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1.

Software   Open Access

MethylPCA: a toolkit to control for confounders in methylome-wide association studies

Wenan Chen, Guimin Gao, Srilaxmi Nerella, Christina M Hultman, Patrik KE Magnusson, Patrick F Sullivan, Karolina A Aberg, Edwin JCG van den Oord BMC Bioinformatics 2013, 14:74 (2 March 2013)

Abstract | Provisional PDF

2.

Methodology article   Open Access Highly Accessed

Estimation of CpG coverage in whole methylome next-generation sequencing studies

Edwin J van den Oord, Jozsef Bukszar, Gábor Rudolf, Srilaxmi Nerella, Joseph L McClay, Lin Y Xie, Karolina A Aberg BMC Bioinformatics 2013, 14:50 (12 February 2013)

Abstract | Provisional PDF | PubMed

3.

Research   Open Access Highly Accessed

Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury

Kianoush Kashani, Ali Al-Khafaji, Thomas Ardiles, Antonio Artigas, Sean M Bagshaw, Max Bell, Azra Bihorac, Robert Birkhahn, Cynthia M Cely, Lakhmir S Chawla, Danielle L Davison, Thorsten Feldkamp, Lui G Forni, Michelle Gong, Kyle J Gunnerson, Michael Haase, James Hackett, Patrick M Honore, Eric AJ Hoste, Olivier Joannes-Boyau, Michael Joannidis, Patrick Kim, Jay L Koyner, Daniel T Laskowitz, Matthew E Lissauer, Gernot Marx, Peter A McCullough, Scott Mullaney, Marlies Ostermann, Thomas Rimmelé, Nathan I Shapiro, Andrew D Shaw, Jing Shi, Amy M Sprague, Jean-Louis Vincent, Christophe Vinsonneau et al. Critical Care 2013, 17:R25 (6 February 2013)

Abstract | Provisional PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Urine TIMP-2, and IGFBP7, two novel biomarkers for risk stratification of acute kidney injury, have been discovered and validated in more than 1000 critically ill patients. 

4.

Review   Open Access

Hormonal modulation of connective tissue homeostasis and sex differences in risk for osteoarthritis of the knee

Barbara D Boyan, David A Hart, Roger M Enoka, Daniel P Nicolella, Eileen Resnick, Karen J Berkley, Kathleen A Sluka, C Kent Kwoh, Laura L Tosi, Mary I O’Connor, Richard D Coutts, Wendy M Kohrt Biology of Sex Differences 2013, 4:3 (4 February 2013)

Abstract | Full text | PDF | PubMed

5.

Poster presentation   Open Access

Quantification of thoracic aorta blood flow by magnetic resonance imaging during supine cycling exercise of increasing intensity

Laura Ellwein, John F LaDisa, Stacy Leibham, Sheila Schindler-Ivens, Margaret M Samyn Journal of Cardiovascular Magnetic Resonance 2013, 15(Suppl 1):P239 (30 January 2013)

Full text | PDF

6.

Poster presentation   Open Access

Comparison of methods for DE-CMR infarct size quantification - reproducibility among three core labs

Igor Klem, Einar Heiberg, John D Grizzard, Lowie M Van Assche, Michele Parker, Hakan Arheden, Raymond J Kim Journal of Cardiovascular Magnetic Resonance 2013, 15(Suppl 1):P180 (30 January 2013)

Full text | PDF

7.

Research article   Open Access

Mitochondrial quality, dynamics and functional capacity in Parkinson’s disease cybrid cell lines selected for Lewy body expression

Emily N Cronin-Furman, M Kathleen Borland, Kristen E Bergquist, James P Bennett, Patricia A Trimmer Molecular Neurodegeneration 2013, 8:6 (26 January 2013)

Abstract | Full text | PDF | PubMed

8.

Review   Open Access Highly Accessed

2013 WSES guidelines for management of intra-abdominal infections

Massimo Sartelli, Pierluigi Viale, Fausto Catena, Luca Ansaloni, Ernest Moore, Mark Malangoni, Frederick A Moore, George Velmahos, Raul Coimbra, Rao Ivatury, Andrew Peitzman, Kaoru Koike, Ari Leppaniemi, Walter Biffl, Clay Cothren Burlew, Zsolt J Balogh, Ken Boffard, Cino Bendinelli, Sanjay Gupta, Yoram Kluger, Ferdinando Agresta, Salomone Di Saverio, Imtiaz Wani, Alex Escalona, Carlos Ordonez, Gustavo P Fraga, Gerson Alves Pereira Junior, Miklosh Bala, Yunfeng Cui, Sanjay Marwah et al. World Journal of Emergency Surgery 2013, 8:3 (8 January 2013)

Abstract | Full text | PDF | PubMed

9.

Research article   Open Access

Long term persistence of clonal malaria parasite Plasmodium falciparum lineages in the Colombian Pacific region

Diego F Echeverry, Shalini Nair, Lyda Osorio, Sanjay Menon, Claribel Murillo, Tim JC Anderson BMC Genetics 2013, 14:2 (7 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Analysis of Plasmodium falciparum parasites from malaria patients in Colombia reveals strong subdivision and long-term persistence of clonal populations, highlighting that these aspects of population structure should be taken into account when designing drug resistance studies.

10.

Research   Open Access

Changes in subcellular localization reveal interactions between human cytomegalovirus terminase subunits

Jian Ben Wang, Yali Zhu, Michael A McVoy, Deborah S Parris Virology Journal 2012, 9:315 (21 December 2012)

Abstract | Full text | PDF | PubMed

11.

Research article   Open Access

An automated method for analysis of microcirculation videos for accurate assessment of tissue perfusion

Sumeyra U Demir, Roya Hakimzadeh, Rosalyn Hobson Hargraves, Kevin R Ward, Eric V Myer, Kayvan Najarian BMC Medical Imaging 2012, 12:37 (21 December 2012)

Abstract | Full text | PDF | PubMed

12.

Research article   Open Access

Factors associated with patient visits to the emergency department for asthma therapy

Hamdan AL-Jahdali, Ahmed Anwar, Abdullah AL-Harbi, Salim Baharoon, Rabih Halwani, Abdulllah Al Shimemeri, Saleh Al-Muhsen BMC Pulmonary Medicine 2012, 12:80 (17 December 2012)

Abstract | Full text | PDF | PubMed

13.

Research   Open Access

Species-level classification of the vaginal microbiome

Jennifer M Fettweis, Myrna G Serrano, Nihar U Sheth, Carly M Mayer, Abigail L Glascock, J Paul Brooks, Kimberly K Jefferson, Gregory A Buck BMC Genomics 2012, 13(Suppl 8):S17 (17 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

14.

Research   Open Access

Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study

Zhongming Zhao, An-Yuan Guo, Edwin JCG van den Oord, Fazil Aliev, Peilin Jia, Howard J Edenberg, Brien P Riley, Danielle M Dick, Jill C Bettinger, Andrew G Davies, Michael S Grotewiel, Marc A Schuckit, Arpana Agrawal, John Kramer, John I Nurnberger, Kenneth S Kendler, Bradley T Webb, Michael F Miles BMC Genomics 2012, 13(Suppl 8):S16 (17 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

15.

Research   Open Access

Genomic sequence analysis and characterization of Sneathia amnii sp. nov

Michael D Harwich, Myrna G Serrano, Jennifer M Fettweis, João MP Alves, Mark A Reimers, Gregory A Buck, Kimberly K Jefferson BMC Genomics 2012, 13(Suppl 8):S4 (17 December 2012)

Abstract | Full text | PDF | PubMed

16.

Research   Open Access

RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia

Junzhe Xu, Jingchun Sun, Jingchun Chen, Lily Wang, Anna Li, Matthew Helm, Steven L Dubovsky, Silviu-Alin Bacanu, Zhongming Zhao, Xiangning Chen BMC Genomics 2012, 13(Suppl 8):S2 (17 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

17.

Research article   Open Access Highly Accessed

Innovation in patient-centered care: lessons from a qualitative study of innovative health care organizations in Washington State

Peter Reed, Douglas A Conrad, Susan E Hernandez, Carolyn Watts, Miriam Marcus-Smith BMC Family Practice 2012, 13:120 (14 December 2012)

Abstract | Full text | PDF | PubMed

18.

Research   Open Access

Comparison of walking overground and in a Computer Assisted Rehabilitation Environment (CAREN) in individuals with and without transtibial amputation

Deanna H Gates, Benjamin J Darter, Jonathan B Dingwell, Jason M Wilken Journal of NeuroEngineering and Rehabilitation 2012, 9:81 (14 November 2012)

Abstract | Full text | PDF | PubMed

19.

Research   Open Access Highly Accessed

Rod microglia: elongation, alignment, and coupling to form trains across the somatosensory cortex after experimental diffuse brain injury

Jenna M Ziebell, Samuel E Taylor, Tuoxin Cao, Jordan L Harrison, Jonathan Lifshitz Journal of Neuroinflammation 2012, 9:247 (30 October 2012)

Abstract | Full text | PDF | PubMed

20.

Research article   Open Access

Staphylococcus aureus and Escherichia coli have disparate dependences on KsgA for growth and ribosome biogenesis

Heather C O’Farrell, Jason P Rife BMC Microbiology 2012, 12:244 (24 October 2012)

Abstract | Full text | PDF | PubMed

21.

Technical advance   Open Access

Non-linear dynamical signal characterization for prediction of defibrillation success through machine learning

Sharad Shandilya, Kevin Ward, Michael Kurz, Kayvan Najarian BMC Medical Informatics and Decision Making 2012, 12:116 (15 October 2012)

Abstract | Full text | PDF | PubMed

22.

Methodology   Open Access Highly Accessed

A confirmatory factor analysis of the metabolic syndrome in adolescents: an examination of sex and racial/ethnic differences

Matthew J Gurka, Christa L Ice, Shumei S Sun, Mark D DeBoer Cardiovascular Diabetology 2012, 11:128 (13 October 2012)

Abstract | Full text | PDF | PubMed

23.

Research article   Open Access Highly Accessed

A program for sustained improvement in preventing ventilator associated pneumonia in an intensive care setting

Raquel A Caserta, Alexandre R Marra, Marcelino S Durão, Cláudia Silva, Oscar Pavao dos Santos, Henrique Sutton Neves, Michael B Edmond, Karina Timenetsky BMC Infectious Diseases 2012, 12:234 (29 September 2012)

Abstract | Full text | PDF | PubMed

24.

Research   Open Access

Patient- and population-level health consequences of discontinuing antiretroviral therapy in settings with inadequate HIV treatment availability

April D Kimmel, Stephen C Resch, Xavier Anglaret, Norman Daniels, Sue J Goldie, Christine Danel, Angela Y Wong, Kenneth A Freedberg, Milton C Weinstein Cost Effectiveness and Resource Allocation 2012, 10:12 (19 September 2012)

Abstract | Full text | PDF | PubMed

25.

Research   Open Access

Behavioral and physiological female responses to male sex ratio bias in a pond-breeding amphibian

Kristine L Grayson, Stephen P De Lisle, Jerrah E Jackson, Samuel J Black, Erica J Crespi Frontiers in Zoology 2012, 9:24 (18 September 2012)

Abstract | Full text | PDF | PubMed

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