1.
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
Suzanne
A
Eccles,
Eric
O
Aboagye,
Simak
Ali,
Annie
S
Anderson,
Jo
Armes,
Fedor
Berditchevski,
Jeremy
P
Blaydes,
Keith
Brennan,
Nicola
J
Brown,
Helen
E
Bryant,
Nigel
J
Bundred,
Joy
M
Burchell,
Anna
M
Campbell,
Jason
S
Carroll,
Robert
B
Clarke,
Charlotte
E
Coles,
Gary
JR
Cook,
Angela
Cox,
Nicola
J
Curtin,
Lodewijk
V
Dekker,
Isabel
dos Santos Silva,
Stephen
W
Duffy,
Douglas
F
Easton,
Diana
M
Eccles,
Dylan
R
Edwards,
Joanne
Edwards,
D
Evans,
Deborah
F
Fenlon,
James
M
Flanagan,
Claire
Foster
et al.
Breast Cancer Research 2013, 15 :R92 (1 October 2013)
Abstract | Full text | PDF
|
Editor’s summary
Current knowledge 'gaps' in the understanding of breast cancer are examined, and research should focus on these to improve future clinical care.
2.
Benchmarking of protein descriptor sets in proteochemometric modeling (part 2): modeling performance of 13 amino acid descriptor sets
Gerard
JP
van Westen,
Remco
F
Swier,
Isidro
Cortes-Ciriano,
Jörg
K
Wegner,
John
P
Overington,
Adriaan
P
IJzerman,
Herman
WT
van Vlijmen,
Andreas
Bender
Journal of Cheminformatics 2013, 5 :42 (24 September 2013)
Abstract | Full text | PDF | PubMed
3.
A powerful latent variable method for detecting and characterizing gene-based gene-gene interaction on multiple quantitative traits
Fangyu
Li,
Jinghua
Zhao,
Zhongshang
Yuan,
Xiaoshuai
Zhang,
Jiadong
Ji,
Fuzhong
Xue
BMC Genetics 2013, 14 :89 (23 September 2013)
Abstract | Full text | PDF | PubMed
4.
Benchmarking of protein descriptor sets in proteochemometric modeling (part 1): comparative study of 13 amino acid descriptor sets
Gerard
JP
van Westen,
Remco
F
Swier,
Jörg
K
Wegner,
Adriaan
P
IJzerman,
Herman
WT
van Vlijmen,
Andreas
Bender
Journal of Cheminformatics 2013, 5 :41 (23 September 2013)
Abstract | Full text | PDF | PubMed
5.
A general linear model-based approach for inferring selection to climate
Srilakshmi
M
Raj,
Luca
Pagani,
Irene
Gallego Romero,
Toomas
Kivisild,
William
Amos
BMC Genetics 2013, 14 :87 (22 September 2013)
Abstract | Provisional PDF
| PubMed
|
Editor’s summary
A new method to identify regions of the human genome under selection combines population-specific and genome-wide patterns of background variation with environmental data to provide an improved picture of climate-related selection in human populations.
6.
Issues in the incorporation of economic perspectives and evidence into Cochrane reviews
Ian
Shemilt,
David
McDaid,
Kevin
Marsh,
Catherine
Henderson,
Evelina
Bertranou,
Jacqueline
Mallander,
Mike
Drummond,
Miranda
Mugford,
Luke
Vale,
Systematic Reviews 2013, 2 :83 (20 September 2013)
Abstract | Full text | PDF | PubMed
7.
A novel method to examine individual RNA structures within a mixed population reveals insights into the HIV-1 RNA dimerization process
Julia
Kenyon,
Liam
Prestwood,
Stuart
Le Grice,
Andrew
Lever
Retrovirology 2013, 10 (Suppl 1):P41 (19 September 2013)
Full text | PDF
8.
Mapping antigenic variation in HIV-1 envelope
Simon
Frost
Retrovirology 2013, 10 (Suppl 1):P32 (19 September 2013)
Full text | PDF
9.
Vitamin D supplementation in older people (VDOP): Study protocol for a randomised controlled intervention trial with monthly oral dosing with 12,000 IU, 24,000 IU or 48,000 IU of vitamin D3
Inez
Schoenmakers,
Roger
M
Francis,
Elaine
McColl,
Thomas
Chadwick,
Gail
R
Goldberg,
Christine
Harle,
Alison
Yarnall,
Jennifer
Wilkinson,
Jennie
Parker,
Ann
Prentice,
Terence
Aspray
Trials 2013, 14 :299 (17 September 2013)
Abstract | Full text | PDF | PubMed
10.
Preventing academic difficulties in preterm children: a randomised controlled trial of an adaptive working memory training intervention – IMPRINT study
Leona
Pascoe,
Gehan
Roberts,
Lex
W
Doyle,
Katherine
J
Lee,
Deanne
K
Thompson,
Marc
L
Seal,
Elisha
K
Josev,
Chiara
Nosarti,
Susan
Gathercole,
Peter
J
Anderson
BMC Pediatrics 2013, 13 :144 (16 September 2013)
Abstract | Full text | PDF | PubMed
11.
Muslim communities learning about second-hand smoke (MCLASS): study protocol for a pilot cluster randomised controlled trial
Hannah
Ainsworth,
Sarwat
Shah,
Faraz
Ahmed,
Amanda
Amos,
Ian
Cameron,
Caroline
Fairhurst,
Rebecca
King,
Ghazala
Mir,
Steve
Parrott,
Aziz
Sheikh,
David
Torgerson,
Heather
Thomson,
Kamran
Siddiqi
Trials 2013, 14 :295 (13 September 2013)
Abstract | Full text | PDF | PubMed
12.
Derivation and assessment of risk prediction models using case-cohort data
Jean
Sanderson,
Simon
G
Thompson,
Ian
R
White,
Thor
Aspelund,
Lisa
Pennells
BMC Medical Research Methodology 2013, 13 :113 (13 September 2013)
Abstract | Full text | PDF | PubMed
13.
The mouse pathology ontology, MPATH; structure and applications
Paul
N
Schofield,
John
P
Sundberg,
Beth
A
Sundberg,
Colin
McKerlie,
Georgios
V
Gkoutos
Journal of Biomedical Semantics 2013, 4 :18 (13 September 2013)
Abstract | Provisional PDF
| PubMed
14.
Methylation profiling and evaluation of demethylating therapy in renal cell carcinoma
Christopher
J
Ricketts,
Mark
R
Morris,
Dean
Gentle,
Salwati
Shuib,
Michael
Brown,
Noel
Clarke,
Wenbin
Wei,
Paul
Nathan,
Farida
Latif,
Eamonn
R
Maher
Clinical Epigenetics 2013, 5 :16 (13 September 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
Preclinical evidence that hypomethylating agent azacitidine reduces cancer cell growth in renal cell carcinoma.
15.
In situ studies of protein aggregation kinetics with multiparametric and superresolution imaging
Gabriele
Kaminski Schierle,
Claire
Michel,
Eric
Rees,
Dorothea
Pinotsi,
Clemens
Kaminski
Molecular Neurodegeneration 2013, 8 (Suppl 1):O15 (13 September 2013)
Full text | PDF
16.
An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse
Lucia
Daxinger,
Sarah
K
Harten,
Harald
Oey,
Trevor
Epp,
Luke
Isbel,
Edward
Huang,
Nadia
Whitelaw,
Anwyn
Apedaile,
Anabel
Sorolla,
Joan
Yong,
Vandhana
Bharti,
Joanne
Sutton,
Alyson
Ashe,
Zhenyi
Pang,
Nathan
Wallace,
Daniel
J
Gerhardt,
Marnie
E
Blewitt,
Jeffrey
A
Jeddeloh,
Emma
Whitelaw
Genome Biology 2013, 14 :R96 (11 September 2013)
Abstract | Full text | PDF | PubMed
|
Editor’s summary
A full characterization of the Momme screen for mouse genes regulating epigenetic processes includes three novel epigenetic regulators
17.
Test-retest reliability of the ‘Reading the Mind in the Eyes’ test: a one-year follow-up study
Enrique
G
Fernández-Abascal,
Rosario
Cabello,
Pablo
Fernández-Berrocal,
Simon
Baron-Cohen
Molecular Autism 2013, 4 :33 (11 September 2013)
Abstract | Full text | PDF | PubMed
18.
The physical capability of community-based men and women from a British cohort: the European Prospective Investigation into Cancer (EPIC)-Norfolk study
Victoria
L
Keevil,
Shabina
Hayat,
Nichola
Dalzell,
Stephanie
Moore,
Amit
Bhaniani,
Robert
Luben,
Nicholas
J
Wareham,
Kay-Tee
Khaw
BMC Geriatrics 2013, 13 :93 (10 September 2013)
Abstract | Full text | PDF | PubMed
19.
A hydrophilic gel matrix for single-molecule super-resolution microscopy
Patrick
JM
Zessin,
Carmen
L
Krüger,
Sebastian
Malkusch,
Ulrike
Endesfelder,
Mike
Heilemann
Optical Nanoscopy 2013, 2 :4 (10 September 2013)
Abstract | Full text | PDF
20.
Staphylococcus aureus small colony variants are susceptible to light activated antimicrobial agents
Sarah
Tubby,
Michael
Wilson,
John
A
Wright,
Ping
Zhang,
Sean
P
Nair
BMC Microbiology 2013, 13 :201 (6 September 2013)
Abstract | Full text | PDF | PubMed
21.
The legal imperative for treating rare disorders
Hanna
I
Hyry,
Jonathan
CP
Roos,
Jeremy
Manuel,
Timothy
M
Cox
Orphanet Journal of Rare Diseases 2013, 8 :135 (6 September 2013)
Abstract | Full text | PDF | PubMed
22.
Balancing exploration and exploitation in transferring research into practice: a comparison of five knowledge translation entity archetypes
Eivor
Oborn,
Michael
Barrett,
Karl
Prince,
Girts
Racko
Implementation Science 2013, 8 :104 (5 September 2013)
Abstract | Full text | PDF | PubMed
23.
The process of developing evidence-based guidance in medicine and public health: a qualitative study of views from the inside
Lou
Atkins,
Jonathan
A
Smith,
Michael
P
Kelly,
Susan
Michie
Implementation Science 2013, 8 :101 (4 September 2013)
Abstract | Full text | PDF | PubMed
24.
Alcohol assessment and feedback by e-mail for university students: main findings from the AMADEUS-1 randomised controlled trial
Jim
McCambridge,
Marcus
Bendtsen,
Nadine
Karlsson,
Ian
R
White,
Per
Nilsen,
Preben
Bendtsen
Addiction Science & Clinical Practice 2013, 8 (Suppl 1):A48 (4 September 2013)
Full text | PDF
25.
Two Pfam protein families characterized by a crystal structure of protein lpg2210 from Legionella pneumophila
Penelope
Coggill,
Ruth
Y
Eberhardt,
Robert
D
Finn,
Yuanyuan
Chang,
Lukasz
Jaroszewski,
Adam
Godzik,
Debanu
Das,
Qingping
Xu,
Herbert
L
Axelrod,
L
Aravind,
Alexey
G
Murzin,
Alex
Bateman
BMC Bioinformatics 2013, 14 :265 (3 September 2013)
Abstract | Full text | PDF | PubMed