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Member - Mathematisch-Naturwissenschaftliche Fakultät an der Universität zu Koeln

The Faculty of Mathematics and Natural Sciences at the University of Cologne encompasses more than 20 institutes and departments with research topics ranging from biology, chemistry and earth sciences to physics, mathematics/ informatics and science education. The faculty participates in 10 Collaborative Research Centres of the DFG, the Cluster of Excellence: Cellular Stress Responses in Aging-Associated Diseases, and several graduate schools.

http://www.uni-koeln.de/math-nat-fak/e_index.html

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Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at Mathematisch-Naturwissenschaftliche Fakultät an der Universität zu Koeln

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	1.	Commentary Predicting the evolution of antibiotic resistance Martijn F Schenk, J Arjan GM de Visser BMC Biology 2013, 11:14 (22 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Commenting on research in BMC Evolutionary Biology, Arjan de Visser and Martijn Schenk discuss how two genetic properties, pleiotropy and epistasis, might help us to predict the evolution of antibiotic resistance.
	2.	Protocol Individual patient data meta-analysis for the clinical assessment of coronary computed tomography angiography: protocol of the Collaborative Meta-Analysis of Cardiac CT (CoMe-CCT) Georg M Schuetz, Peter Schlattmann, Stephan Achenbach, Matthew Budoff, Mario J Garcia, Robert Roehle, Gianluca Pontone, Willem Bob Meijboom, Daniele Andreini, Hatem Alkadhi, Lily Honoris, Nuno Bettencourt, Jörg Hausleiter, Sebastian Leschka, Bernhard L Gerber, Matthijs FL Meijs, Abbas Arjmand Shabestari, Akira Sato, Elke Zimmermann, Uwe J Schoepf, Axel Diederichsen, David A Halon, Vladimir Mendoza-Rodriguez, Ashraf Hamdan, Bjarne L Nørgaard, Harald Brodoefel, Kristian A Øvrehus, Shona MM Jenkins, Bjørn A Halvorsen, Johannes Rixe et al. Systematic Reviews 2013, 2:13 (15 February 2013) Abstract \| Full text \| PDF \| PubMed
	3.	Research article Deficiency in four and one half LIM domain protein 2 (FHL2) aggravates liver fibrosis in mice Sebastian Huss, Christian Stellmacher, Diane Goltz, Inna Khlistunova, Alexander C Adam, Jonel Trebicka, Jutta Kirfel, Reinhard Büttner, Ralf Weiskirchen BMC Gastroenterology 2013, 13:8 (14 January 2013) Abstract \| Full text \| PDF \| PubMed
	4.	Research article Effects of spermine NONOate and ATP on protein aggregation: light scattering evidences Rasha Bassam, Ilya Digel, Juergen Hescheler, Ayseguel Temiz Artmann, Gerhard M Artmann BMC Biophysics 2013, 6:1 (4 January 2013) Abstract \| Full text \| PDF \| PubMed
	5.	Database OPTIMAS-DW: A comprehensive transcriptomics, metabolomics, ionomics, proteomics and phenomics data resource for maize Christian Colmsee, Martin Mascher, Tobias Czauderna, Anja Hartmann, Urte Schlüter, Nina Zellerhoff, Jessica Schmitz, Andrea Bräutigam, Thea R Pick, Philipp Alter, Manfred Gahrtz, Sandra Witt, Alisdair R Fernie, Frederik Börnke, Holger Fahnenstich, Marcel Bucher, Thomas Dresselhaus, Andreas PM Weber, Falk Schreiber, Uwe Scholz, Uwe Sonnewald BMC Plant Biology 2012, 12:245 (29 December 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The OPTIMAS Data Warehouse (OPTIMAS-DW) is a comprehensive collection of data for maize, integrating data from different domains such as transcriptomics, metabolomics, ionomics, proteomics and phenomics, and particularly supports systems biological research
	6.	Research article Mucin-1 and its relation to grade, stage and survival in ovarian carcinoma patients Verena Engelstaedter, Sabine Heublein, Anamur Lan Schumacher, Miriam Lenhard, Helen Engelstaedter, Ulrich Andergassen, Margit Guenthner-Biller, Christina Kuhn, Brigitte Rack, Markus Kupka, Doris Mayr, Udo Jeschke BMC Cancer 2012, 12:600 (15 December 2012) Abstract \| Full text \| PDF \| PubMed
	7.	Software GraphAlignment: Bayesian pairwise alignment of biological networks Michal Kolář, Jörn Meier, Ville Mustonen, Michael Lässig, Johannes Berg BMC Systems Biology 2012, 6:144 (21 November 2012) Abstract \| Full text \| PDF \| PubMed
	8.	Poster presentation Regulation of sepsis-induced IFNγ upon natural killer cell or natural killer T cell depletion in vivo E Christaki, E Diza, EJ Giamarellos-Bourboulis, N Papadopoulou, A Pistiki, D Droggiti, A Machova, M Georgitsi, D Lambrelli, G Karkavelas, A Iliadis, N Malisiovas, P Nikolaidis, SM Opal Critical Care 2012, 16(Suppl 3):P46 (14 November 2012) Full text \| PDF
	9.	Research article Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis Stefan Taudien, Gabor Gäbel, Oliver Kuss, Marco Groth, Robert Grützmann, Klaus Huse, Alexander Kluttig, Andreas Wolf, Michael Nothnagel, Philip Rosenstiel, Karin Halina Greiser, Karl Werdan, Michael Krawczak, Christian Pilarsky, Matthias Platzer BMC Research Notes 2012, 5:629 (13 November 2012) Abstract \| Full text \| PDF \| PubMed
	10.	Poster presentation Development of dynamical weather-disease models to project and forecast malaria in Africa Volker Ermert, Andreas H Fink, Andrew P Morse, Anne E Jones, Heiko Paeth, Francesca Di Giuseppe, Adrian M Tompkins Malaria Journal 2012, 11(Suppl 1):P133 (9 November 2012) Full text \| PDF
	11.	Case report Frank-ter Haar syndrome associated with sagittal craniosynostosis and raised intracranial pressure Charlotte L Bendon, Aimée L Fenwick, Jane A Hurst, Gudrun Nürnberg, Peter Nürnberg, Steven A Wall, Andrew OM Wilkie, David Johnson BMC Medical Genetics 2012, 13:104 (9 November 2012) Abstract \| Full text \| PDF \| PubMed
	12.	Research article Analysis of posaconazole as oral antifungal prophylaxis in pediatric patients under 12 years of age following allogeneic stem cell transplantation Michaela Döring, Carsten Müller, Pascal-David Johann, Annika Erbacher, Astrid Kimmig, Carl-Philipp Schwarze, Peter Lang, Rupert Handgretinger, Ingo Müller BMC Infectious Diseases 2012, 12:263 (19 October 2012) Abstract \| Full text \| PDF \| PubMed
	13.	Research article Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases Stefanie Huhn, Melanie Bevier, Anja Rudolph, Barbara Pardini, Alessio Naccarati, Rebecca Hein, Michael Hoffmeister, Ludmila Vodickova, Jan Novotny, Hermann Brenner, Jenny Chang-Claude, Kari Hemminki, Pavel Vodicka, Asta Försti BMC Medical Genetics 2012, 13:94 (5 October 2012) Abstract \| Full text \| PDF \| PubMed
	14.	Oral presentation MutaScope: a high-sensitivity variant caller dedicated to high-throughput PCR amplicons sequencing Shawn Yost, Hakan Alakus, Hiroko Matsui, Kristen Jepsen, Richard Schwab, Kelly Frazer, Olivier Harismendy BMC Proceedings 2012, 6(Suppl 6):O22 (1 October 2012) Full text \| PDF
	15.	Research article Ubiquitin initiates sorting of Golgi and plasma membrane proteins into the vacuolar degradation pathway David Scheuring, Fabian Künzl, Corrado Viotti, Melody San Wan Yan, Liwen Jiang, Swen Schellmann, David G Robinson, Peter Pimpl BMC Plant Biology 2012, 12:164 (12 September 2012) Abstract \| Full text \| PDF \| PubMed
	16.	Research Corticotropin-releasing hormone stimulates expression of leptin, 11beta-HSD2 and syncytin-1 in primary human trophoblasts Fabian B Fahlbusch, Matthias Ruebner, Gudrun Volkert, Ramona Offergeld, Andrea Hartner, Carlos Menendez-Castro, Reiner Strick, Manfred Rauh, Wolfgang Rascher, Jörg Dötsch Reproductive Biology and Endocrinology 2012, 10:80 (12 September 2012) Abstract \| Full text \| PDF \| PubMed
	17.	Research *Targeted next-generation sequencing identifies a homozygous nonsense mutation in ABHD12, the gene underlying PHARC, in a family clinically diagnosed with Usher syndrome type 3* Tobias Eisenberger, Rima Slim, Ahmad Mansour, Markus Nauck, Gudrun Nürnberg, Peter Nürnberg, Christian Decker, Claudia Dafinger, Inga Ebermann, Carsten Bergmann, Hanno Bolz Orphanet Journal of Rare Diseases 2012, 7:59 (2 September 2012) Abstract \| Full text \| PDF \| PubMed
	18.	Research article Effects of spermine NONOate and ATP on the thermal stability of hemoglobin Rasha Bassam, Juergen Hescheler, Ayseguel Temiz-Artmann, Gerhard M Artmann, Ilya Digel BMC Biophysics 2012, 5:16 (28 August 2012) Abstract \| Full text \| PDF \| PubMed
	19.	Research article Elevated expression of LSD1 (Lysine-specific demethylase 1) during tumour progression from pre-invasive to invasive ductal carcinoma of the breast Nuran Serce, Annette Gnatzy, Susanne Steiner, Henning Lorenzen, Jutta Kirfel, Reinhard Buettner BMC Clinical Pathology 2012, 12:13 (24 August 2012) Abstract \| Full text \| PDF \| PubMed
	20.	Review Human Immunodeficiency Virus gag and protease: partners in resistance Axel Fun, Annemarie MJ Wensing, Jens Verheyen, Monique Nijhuis Retrovirology 2012, 9:63 (6 August 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary This review addresses in detail all mutations in Gag that are selected under PI pressure. It evaluates how polymorphisms and mutations in Gag affect PI therapy, an aspect of PI resistance that is currently not included in standard genotypic PI resistance testing.
	21.	Research article *Therapeutic concentrations of antibiotics inhibit Shiga toxin release from enterohemorrhagic E. coli* O104:H4 from the 2011 German outbreak** Diana Corogeanu, Ruben Willmes, Martina Wolke, Georg Plum, Olaf Utermöhlen, Martin Krönke BMC Microbiology 2012, 12:160 (1 August 2012) Abstract \| Full text \| PDF \| PubMed
	22.	Methodology A note on the graphical presentation of prediction intervals in random-effects meta-analyses Charlotte Guddat, Ulrich Grouven, Ralf Bender, Guido Skipka Systematic Reviews 2012, 1:34 (28 July 2012) Abstract \| Full text \| PDF \| PubMed
	23.	Research An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data Katarzyna Bozek, Manon Eckhardt, Saleta Sierra, Maria Anders, Rolf Kaiser, Hans-Georg Kräusslich, Barbara Müller, Thomas Lengauer Retrovirology 2012, 9:60 (25 July 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary This study developed a multivariate phenotype descriptor, termed phenotype vector, which facilitates a more detailed characterization of HIV entry phenotypes than currently used binary tropism classifications. For some of the tested virus variants, the multivariant phenotype vector revealed substantial divergences from existing tropism predictions.
	24.	Poster presentation Analysis of excitatory and inhibitory interactions at high temporal resolution in core circuits of the respiratory CPG Yaroslav I Molkov, Anke Borgmann, Ruli Zhang, Ilya A Rybak, Jeffrey C Smith BMC Neuroscience 2012, 13(Suppl 1):P39 (16 July 2012) Full text \| PDF
	25.	Research Linking the Tinnitus Questionnaire and the subjective Clinical Global Impression: Which differences are clinically important? Ilya Adamchic, Peter Tass, Berthold Langguth, Christian Hauptmann, Michael Koller, Martin Schecklmann, Florian Zeman, Michael Landgrebe Health and Quality of Life Outcomes 2012, 10:79 (10 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central