1.
Toward knowledge support for analysis and interpretation of complex traits
Nigel
Collier,
Anika
Oellrich,
Tudor
Groza
Genome Biology 2013, 14 :214 (30 September 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Nigel Collier reviews how algorithmic advances are set to enhance the description of complex traits through high-throughput phenotype analysis
2.
Benchmarking of protein descriptor sets in proteochemometric modeling (part 2): modeling performance of 13 amino acid descriptor sets
Gerard
JP
van Westen,
Remco
F
Swier,
Isidro
Cortes-Ciriano,
Jörg
K
Wegner,
John
P
Overington,
Adriaan
P
IJzerman,
Herman
WT
van Vlijmen,
Andreas
Bender
Journal of Cheminformatics 2013, 5 :42 (24 September 2013)
Abstract | Full text | PDF | PubMed
3.
Benchmarking of protein descriptor sets in proteochemometric modeling (part 1): comparative study of 13 amino acid descriptor sets
Gerard
JP
van Westen,
Remco
F
Swier,
Jörg
K
Wegner,
Adriaan
P
IJzerman,
Herman
WT
van Vlijmen,
Andreas
Bender
Journal of Cheminformatics 2013, 5 :41 (23 September 2013)
Abstract | Full text | PDF | PubMed
4.
A combination of improved differential and global RNA-seq reveals pervasive transcription initiation and events in all stages of the life-cycle of functional RNAs in Propionibacterium acnes , a major contributor to wide-spread human disease
Yu-fei
Lin,
David
A,
Shuang
Guan,
Lira
Mamanova,
Kenneth
J
McDowall
BMC Genomics 2013, 14 :620 (14 September 2013)
Abstract | Full text | PDF | PubMed
5.
Two Pfam protein families characterized by a crystal structure of protein lpg2210 from Legionella pneumophila
Penelope
Coggill,
Ruth
Y
Eberhardt,
Robert
D
Finn,
Yuanyuan
Chang,
Lukasz
Jaroszewski,
Adam
Godzik,
Debanu
Das,
Qingping
Xu,
Herbert
L
Axelrod,
L
Aravind,
Alexey
G
Murzin,
Alex
Bateman
BMC Bioinformatics 2013, 14 :265 (3 September 2013)
Abstract | Full text | PDF | PubMed
6.
Ontology based molecular signatures for immune cell types via gene expression analysis
Terrence
F
Meehan,
Nicole
A
Vasilevsky,
Christopher
J
Mungall,
David
S
Dougall,
Melissa
A
Haendel,
Judith
A
Blake,
Alexander
D
Diehl
BMC Bioinformatics 2013, 14 :263 (30 August 2013)
Abstract | Full text | PDF | PubMed
7.
LeView: automatic and interactive generation of 2D diagrams for biomacromolecule/ligand interactions
Ségolène
Caboche
Journal of Cheminformatics 2013, 5 :40 (29 August 2013)
Abstract | Full text | PDF | PubMed
8.
The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery
Roz
Laing,
Taisei
Kikuchi,
Axel
Martinelli,
Isheng
J
Tsai,
Robin
N
Beech,
Elizabeth
Redman,
Nancy
Holroyd,
David
J
Bartley,
Helen
Beasley,
Collette
Britton,
David
Curran,
Eileen
Devaney,
Aude
Gilabert,
Martin
Hunt,
Frank
Jackson,
Stephanie
Johnston,
Ivan
Kryukov,
Keyu
Li,
Alison
A
Morrison,
Adam
J
Reid,
Neil
Sargison,
Gary
Saunders,
James
D
Wasmuth,
Adrian
Wolstenholme,
Matthew
Berriman,
John
S
Gilleard,
James
A
Cotton
Genome Biology 2013, 14 :R88 (28 August 2013)
Abstract | Provisional PDF
| PubMed
|
Editor’s summary
The genome and transcriptome of Haemonchus contortus, a nematode parasite of sheep, provides insights into antihelminthic resistance
9.
KNIME-CDK: Workflow-driven cheminformatics
Stephan
Beisken,
Thorsten
Meinl,
Bernd
Wiswedel,
Luis
F
de Figueiredo,
Michael
Berthold,
Christoph
Steinbeck
BMC Bioinformatics 2013, 14 :257 (22 August 2013)
Abstract | Full text | PDF
10.
Histone deacetylase (HDAC) 1 and 2 are essential for normal T cell development and genomic stability in mice
Oliver
M
Dovey,
George
Vasilliou,
Allan
Bradley,
Shaun
M
Cowley
Clinical Epigenetics 2013, 5 (Suppl 1):S11 (19 August 2013)
Full text | PDF
11.
Transcription of a protein-coding gene on B chromosomes of the Siberian roe deer (Capreolus pygargus )
Vladimir
A
Trifonov,
Polina
V
Dementyeva,
Denis
M
Larkin,
Patricia
CM
O’Brien,
Polina
L
Perelman,
Fengtang
Yang,
Malcolm
A
Ferguson-Smith,
Alexander
S
Graphodatsky
BMC Biology 2013, 11 :90 (6 August 2013)
Abstract | Full text | PDF | PubMed
12.
So, you want to sequence a genome...
Derek
L
Stemple
Genome Biology 2013, 14 :128 (30 July 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Derek Stemple discusses lessons learned from the zebrafish genome project
13.
Dovetailing biology and chemistry: integrating the Gene Ontology with the ChEBI chemical ontology
David
P
Hill,
Nico
Adams,
Mike
Bada,
Colin
Batchelor,
Tanya
Z
Berardini,
Heiko
Dietze,
Harold
J
Drabkin,
Marcus
Ennis,
Rebecca
E
Foulger,
Midori
A
Harris,
Janna
Hastings,
Namrata
S
Kale,
Paula
de Matos,
Christopher
J
Mungall,
Gareth
Owen,
Paola
Roncaglia,
Christoph
Steinbeck,
Steve
Turner,
Jane
Lomax
BMC Genomics 2013, 14 :513 (29 July 2013)
Abstract | Full text | PDF | PubMed
14.
Gene expression changes with age in skin, adipose tissue, blood and brain
Daniel
Glass,
Ana
Viñuela,
Matthew
N
Davies,
Adaikalavan
Ramasamy,
Leopold
Parts,
David
Knowles,
Andrew
A
Brown,
Åsa
K
Hedman,
Kerrin
S
Small,
Alfonso
Buil,
Elin
Grundberg,
Alexandra
C
Nica,
PaolaDi
Meglio,
Frank
O
Nestle,
Mina
Ryten,
Richard
Durbin,
Mark
I
McCarthy,
Panagiotis
Deloukas,
Emmanouil
T
Dermitzakis,
Michael
E
Weale,
Veronique
Bataille,
Tim
D
Spector
Genome Biology 2013, 14 :R75 (26 July 2013)
Abstract | Provisional PDF
| PubMed
|
Editor’s summary
Analysis of microarray experiments in subjects of varying age shows that gene expression in four different tissues changes with time
15.
DepthTools: an R package for a robust analysis of gene expression data
Aurora
Torrente,
Sara
López-Pintado,
Juan
Romo
BMC Bioinformatics 2013, 14 :237 (25 July 2013)
Abstract | Full text | PDF | PubMed
16.
Evidence of antimicrobial resistance-conferring genetic elements among pneumococci isolated prior to 1974
Kelly
L
Wyres,
Andries
van Tonder,
Lotte
M
Lambertsen,
Regine
Hakenbeck,
Julian
Parkhill,
Stephen
D
Bentley,
Angela
B
Brueggemann
BMC Genomics 2013, 14 :500 (24 July 2013)
Abstract | Full text | PDF | PubMed
17.
The KUPNetViz: a biological network viewer for multiple -omics datasets in kidney diseases
Panagiotis
Moulos,
Julie
Klein,
Simon
Jupp,
Robert
Stevens,
Jean-Loup
Bascands,
Joost
P
Schanstra
BMC Bioinformatics 2013, 14 :235 (24 July 2013)
Abstract | Full text | PDF | PubMed
18.
Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species
Keith
R
Bradnam,
Joseph
N
Fass,
Anton
Alexandrov,
Paul
Baranay,
Michael
Bechner,
Inanç
Birol,
Sébastien
Boisvert,
Jarrod
A
Chapman,
Guillaume
Chapuis,
Rayan
Chikhi,
Hamidreza
Chitsaz,
Wen-Chi
Chou,
Jacques
Corbeil,
Cristian
Del Fabbro,
T
Docking,
Richard
Durbin,
Dent
Earl,
Scott
Emrich,
Pavel
Fedotov,
Nuno
A
Fonseca,
Ganeshkumar
Ganapathy,
Richard
A
Gibbs,
Sante
Gnerre,
Élénie
Godzaridis,
Steve
Goldstein,
Matthias
Haimel,
Giles
Hall,
David
Haussler,
Joseph
B
Hiatt,
Isaac
Y
Ho
et al.
GigaScience 2013, 2 :10 (22 July 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Assemblathon 2 is the largest systematic assessment of how the process of genome assembly is carried out, with 21 participating teams submitting 43 entries based on data from 3 different genomes
19.
Identification of a neuronal transcription factor network involved in medulloblastoma development
Maria
Łastowska,
Hani
Al-Afghani,
Haya
H
Al-Balool,
Harsh
Sheth,
Emma
Mercer,
Jonathan
M
Coxhead,
Chris
PF
Redfern,
Heiko
Peters,
Alastair
D
Burt,
Mauro
Santibanez-Koref,
Chris
M
Bacon,
Louis
Chesler,
Alistair
G
Rust,
David
J
Adams,
Daniel
Williamson,
Steven
C
Clifford,
Michael
S
Jackson
Acta Neuropathologica Communications 2013, 1 :35 (11 July 2013)
Abstract | Full text | PDF
20.
The systems biology simulation core algorithm
Roland
Keller,
Alexander
Dörr,
Akito
Tabira,
Akira
Funahashi,
Michael
J
Ziller,
Richard
Adams,
Nicolas
Rodriguez,
Nicolas
Novère,
Noriko
Hiroi,
Hannes
Planatscher,
Andreas
Zell,
Andreas
Dräger
BMC Systems Biology 2013, 7 :55 (5 July 2013)
Abstract | Full text | PDF | PubMed
21.
Transcriptome analysis of human tissues and cell lines reveals one dominant transcript per gene
Mar
Gonzàlez-Porta,
Adam
Frankish,
Johan
Rung,
Jennifer
Harrow,
Alvis
Brazma
Genome Biology 2013, 14 :R70 (1 July 2013)
Abstract | Provisional PDF
| PubMed
|
Editor’s summary
Analysis of RNA-seq data across different tissues and cell lines reveals that the majority of genes have a single dominant transcript
22.
Genomic clustering and co-regulation of transcriptional networks in the pathogenic fungus Fusarium graminearum
Katherine
Lawler,
Kim
Hammond-Kosack,
Alvis
Brazma,
Richard
MR
Coulson
BMC Systems Biology 2013, 7 :52 (27 June 2013)
Abstract | Full text | PDF | PubMed
23.
Quantifying single nucleotide variant detection sensitivity in exome sequencing
Alison
M
Meynert,
Louise
S
Bicknell,
Matthew
E
Hurles,
Andrew
P
Jackson,
Martin
S
Taylor
BMC Bioinformatics 2013, 14 :195 (18 June 2013)
Abstract | Full text | PDF | PubMed | f1000
24.
Large scale variation in DNA copy number in chicken breeds
Richard
PMA
Crooijmans,
Mark
S
Fife,
Tomas
W
Fitzgerald,
Shurnevia
Strickland,
Hans
H
Cheng,
Pete
Kaiser,
Richard
Redon,
Martien
AM
Groenen
BMC Genomics 2013, 14 :398 (13 June 2013)
Abstract | Full text | PDF | PubMed
25.
bioWeb3D: an online webGL 3D data visualisation tool
Jean-Baptiste
Pettit,
John
C
Marioni
BMC Bioinformatics 2013, 14 :185 (7 June 2013)
Abstract | Full text | PDF | PubMed