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Member - Mathematisch-Naturwissenschaftliche Fakultät an der Universität zu Koeln

Mathematisch-Naturwissenschaftliche Fakultät an der Universität zu Koeln The Faculty of Mathematics and Natural Sciences at the University of Cologne encompasses more than 20 institutes and departments with research topics ranging from biology, chemistry and earth sciences to physics, mathematics/ informatics and science education. The faculty participates in 10 Collaborative Research Centres of the DFG, the Cluster of Excellence: Cellular Stress Responses in Aging-Associated Diseases, and several graduate schools.

http://www.uni-koeln.de/math-nat-fak/e_index.html


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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at Mathematisch-Naturwissenschaftliche Fakultät an der Universität zu Koeln

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151.

Research article   Open Access

A synaptic nidogen: Developmental regulation and role of nidogen-2 at the neuromuscular junction

Michael A Fox, Matthew SP Ho, Neil Smyth, Joshua R Sanes Neural Development 2008, 3:24 (25 September 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

152.

Oral presentation   Open Access

Astrocyte gp130-expression is critical for the control of Toxoplasma encephalitis

Katrin Drögemüller, Ulrike Helmuth, Anna Brunn, Monika Sakowicz-Burkiewicz, Dirk Reinhold, David H Gutmann, Werner Mueller, Martina Deckert, Dirk Schlüter BMC Proceedings 2008, 2(Suppl 1):S10 (23 September 2008)

Full text | PDF

153.

Research   Open Access

Corticosteroids reverse cytokine-induced block of survival and differentiation of oligodendrocyte progenitor cells from rats

Stefan A Mann, Beatrix Versmold, Romy Marx, Sabine Stahlhofen, Irmgard D Dietzel, Rolf Heumann, Richard Berger Journal of Neuroinflammation 2008, 5:39 (22 September 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

154.

Research article   Open Access

Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selection

Samuel Ojosnegros, Rubén Agudo, Macarena Sierra, Carlos Briones, Saleta Sierra, Claudia González- López, Esteban Domingo, Juan Cristina BMC Evolutionary Biology 2008, 8:207 (17 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

155.

Research article   Open Access

Chlamydial genes shed light on the evolution of photoautotrophic eukaryotes

Burkhard Becker, Kerstin Hoef-Emden, Michael Melkonian BMC Evolutionary Biology 2008, 8:203 (15 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

156.

Research   Open Access Highly Accessed

Inefficacy of different strategies to improve guideline awareness – 5-year follow-up of the hypertension evaluation project (HEP)

Jens Hagemeister, Christian A Schneider, Holger Diedrichs, Diana Mebus, Holger Pfaff, Gernot Wassmer, Hans W Höpp Trials 2008, 9:39 (25 June 2008)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Various training strategies were found to be ineffective in improving doctors’ awareness of hypertension treatment guidelines beyond spontaneous advancement of knowledge, in a five-year follow up of 8325 randomized physicians.

157.

Research article   Open Access

Gene transfer of Hodgkin cell lines via multivalent anti-CD30 scFv displaying bacteriophage

Yoon-Suk A Chung, Katja Sabel, Martin Krönke, Alexander Klimka BMC Molecular Biology 2008, 9:37 (16 April 2008)

Abstract | Full text | PDF | PubMed

158.

Research article   Open Access

Molecular and functional characterization of a Rho GDP dissociation inhibitor in the filamentous fungus Tuber borchii

Michele Menotta, Antonella Amicucci, Giorgio Basili, Emanuela Polidori, Vilberto Stocchi, Francisco Rivero BMC Microbiology 2008, 8:57 (9 April 2008)

Abstract | Full text | PDF | PubMed

159.

Research article   Open Access

Structural and functional diversification in the teleost S100 family of calcium-binding proteins

Andreas M Kraemer, Luis R Saraiva, Sigrun I Korsching BMC Evolutionary Biology 2008, 8:48 (14 February 2008)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The origin of the teleost S1000 subgroup of EF-Hand calcium-binding proteins predates the divergence of bony fish from cartilaginous fish and comprises 14 different subfamilies within teleosts.

160.

Methodology article   Open Access Highly Accessed

Simultaneous fitting of real-time PCR data with efficiency of amplification modeled as Gaussian function of target fluorescence

Anke Batsch, Andrea Noetel, Christian Fork, Anita Urban, Daliborka Lazic, Tina Lucas, Julia Pietsch, Andreas Lazar, Edgar Schömig, Dirk Gründemann BMC Bioinformatics 2008, 9:95 (12 February 2008)

Abstract | Full text | PDF | PubMed

161.

Research article   Open Access

Treatment delay of bone tumours, compilation of a sociodemographic risk profile: A retrospective study

Christoph Schnurr, Mathias Pippan, Hartmut Stuetzer, Karl S Delank, Joern WP Michael, Peer Eysel BMC Cancer 2008, 8:22 (23 January 2008)

Abstract | Full text | PDF | PubMed

162.

Research article   Open Access

Genomic, genetic and structural analysis of pyoverdine-mediated iron acquisition in the plant growth-promoting bacterium Pseudomonas fluorescens SBW25

Christina D Moon, Xue-Xian Zhang, Sandra Matthijs, Mathias Schäfer, Herbert Budzikiewicz, Paul B Rainey BMC Microbiology 2008, 8:7 (14 January 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

163.

Research   Open Access

Conservation and divergence of gene families encoding components of innate immune response systems in zebrafish

Cornelia Stein, Mario Caccamo, Gavin Laird, Maria Leptin Genome Biology 2007, 8:R251 (27 November 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Analysis of several fish genomes reveals components of the innate immune system and identifies orthologous relationships between gene families of fish and mammals.

164.

Research   Open Access

Transcriptomic and phenotypic analysis of murine embryonic stem cell derived BMP2+ lineage cells: an insight into mesodermal patterning

Michael Doss, Shuhua Chen, Johannes Winkler, Rita Hippler-Altenburg, Margareta Odenthal, Claudia Wickenhauser, Sridevi Balaraman, Herbert Schulz, Oliver Hummel, Norbert Hübner, Nandini Ghosh-Choudhury, Isaia Sotiriadou, Jürgen Hescheler, Agapios Sachinidis Genome Biology 2007, 8:R184 (4 September 2007)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Transcriptome analysis of BMP2+ cells in comparison to the undifferentiated BMP2 ES cells and the control population from 7-day old embryoid bodies led to the identification of 479 specifically upregulated and 193 downregulated transcripts.

165.

Research article   Open Access

Computational modeling of protein mutant stability: analysis and optimization of statistical potentials and structural features reveal insights into prediction model development

Vijaya Parthiban, M Michael Gromiha, Madenhalli Abhinandan, Dietmar Schomburg BMC Structural Biology 2007, 7:54 (16 August 2007)

Abstract | Full text | PDF | PubMed

166.

Methodology article   Open Access

Combination of scoring schemes for protein docking

Philipp Heuser, Dietmar Schomburg BMC Bioinformatics 2007, 8:279 (1 August 2007)

Abstract | Full text | PDF | PubMed

167.

Research article   Open Access

GxcDD, a putative RacGEF, is involved in Dictyostelium development

Subhanjan Mondal, Dhamodharan Neelamegan, Francisco Rivero, Angelika A Noegel BMC Cell Biology 2007, 8:23 (20 June 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

168.

Research article   Open Access

The ancestor of the Paulinella chromatophore obtained a carboxysomal operon by horizontal gene transfer from a Nitrococcus-like γ-proteobacterium

Birger Marin, Eva CM Nowack, Gernot Glöckner, Michael Melkonian BMC Evolutionary Biology 2007, 7:85 (5 June 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

169.

Research article   Open Access

Cross-study analysis of gene expression data for intermediate neuroblastoma identifies two biological subtypes

Patrick Warnat, André Oberthuer, Matthias Fischer, Frank Westermann, Roland Eils, Benedikt Brors BMC Cancer 2007, 7:89 (25 May 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

170.

Research article   Open Access

STATc is a key regulator of the transcriptional response to hyperosmotic shock

Jianbo Na, Budi Tunggal, Ludwig Eichinger BMC Genomics 2007, 8:123 (21 May 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The response of Dictyostelium to hyperosmotic shock involves the downregulation of metabolic machinery and upregulation of the stress response system including STATc, a key regulator of the transcriptional response to osmotic stress.

171.

Research article   Open Access

BRIP1 (BACH1) variants and familial breast cancer risk: a case-control study

Bernd Frank, Kari Hemminki, Alfons Meindl, Barbara Wappenschmidt, Christian Sutter, Marion Kiechle, Peter Bugert, Rita K Schmutzler, Claus R Bartram, Barbara Burwinkel BMC Cancer 2007, 7:83 (15 May 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

172.

Research article   Open Access

GrlJ, a Dictyostelium GABAB-like receptor with roles in post-aggregation development

Yogikala Prabhu, Rolf Müller, Christophe Anjard, Angelika A Noegel BMC Developmental Biology 2007, 7:44 (14 May 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

173.

Poster presentation   Open Access

Analysis of metabolome data by a maximum likelihood approach

Claudia Choi, Claudia Hundertmark, Bernhard Thielen, Beatrice Benkert, Richard Münch, Max Schobert, Dietmar Schomburg, Dieter Jahn, Frank Klawonn BMC Systems Biology 2007, 1(Suppl 1):P20 (8 May 2007)

Full text | PDF

174.

Research article   Open Access

Gain and loss of polyadenylation signals during evolution of green algae

Sabina Wodniok, Andreas Simon, Gernot Glöckner, Burkhard Becker BMC Evolutionary Biology 2007, 7:65 (18 April 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

There is a wide variation in polyadenylation signals among green algae ranging from a new UGUAA motif that arose in chlorophytes to a general lack of the A-rich motif that is typical of other eukaryotes.

175.

Research   Open Access

Global transcriptome analysis of murine embryonic stem cell-derived cardiomyocytes

Michael Doss, Johannes Winkler, Shuhua Chen, Rita Hippler-Altenburg, Isaia Sotiriadou, Marcel Halbach, Kurt Pfannkuche, Huamin Liang, Herbert Schulz, Oliver Hummel, Norbert Hübner, Ruth Rottscheidt, Jürgen Hescheler, Agapios Sachinidis Genome Biology 2007, 8:R56 (11 April 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Microarray analysis reveals that the specific pattern of gene expression in cardiomyocytes derived from embryonic stem cells reflects the biological, physiological and functional processes occurring in mature cardiomyocytes.

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