 17XL infection up-regulates RANTES, CCR1, CCR3 and CCR5 expression, and induces ultrastructural changes in the cerebellum

Bismark Y Sarfo, Henry B Armah, Ikovwaiza Irune, Andrew A Adjei, Christine S Olver, Shailesh Singh, James W Lillard, Jonathan K Stiles Malaria Journal 2005, 4:63 (16 December 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This account of chemokine generation, and some of its effects, in a mouse malaria model introduces a little-investigated but important factor into the debate on the pathogenesis of cerebral malaria.

22.

Correspondence   Open Access Highly Accessed

Using GRADE methodology for the development of public health guidelines for the prevention and treatment of HIV and other STIs among men who have sex with men and transgender people

Elie A Akl, Caitlin Kennedy, Kelika Konda, Carlos F Caceres, Tara Horvath, George Ayala, Andrew Doupe, Antonio Gerbase, Charles Wiysonge, Eddy R Segura, Holger J Schünemann, Ying-Ru Lo BMC Public Health 2012, 12:386 (28 May 2012)

Abstract | Full text | PDF | PubMed

23.

Short report   Open Access

mtDNA sequence variants in subtypes of epithelial ovarian cancer stages in relation to ethnic and age difference

Felix O Aikhionbare, Sharifeh Mehrabi, Winston Thompson, Xuebiao Yao, William Grizzle, Edward Partridge Diagnostic Pathology 2008, 3:32 (28 July 2008)

Abstract | Full text | PDF | PubMed

24.

Research article   Open Access

A copy number variation in human NCF1 and its pseudogenes

Tiffany Brunson, Qingwei Wang, Isfahan Chambers, Qing Song BMC Genetics 2010, 11:13 (23 February 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

25.

Original investigation   Open Access

Does the association of the triglyceride to high-density lipoprotein cholesterol ratio with fasting serum insulin differ by race/ethnicity?

Chaoyang Li, Earl S Ford, Yuan-Xiang Meng, Ali H Mokdad, Gerald M Reaven Cardiovascular Diabetology 2008, 7:4 (28 February 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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