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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at University of Leicester

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1.

Research article   Open Access

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

Suzanne A Eccles, Eric O Aboagye, Simak Ali, Annie S Anderson, Jo Armes, Fedor Berditchevski, Jeremy P Blaydes, Keith Brennan, Nicola J Brown, Helen E Bryant, Nigel J Bundred, Joy M Burchell, Anna M Campbell, Jason S Carroll, Robert B Clarke, Charlotte E Coles, Gary JR Cook, Angela Cox, Nicola J Curtin, Lodewijk V Dekker, Isabel dos Santos Silva, Stephen W Duffy, Douglas F Easton, Diana M Eccles, Dylan R Edwards, Joanne Edwards, D Evans, Deborah F Fenlon, James M Flanagan, Claire Foster et al. Breast Cancer Research 2013, 15:R92 (1 October 2013)

Abstract | Full text | PDF |  Editor’s summary

Current knowledge 'gaps' in the understanding of breast cancer are examined, and research should focus on these to improve future clinical care.

2.

Research article   Open Access

The safety netting behaviour of first contact clinicians: a qualitative study

Caroline HD Jones, Sarah Neill, Monica Lakhanpaul, Damian Roland, Hayley Singlehurst-Mooney, Matthew Thompson BMC Family Practice 2013, 14:140 (25 September 2013)

Abstract | Full text | PDF | PubMed

3.

Protocol   Open Access

Understanding success and failure in multimorbidity: protocol for using realist synthesis to identify how social learning and workplace practices can be optimised

Sarah Yardley, Elizabeth Cottrell, Joanne Protheroe Systematic Reviews 2013, 2:87 (25 September 2013)

Abstract | Full text | PDF | PubMed

4.

Research   Open Access

Better together? a naturalistic qualitative study of inter-professional working in collaborative care for co-morbid depression and physical health problems

Sarah E Knowles, Carolyn Chew-Graham, Nia Coupe, Isabel Adeyemi, Chris Keyworth, Harish Thampy, Peter A Coventry Implementation Science 2013, 8:110 (20 September 2013)

Abstract | Full text | PDF | PubMed

5.

Methodology   Open Access

Issues in the incorporation of economic perspectives and evidence into Cochrane reviews

Ian Shemilt, David McDaid, Kevin Marsh, Catherine Henderson, Evelina Bertranou, Jacqueline Mallander, Mike Drummond, Miranda Mugford, Luke Vale, Systematic Reviews 2013, 2:83 (20 September 2013)

Abstract | Full text | PDF | PubMed

6.

Study protocol   Open Access

Vitamin D supplementation in older people (VDOP): Study protocol for a randomised controlled intervention trial with monthly oral dosing with 12,000 IU, 24,000 IU or 48,000 IU of vitamin D3

Inez Schoenmakers, Roger M Francis, Elaine McColl, Thomas Chadwick, Gail R Goldberg, Christine Harle, Alison Yarnall, Jennifer Wilkinson, Jennie Parker, Ann Prentice, Terence Aspray Trials 2013, 14:299 (17 September 2013)

Abstract | Full text | PDF | PubMed

7.

Research   Open Access

Innate immunity activation involved in unprotected porcine auto-transplant kidneys preserved by naked caspase-3 siRNA

Cheng Yang, Long Li, Yinjia Xue, Zitong Zhao, Tian Zhao, Yichen Jia, Ruiming Rong, Ming Xu, Michael L Nicholson, Tongyu Zhu, Bin Yang Journal of Translational Medicine 2013, 11:210 (13 September 2013)

Abstract | Full text | PDF | PubMed

8.

Poster presentation   Open Access

Identification of potent inhibitors of microtubule affinity regulating kinase for inhibition of tau hyperphosphorylation

Alison Levy, Michelle Newman, Janet Brownlees, Denise Harding, Joanne Osborne, Stephen Lewis, Kevin Gillen, Gareth Hall, Chido Mpamhanga, Andy Merritt, Debra Taylor, Ed Mclver Molecular Neurodegeneration 2013, 8(Suppl 1):P28 (13 September 2013)

Full text | PDF

9.

Meeting abstract   Open Access

Exploring older adults’ views about alcohol consumption: implications for brief interventions with older heavy drinkers

Graeme B Wilson, Eileen FS Kaner, Jonathan Ling, Ann Crosland, Karen McCabe, Catherine A Haighton Addiction Science & Clinical Practice 2013, 8(Suppl 1):A86 (4 September 2013)

Full text | PDF

10.

Research   Open Access

A potentiated startle study of uncertainty and contextual anxiety in adolescents diagnosed with autism spectrum disorder

Paul D Chamberlain, Jacqui Rodgers, Michael J Crowley, Sarah E White, Mark H Freeston, Mikle South Molecular Autism 2013, 4:31 (4 September 2013)

Abstract | Full text | PDF | PubMed

11.

Research article   Open Access

The effect of homocysteine-lowering with B-vitamins on osteoporotic fractures in patients with cerebrovascular disease: substudy of VITATOPS, a randomised placebo-controlled trial

John Gommans, Qilong Yi, John W Eikelboom, Graeme J Hankey, Christopher Chen, Helen Rodgers, BMC Geriatrics 2013, 13:88 (3 September 2013)

Abstract | Full text | PDF | PubMed

12.

Review   Open Access Highly Accessed

The clinical utility of bone marker measurements in osteoporosis

Gillian Wheater, Mohsen Elshahaly, Stephen P Tuck, Harish K Datta, Jacob M van Laar Journal of Translational Medicine 2013, 11:201 (29 August 2013)

Abstract | Full text | PDF | PubMed

13.

Research   Open Access

Secretion and assembly of functional mini-cellulosomes from synthetic chromosomal operons in Clostridium acetobutylicum ATCC 824

Katalin Kovács, Benjamin J Willson, Katrin Schwarz, John T Heap, Adam Jackson, David N Bolam, Klaus Winzer, Nigel P Minton Biotechnology for Biofuels 2013, 6:117 (20 August 2013)

Abstract | Full text | PDF | PubMed

14.

Original article   Open Access

Who contributes? A strategic approach to a European immigration policy

Giuseppe Russo, Luigi Senatore IZA Journal of Migration 2013, 2:16 (19 August 2013)

Abstract | Full text | PDF

15.

Study protocol   Open Access

Steroids or pentoxifylline for alcoholic hepatitis (STOPAH): study protocol for a randomised controlled trial

Ewan Forrest, Jane Mellor, Louise Stanton, Megan Bowers, Priscilla Ryder, Andrew Austin, Christopher Day, Dermot Gleeson, John O’Grady, Steven Masson, Anne McCune, David Patch, Paul Richardson, Paul Roderick, Stephen Ryder, Mark Wright, Mark Thursz Trials 2013, 14:262 (19 August 2013)

Abstract | Full text | PDF | PubMed

16.

Meeting abstract   Open Access

Histone deacetylase (HDAC) 1 and 2 are essential for normal T cell development and genomic stability in mice

Oliver M Dovey, George Vasilliou, Allan Bradley, Shaun M Cowley Clinical Epigenetics 2013, 5(Suppl 1):S11 (19 August 2013)

Full text | PDF

17.

Meeting abstract   Open Access

Regulation of proliferation and survival of B-lymphocytes by Ebf1 - implications in leukaemia

Ildikó Győry, Rudolf Grosschedl Clinical Epigenetics 2013, 5(Suppl 1):S4 (19 August 2013)

Full text | PDF

18.

Primary research   Open Access

Screening in silico predicted remotely acting NF1 gene regulatory elements for mutations in patients with neurofibromatosis type 1

Stephen E Hamby, Pablo Reviriego, David N Cooper, Meena Upadhyaya, Nadia Chuzhanova Human Genomics 2013, 7:18 (15 August 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Promise of a new approach to detect mutations underlying other inherited disorders that may be caused by mutations in remotely acting regulatory elements.

19.

Research article   Open Access

A qualitative study of cardiac rehabilitation patients’ perspectives on taking medicines: implications for the ‘medicines-resistance’ model of medicine-taking

Simon White, Paul Bissell, Claire Anderson BMC Health Services Research 2013, 13:302 (9 August 2013)

Abstract | Full text | PDF | PubMed

20.

Study protocol   Open Access

Study protocol for the randomised controlled trial: Antiglucocorticoid augmentation of anti-Depressants in Depression (The ADD Study)

R McAllister-Williams, Eleanor Smith, Ian M Anderson, Jane Barnes, Peter Gallagher, Heinz CR Grunze, Peter M Haddad, Allan O House, Tom Hughes, Adrian J Lloyd, Elaine MM McColl, Simon HS Pearce, Najma Siddiqi, Baxi Sinha, Chris Speed, I Steen, June Wainright, Stuart Watson, Fiona H Winter, I Ferrier BMC Psychiatry 2013, 13:205 (3 August 2013)

Abstract | Full text | PDF | PubMed

21.

Research article   Open Access

Musculoskeletal pain in older adults at the end-of-life: a systematic search and critical review of the literature with priorities for future research

Alison Lillie, Sue Read, Christian Mallen, Peter Croft, John McBeth BMC Palliative Care 2013, 12:27 (25 July 2013)

Abstract | Full text | PDF | PubMed

22.

Research article   Open Access Highly Accessed

How QOF is shaping primary care review consultations: a longitudinal qualitative study

Carolyn A Chew-Graham, Cheryl Hunter, Susanne Langer, Alexandra Stenhoff, Jessica Drinkwater, Elspeth A Guthrie, Peter Salmon BMC Family Practice 2013, 14:103 (21 July 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The UKs Quality and Outcomes Framework encourages review consultations with sufferers of long term conditions to focus more on “tick-box” biomedical criteria, at the expense of the patients perspective, suggesting further evolution of the QOF is required

23.

Research article   Open Access

Comparably high retention and low relapse rates in different subpopulations of bipolar patients in a German non-interventional study

Susanne Kraemer, Anette Minarzyk, Steffen Eppendorfer, Carsten Henneges, Hans-Peter Hundemer, Stefan Wilhelm, Heinz Grunze BMC Psychiatry 2013, 13:193 (17 July 2013)

Abstract | Full text | PDF | PubMed

24.

Research   Open Access

The impact of podoconiosis on quality of life in Northern Ethiopia

Elizabeth Mousley, Kebede Deribe, Abreham Tamiru, Gail Davey Health and Quality of Life Outcomes 2013, 11:122 (17 July 2013)

Abstract | Full text | PDF | PubMed

25.

Research article   Open Access

Designing a complex intervention for dementia case management in primary care

Amy Waugh, Allana Austin, Jill Manthorpe, Chris Fox, Barbara Stephens, Louise Robinson, Steve Iliffe BMC Family Practice 2013, 14:101 (17 July 2013)

Abstract | Full text | PDF | PubMed

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