1.
Proteomics: improving biomarker translation to modern medicine?
Paul
C
Guest,
Michael
G
Gottschalk,
Sabine
Bahn
Genome Medicine 2013, 5 :17 (27 February 2013)
Abstract | Full text | PDF
|
Editor’s summary
Guest, Gottschalk and Bahn highlight the challenges and prospects for translational biomarker research in an Editorial introducing the "Proteomic applications in medicine" series.
2.
Open questions: What is there left for cell biologists to do?
Sean
Munro
BMC Biology 2013, 11 :16 (27 February 2013)
Abstract | Full text | PDF
|
Editor’s summary
In a contribution to the 10th anniversary series on open questions in biology, Sean Munro asks provocatively what there is left for cell biologists to do, and with great elan and a touch of waspish humor produces five unanswered questions on issues from the special properties of non-dividing cells to the architecture of the brain.
3.
Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts
Badri
Vardarajan,
David
Vergote,
Fadel
Tissir,
Mark
Logue,
Jing
Yang,
Nathalie
Daude,
Kunie
Ando,
Ekaterina
Rogaeva,
Joseph
Lee,
Rong
Cheng,
Jean-Pierre
Brion,
Mahdi
Ghani,
Beipei
Shi,
Clinton
T
Baldwin,
Satyabrata
Kar,
Richard
Mayeux,
Paul
Fraser,
André
M
Goffinet,
Peter
St
George-Hyslop,
Lindsay
A
Farrer,
David
Westaway
Molecular Neurodegeneration 2013, 8 :10 (15 February 2013)
Abstract | Provisional PDF
| PubMed
4.
Systems chemistry: using thermodynamically controlled networks to assess molecular similarity
Vittorio
Saggiomo,
Yana
R
Hristova,
R
Frederick
Ludlow,
Sijbren
Otto
Journal of Systems Chemistry 2013, 4 :2 (12 February 2013)
Abstract | Provisional PDF
|
Editor’s summary
|
Graphical abstract
A dynamic molecular network has been developed that represents the first experimental approach towards predicting bioactivity based on an assessment of molecular similarity
5.
B-cell depletion in SLE: clinical and trial experience with rituximab and ocrelizumab and implications for study design
Venkat
Reddy,
David
Jayne,
David
Close,
David
Isenberg
Arthritis Research & Therapy 2013, 15 (Suppl 1):S2 (11 February 2013)
Abstract | Full text | PDF
6.
The 3rd DBCLS BioHackathon: improving life science data integration with semantic Web technologies
Toshiaki
Katayama,
Mark
D
Wilkinson,
Gos
Micklem,
Shuichi
Kawashima,
Atsuko
Yamaguchi,
Mitsuteru
Nakao,
Yasunori
Yamamoto,
Shinobu
Okamoto,
Kenta
Oouchida,
Hong-Woo
Chun,
Jan
Aerts,
Hammad
Afzal,
Erick
Antezana,
Kazuharu
Arakawa,
Bruno
Aranda,
Francois
Belleau,
Jerven
Bolleman,
Raoul
Jean
Bonnal,
Brad
Chapman,
Peter
Cock,
Tore
Eriksson,
Paul
Gordon,
Naohisa
Goto,
Kazuhiro
Hayashi,
Heiko
Horn,
Ryosuke
Ishiwata,
Eli
Kaminuma,
Arek
Kasprzyk,
Hideya
Kawaji,
Nobuhiro
Kido
et al.
Journal of Biomedical Semantics 2013, 4 :6 (11 February 2013)
Abstract | Provisional PDF
| PubMed
7.
Iron status is inversely associated with dietary iron intakes in patients with inactive or mildly active inflammatory bowel disease
Jonathan
J
Powell,
William
B
Cook,
Mark
Chatfield,
Carol
Hutchinson,
Dora
IA
Pereira,
Miranda
CE
Lomer
Nutrition & Metabolism 2013, 10 :18 (1 February 2013)
Abstract | Full text | PDF | PubMed
8.
Open questions: missing pieces from the immunological jigsaw puzzle
Gillian
M
Griffiths
BMC Biology 2013, 11 :10 (31 January 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Gillian Griffiths, in her ‘Open questions’ contribution for BMC Biology, pinpoints some critical missing links in the cell-biological specializations of immune cells
9.
Assessment of myocardial and LV blood pool post-contrast T1 evolution: comparison between healthy subjects and patients with hypertrophic cardiomyopathy
Nadjia
Kachenoura,
Laila
Besson-Hajji,
Martin
J
Graves,
Scott
Reid,
Golmehr
Ashrafpoor,
Laurent
Macron,
Arshid
Azarine,
Alban
Redheuil,
Elie
Mousseaux
Journal of Cardiovascular Magnetic Resonance 2013, 15 (Suppl 1):E44 (30 January 2013)
Full text | PDF
10.
Actigraphy assessments of circadian sleep-wake cycles in the Vegetative and Minimally Conscious States
Damian
Cruse,
Aurore
Thibaut,
Athena
Demertzi,
Julia
C
Nantes,
Marie-Aurelie
Bruno,
Olivia
Gosseries,
Audrey
Vanhaudenhuyse,
Tristan
A
Bekinschtein,
Adrian
M
Owen,
Steven
Laureys
BMC Medicine 2013, 11 :18 (24 January 2013)
Abstract | Provisional PDF
| PubMed
|
Editor’s summary
Wrist actigraphy indicates that the sleep-wake cycles of patients in Vegetative states are more impaired than those in Minimally Conscious states indicating a need for improved guidelines in assessing the circadian rhythms of these patients.
11.
Genome-wide mapping of FOXM1 binding reveals co binding with estrogen receptor alpha in breast cancer cells
Deborah
A
Sanders,
Caryn
S
Ross-Innes,
Dario
Beraldi,
Jason
S
Carroll,
Shankar
Balasubramanian
Genome Biology 2013, 14 :R6 (24 January 2013)
Abstract | Provisional PDF
| PubMed
|
Editor’s summary
Binding sites for FOXM1 are mapped in breast cancer cell lines with and without estrogen receptor
12.
Epidemiology and interactions of Human Immunodeficiency Virus – 1 and Schistosoma mansoni in sub-Saharan Africa
Humphrey
D
Mazigo,
Fred
Nuwaha,
Shona
Wilson,
Safari
M
Kinung'hi,
Domenica
Morona,
Rebecca
Waihenya,
Jorg
Heukelbach,
David
W
Dunne
Infectious Diseases of Poverty 2013, 2 :2 (24 January 2013)
Abstract | Full text | PDF
|
Editor’s summary
The fishing communities of Africa remain at higher risk of acquiring both infections and co-infections. The available evidence indicates that immunological interactions of the two diseases in single human host are associated with severe morbidities. Image: Fishermen at Kayenze village, one of the fishing villages on the southern shore of the Lake Victoria, north-western Tanzania.
13.
Comparing the accuracy of two secondary food environment data sources in the UK across socio-economic and urban/rural divides
Thomas
Burgoine,
Flo
Harrison
International Journal of Health Geographics 2013, 12 :2 (17 January 2013)
Abstract | Full text | PDF | PubMed
14.
Vasohibin-1 is identified as a master-regulator of endothelial cell apoptosis using gene network analysis
Muna
Affara,
Debbie
Sanders,
Hiromitsu
Araki,
Yoshinori
Tamada,
Benjamin
J
Dunmore,
Sally
Humphreys,
Seiya
Imoto,
Christopher
Savoie,
Satoru
Miyano,
Satoru
Kuhara,
David
Jeffries,
Cristin
Print,
D Stephen
Charnock-Jones
BMC Genomics 2013, 14 :23 (16 January 2013)
Abstract | Full text | PDF | PubMed
15.
Dietary fortificant iron intake is negatively associated with quality of life in patients with mildly active inflammatory bowel disease
Jonathan
J
Powell,
William
B
Cook,
Carol
Hutchinson,
Zoe
Tolkien,
Mark
Chatfield,
Dora
IA
Pereira,
Miranda
CE
Lomer
Nutrition & Metabolism 2013, 10 :9 (15 January 2013)
Abstract | Full text | PDF | PubMed
16.
Regions of XY homology in the pig X chromosome and the boundary of the pseudoautosomal region
Benjamin
M
Skinner,
Kim
Lachani,
Carole
A
Sargent,
Nabeel
A
Affara
BMC Genetics 2013, 14 :3 (15 January 2013)
Abstract | Full text | PDF | PubMed
17.
Task-related functional connectivity in autism spectrum conditions: an EEG study using wavelet transform coherence
Ana
Catarino,
Alexandre
Andrade,
Owen
Churches,
Adam
P
Wagner,
Simon
Baron-Cohen,
Howard
Ring
Molecular Autism 2013, 4 :1 (12 January 2013)
Abstract | Full text | PDF | PubMed
18.
Wrapping up the bad news – HIV assembly and release
Bo
Meng,
Andrew
ML
Lever
Retrovirology 2013, 10 :5 (10 January 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
This review is a summary of our current understanding of the budding process of HIV, from genomic RNA capture through budding and on to viral maturation, but centering on the proteins of the ESCRT pathway and highlighting some recent advances in our understanding of the cellular components involved and the complex interplay between the Gag protein and the genomic RNA.
19.
Impact of plain packaging of tobacco products on smoking in adults and children: an elicitation of international experts’ estimates
Rachel
Pechey,
David
Spiegelhalter,
Theresa
M
Marteau
BMC Public Health 2013, 13 :18 (9 January 2013)
Abstract | Full text | PDF | PubMed
20.
Contribution of the PALB2 c.2323C>T [p.Q775X] Founder mutation in well-defined breast and/or ovarian cancer families and unselected ovarian cancer cases of French Canadian descent
Marc
Tischkowitz,
Nelly
Sabbaghian,
Nancy
Hamel,
Carly
Pouchet,
William
D
Foulkes,
Anne-Marie
Mes-Masson,
Diane
M
Provencher,
Patricia
N
Tonin
BMC Medical Genetics 2013, 14 :5 (9 January 2013)
Abstract | Full text | PDF | PubMed
21.
Network analysis and data mining in food science: the emergence of computational gastronomy
Sebastian
E
Ahnert
Flavour 2013, 2 :4 (9 January 2013)
Abstract | Full text | PDF
22.
Testing a peer support intervention for people with type 2 diabetes: a pilot for a randomised controlled trial
David
Simmons,
Simon
Cohn,
Christopher
Bunn,
Kym
Birch,
Sarah
Donald,
Charlotte
Paddison,
Candice
Ward,
Peter
Robins,
A Toby
Prevost,
Jonathan
Graffy
BMC Family Practice 2013, 14 :5 (8 January 2013)
Abstract | Full text | PDF | PubMed
23.
Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet
Jonathan
Cedernaes,
Johan
Alsiö,
Åke
Västermark,
Ulf
Risérus,
Helgi
B
Schiöth
Lipids in Health and Disease 2013, 12 :2 (8 January 2013)
Abstract | Full text | PDF | PubMed
24.
Identifying targets of the Sox domain protein Dichaete in the Drosophila CNS via targeted expression of dominant negative proteins
Shih Pei
Shen,
Jelena
Aleksic,
Steven
Russell
BMC Developmental Biology 2013, 13 :1 (5 January 2013)
Abstract | Full text | PDF | PubMed
25.
Structural and functional characteristics of cGMP-dependent methionine oxidation in Arabidopsis thaliana proteins
Claudius
Marondedze,
Ilona
Turek,
Brian
Parrott,
Ludivine
Thomas,
Boris
Jankovic,
Kathryn
S
Lilley,
Chris
Gehring
Cell Communication and Signaling 2013, 11 :1 (5 January 2013)
Abstract | Full text | PDF | PubMed